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Cervical cancer is the most common cancer killer of women in developing countries. It has a high incidence rate of 15-30 per 100,000 women. Risk factors include HPV, smoking, multiple sexual partners, long-term birth control pill use, and HIV. Precancerous changes can be detected by Pap smears and colposcopy, allowing treatment before the disease becomes invasive. Early symptoms may include abnormal bleeding, but it can also be asymptomatic. Treatment involves radical hysterectomy, radiation, and chemotherapy depending on the FIGO stage - from local tumor to distant metastasis. Screening and HPV vaccination can help prevent cervical cancer.
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HPV brochure
Genital HPV is the most common sexually transmitted virus in the United States, with over half of sexually active men and women being infected at some point in their lives. HPV can cause genital warts and, in women, cervical cancer. While most HPV infections cause no symptoms, regular pap smears are important for women to screen for cervical cancer. Vaccines can protect against some high risk HPV types.
Cervical cancer hpv
What Are the Key Statistics About Cervical Cancer?
The American Cancer Society's estimates for cervical cancer in the United States for 2017 are:
About 12,820 new cases of invasive cervical cancer will be diagnosed.
About 4,210 women will die from cervical cancer.
Cervical pre-cancers are diagnosed far more often than invasive cervical cancer.
Cervical cancer was once one of the most common causes of cancer death for American women. But over the last 40 years, the cervical cancer death rate has gone down by more than 50%. The main reason for this change was the increased use of the Pap test. This screening procedure can find changes in the cervix before cancer develops. It can also find cervical cancer early − in its most curable stage.
Cervical cancer tends to occur in midlife. Most cases are found in women younger than 50. It rarely develops in women younger than 20. Many older women do not realize that the risk of developing cervical cancer is still present as they age. More than 15% of cases of cervical cancer are found in women over 65. However these cancers rarely occur in women who have been getting regular tests to screen for cervical cancer before they were 65. See the section, " Can cervical cancer be prevented?" and Cervical Cancer Prevention and Early Detection for more information about tests used to screen for cervical cancer.
In the United States, Hispanic women are most likely to get cervical cancer, followed by African-Americans, Asians and Pacific Islanders, and whites. American Indians and Alaskan natives have the lowest risk of cervical cancer in this country.
7 Things to Know about Cervical Cancer.
Oprah Winfrey's spotlight on Henrietta Lacks, an African-American woman who died from cervical cancer, was the inspiration for the latest infographic. Sadly, the medical vigilance and triumphs that have resulted in declining diagnoses of this preventable cancer in the USA have not been replicated in developing regions, particularly in East and Middle Africa. This infographic is for self-educational purposes only and just provides some of the fast facts up to 2017. Please consult a doctor for any medical advice.
Epidemiology of Cervical cancer
it contains anatomy , risk factors , problem worldwise and india , signs and symptoms ,screening , diagnosis and prevention of cervical cancer
Cervical CANCER Prevention : Update 2017 for Indian Gynecologists Dr. Sharda ...
This document discusses cervical cancer prevention in India. Some key points:
- Cervical cancer is the second most common cancer in women in India, with over 122,000 new cases and 67,000 deaths annually. India accounts for about 23-25% of cervical cancer cases and deaths worldwide.
- Human papillomavirus (HPV) infection, especially types 16 and 18, is the primary cause of cervical cancer. HPV is also linked to other cancers. Screening and HPV vaccination are important prevention strategies.
- Screening through cervical cancer screening programs can reduce cases and mortality, but high coverage is difficult to achieve in India due to limited resources. HPV vaccination has significantly reduced cervical cancer burden in
Breast Cancer
The Pink Ribbon is an international symbol of breast cancer awareness that identifies support for women with breast cancer. Breast cancer awareness efforts aim to educate people about symptoms and treatment to encourage early detection when survival rates are higher. Breast cancer is the most commonly diagnosed cancer in women and occurs when abnormal cells form a tumor in the breast. Risk factors include lifestyle factors like weight, activity levels, and diet, while symptoms can include lumps, swelling, pain, or discharge from the nipple. Staging looks at tumor size, spread to lymph nodes, and metastasis to determine prognosis and treatment. Prevention strategies encourage healthy habits and regular screening checkups.
Cervical Cancer
Cervical Cancer is common worldwide , ranking 3rd among all malignancies for women.
Second leading cause of cancer death.
Most of these cancers stem from infection with the Human Pappiloma Virus (HPV).
01 wells cgin
This document summarizes a presentation on the pathology of glandular neoplasia of the cervix. It discusses controversies in classifying glandular dysplasia and establishes endocervical glandular dysplasia as a precursor to adenocarcinoma-in-situ. High-grade cervical glandular intraepithelial neoplasia is classified. Biomarkers like MIB1, bcl2, and p16INK4a help distinguish mimics of high-grade CGIN. Early invasive adenocarcinoma criteria are defined, and data supports conservative treatment for stage IA1 and IA2 adenocarcinomas.
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HPV brochure
Genital HPV is the most common sexually transmitted virus in the United States, with over half of sexually active men and women being infected at some point in their lives. HPV can cause genital warts and, in women, cervical cancer. While most HPV infections cause no symptoms, regular pap smears are important for women to screen for cervical cancer. Vaccines can protect against some high risk HPV types.
Cervical cancer hpv
What Are the Key Statistics About Cervical Cancer?
The American Cancer Society's estimates for cervical cancer in the United States for 2017 are:
About 12,820 new cases of invasive cervical cancer will be diagnosed.
About 4,210 women will die from cervical cancer.
Cervical pre-cancers are diagnosed far more often than invasive cervical cancer.
Cervical cancer was once one of the most common causes of cancer death for American women. But over the last 40 years, the cervical cancer death rate has gone down by more than 50%. The main reason for this change was the increased use of the Pap test. This screening procedure can find changes in the cervix before cancer develops. It can also find cervical cancer early − in its most curable stage.
Cervical cancer tends to occur in midlife. Most cases are found in women younger than 50. It rarely develops in women younger than 20. Many older women do not realize that the risk of developing cervical cancer is still present as they age. More than 15% of cases of cervical cancer are found in women over 65. However these cancers rarely occur in women who have been getting regular tests to screen for cervical cancer before they were 65. See the section, " Can cervical cancer be prevented?" and Cervical Cancer Prevention and Early Detection for more information about tests used to screen for cervical cancer.
In the United States, Hispanic women are most likely to get cervical cancer, followed by African-Americans, Asians and Pacific Islanders, and whites. American Indians and Alaskan natives have the lowest risk of cervical cancer in this country.
7 Things to Know about Cervical Cancer.
Oprah Winfrey's spotlight on Henrietta Lacks, an African-American woman who died from cervical cancer, was the inspiration for the latest infographic. Sadly, the medical vigilance and triumphs that have resulted in declining diagnoses of this preventable cancer in the USA have not been replicated in developing regions, particularly in East and Middle Africa. This infographic is for self-educational purposes only and just provides some of the fast facts up to 2017. Please consult a doctor for any medical advice.
Epidemiology of Cervical cancer
it contains anatomy , risk factors , problem worldwise and india , signs and symptoms ,screening , diagnosis and prevention of cervical cancer
Cervical CANCER Prevention : Update 2017 for Indian Gynecologists Dr. Sharda ...
This document discusses cervical cancer prevention in India. Some key points:
- Cervical cancer is the second most common cancer in women in India, with over 122,000 new cases and 67,000 deaths annually. India accounts for about 23-25% of cervical cancer cases and deaths worldwide.
- Human papillomavirus (HPV) infection, especially types 16 and 18, is the primary cause of cervical cancer. HPV is also linked to other cancers. Screening and HPV vaccination are important prevention strategies.
- Screening through cervical cancer screening programs can reduce cases and mortality, but high coverage is difficult to achieve in India due to limited resources. HPV vaccination has significantly reduced cervical cancer burden in
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Cervical Cancer is common worldwide , ranking 3rd among all malignancies for women.
Second leading cause of cancer death.
Most of these cancers stem from infection with the Human Pappiloma Virus (HPV).
01 wells cgin
This document summarizes a presentation on the pathology of glandular neoplasia of the cervix. It discusses controversies in classifying glandular dysplasia and establishes endocervical glandular dysplasia as a precursor to adenocarcinoma-in-situ. High-grade cervical glandular intraepithelial neoplasia is classified. Biomarkers like MIB1, bcl2, and p16INK4a help distinguish mimics of high-grade CGIN. Early invasive adenocarcinoma criteria are defined, and data supports conservative treatment for stage IA1 and IA2 adenocarcinomas.
Cervical cancer
Cervical cancer is caused by HPV infection in 90% of cases and develops from pre-cancerous changes in the cervix, with risks including multiple sexual partners and smoking. Screening through Pap and HPV testing is important for early detection and treatment of pre-cancerous cells before cancer develops, with guidelines recommending Pap tests every 3 years for women ages 21-29 and co-testing with Pap and HPV tests every 5 years for women ages 30-65. Vaccines can protect against HPV but screening is still needed as other factors also contribute to cervical cancer risk.
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Cervical cancer is the most common cancer affecting women in India and is caused by human papillomavirus (HPV) infection. Risk factors include having multiple sexual partners, young age of first sexual activity, and weakened immunity. Symptoms may include abnormal bleeding or discharge, but often do not appear until later stages. Diagnosis involves tests like Pap smear, biopsy, and colposcopy. Early detection through regular Pap tests can find precancerous cells before they develop into cancer. Treatment options depend on the stage, and may include LEEP, cryosurgery, hysterectomy, or simply removing the affected area. An HPV vaccine provides protection if received before first sexual activity.
Cervical cancer
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The document summarizes information about the human papillomavirus (HPV). It notes that HPV is the most common sexually transmitted infection in the US, with over 6 million new cases annually. HPV can cause genital warts and cancers, especially cervical cancer. It discusses HPV types, risk factors, progression of cervical disease, and the HPV vaccine Gardasil. Gardasil was found to be highly effective against HPV types 16 and 18 in clinical trials, providing nearly 100% efficacy against precancerous cervical lesions caused by these high-risk HPV types.
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Cervical cancer is a major health problem, especially in developing countries like India. It is caused by certain strains of the human papillomavirus (HPV). Regular Pap screening can detect precancerous cell changes early when treatment is most effective. The HPV vaccine, when administered before sexual debut, can prevent HPV infection and thus most cervical cancers. Together, vaccination and screening can end cervical cancer as a major public health problem.
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Cervical cancer is caused by persistent HPV infection and develops from normal cervical cells turning precancerous and then cancerous, mainly in the area where the cervix meets the womb. It is the fourth most common cancer in women worldwide with over 500,000 new cases in 2012. The majority of cases and deaths occur in less developed regions, with sub-Saharan Africa having the highest rates. Risk factors include HPV infection, low screening, smoking, HIV/AIDS, young age of first sexual activity, and many sexual partners. Prevention includes vaccination against HPV, screening programs for early detection and treatment of precancerous lesions, and lifestyle behaviors to reduce risk of HPV exposure and persistence.
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The document discusses cervical cancer, including its causes, risk factors, symptoms, staging, treatment options, and prognosis factors. Some key points include:
- Cervical cancer is the 2nd most common cancer in women worldwide and the leading cause of cancer deaths in women in developing countries.
- Risk factors include HPV infection, multiple sexual partners, smoking, and other STDs. Early stages often show no symptoms while later stages can cause bleeding, discharge and pain.
- Treatment depends on cancer stage but may involve surgery, radiation therapy, chemotherapy or a combination. Prognosis depends on lymph node status, tumor size and depth of invasion among other factors.
Cervical Explained In Detail
Dr. Pk Das Is one of the famous and highly qualified doctor of cancer. He is a cervical cancer specialist in Delhi NCR. Consult Dr.PK Das for all cervical cancer related queries.
Cervical ppt
CERVICAL CANCER
By
Josfeena Bashir
Lecturer,BGSBU
outline
Definition
Causes
Types
Stages
Pathophysiology
Clinical manifestations
Diagnostic investigations
Management
Complication
DEFINITION
Cervical cancer is a disease that develops quite slowly and begins with a precancerous lesion known as dysplasia .It is a malignant tumor deriving from the cells of the cervix.
incidence
Types of cervical cancer
STAGING
PATHOPHYSIOLOGY
Due to various causes
Human papilloma virus enter into cervix
HPV Exposure(million /yr)
CONDYLOMA CERVICAL
DYSPLASIA
High grade cervical dysplasia
Invasive cancer
Metastasis
Clinical manifestations
Leg pain
Edema of the extremities.
Anaemic
Hematuria
Rectal pain
Diarrhoea
Blood per rectum
Uremia in late stage
Foul smelling urine
DIAGNOSTIC INVESTIGATIONS
Medical management
Medical management
CHEMOTHERAPY
Drug: Cisplatin
RADIATION THERAPY
External beam radiation therapy
HVD BBKHT7T6TGSERTYUIJKNBCFXHG
Surgical management
Laser surgery
LEEP
Hysterectomy
Bilateral pelvic adenectomy
Pelvic exenteration
Radical trachelectomy.
complications
Early menopause
Narrowing of the vagina
Bleeding
Lymphedema
conclusion
Epidemiology and carcinogenesis of premalignant lesions of cervix
This document discusses the epidemiology and carcinogenesis of premalignant lesions of the cervix. It notes that cervical cancer is caused by HPV in almost 100% of cases. HPV infection goes through stages of acquisition, persistence of the virus, progression to precancerous lesions like CIN 1, 2, and 3, and potential invasion if not treated. Risk factors for acquisition and persistence include early sexual activity, multiple partners, and co-factors like smoking.
Etiopathogenesis and natural history of ca cervix
CERVICAL CANCER , the 2nd most common cancer in India can be easily prevented with proper adequate screening and awareness.
Adequate sex education is necessary to inculcate safe sexual practices to prevent HPV infection.
Presentation for public awareness
Cervical cancer is caused by human papillomavirus (HPV) infection and develops slowly over time. Screening through regular Pap tests can detect precancerous changes in the cervix so they can be treated before cancer develops. Most cervical cancers are preventable with vaccination against HPV and appropriate screening. Screening guidelines recommend annual Pap tests beginning at age 21 and can be less frequent or stop at age 70 if previous results have been normal. Abnormal results may require further tests like colposcopy and HPV testing and possible treatment of precancerous lesions.
cervical cancer
Cervical cancer is the second most common cancer in women globally. It is caused by persistent infection with human papillomavirus (HPV), with types 16 and 18 causing over 70% of cases. Screening through cervical smears has significantly reduced cervical cancer rates in developed nations. Treatment depends on the stage of cancer, ranging from conization for early stage IA1 to chemoradiation for later stages. Prognosis is best for early stage disease, with 5-year survival rates over 90% for stage IA tumors.
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The document discusses human papillomavirus (HPV) and related diseases like cervical cancer. It notes that HPV types 16 and 18 cause over 70% of cervical cancers worldwide. Cervical cancer rates have declined in countries with organized cervical screening programs. HPV is transmitted sexually and often clears without symptoms, but can sometimes cause cervical lesions and genital warts.
Cervical Cancer Prevention UPDATE ON H.P.V. vaccination
Cervical cancer is a major public health problem in India. It is caused by persistent human papillomavirus (HPV) infection, with HPV types 16 and 18 causing 70% of cases. Screening through the Pap test can detect pre-cancerous lesions early, but coverage in India is very low at 2.6% due to barriers like lack of awareness, access issues, and social stigma. Prevention strategies include education, screening, and HPV vaccination to reduce cervical cancer incidence and mortality.
Pre and post interview
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The decision to delivery interval in emergency and non
This study assessed the decision to delivery interval (DDI) for emergency and non-urgent cesarean sections at King Abdulaziz University Hospital in Saudi Arabia. The study analyzed 213 cesarean sections from January to June 2008. The median DDI was 62.5 minutes for non-urgent sections and 41 minutes for emergency sections, below the recommended 30 minutes. For emergency sections, 30.6% had a DDI under 30 minutes. No correlation was found between DDI and infant Apgar scores. The study concludes that achieving the 30 minute standard for emergency sections remains important to reduce maternal anxiety, though may not impact infant outcomes.
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Cervical cancer
Cervical cancer is caused by HPV infection in 90% of cases and develops from pre-cancerous changes in the cervix, with risks including multiple sexual partners and smoking. Screening through Pap and HPV testing is important for early detection and treatment of pre-cancerous cells before cancer develops, with guidelines recommending Pap tests every 3 years for women ages 21-29 and co-testing with Pap and HPV tests every 5 years for women ages 30-65. Vaccines can protect against HPV but screening is still needed as other factors also contribute to cervical cancer risk.
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Cancer remains a leading cause of death worldwide. In Bangladesh, there are an estimated 13 to 15 lakh cancer patients, with around two lakh newly diagnosed each year. Cancers are commonly caused by smoking and diet, as well as carcinogenic chemicals in smoke, food, and the environment. Common cancer types include bladder, lung, breast, cervical, colorectal, esophageal, kidney, leukemia, liver, melanoma, non-Hodgkin lymphoma, ovarian, pancreatic, prostate, skin, stomach, thyroid, and uterine cancer. Symptoms can include fever, fatigue, pain, and skin changes. Traditional cancer treatments include surgery, radiotherapy, and chemotherapy. Lifestyle changes like not smoking, a healthy
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This document provides information from Myriad Genetics' September daily awareness calendar for ovarian cancer. Key facts include: 1) 1 in 72 women will develop ovarian cancer in their lifetime; 2) BRCA mutations account for 1 in 7 ovarian cancer cases; 3) the drug Lynparza is the first FDA-approved PARP inhibitor for ovarian cancer patients with BRCA mutations who have received 3 or more lines of chemotherapy. It encourages learning about hereditary risk factors and genetic testing options to empower women in the fight against ovarian and other gynecological cancers.
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Cervical cancer
My Topic is Cervical cancer this is the cancer which is only happened to ladies and this cancer don't have any symptoms.
Hpv Educational Presentation
The document summarizes information about the human papillomavirus (HPV). It notes that HPV is the most common sexually transmitted infection in the US, with over 6 million new cases annually. HPV can cause genital warts and cancers, especially cervical cancer. It discusses HPV types, risk factors, progression of cervical disease, and the HPV vaccine Gardasil. Gardasil was found to be highly effective against HPV types 16 and 18 in clinical trials, providing nearly 100% efficacy against precancerous cervical lesions caused by these high-risk HPV types.
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Cervical cancer is a major health problem, especially in developing countries like India. It is caused by certain strains of the human papillomavirus (HPV). Regular Pap screening can detect precancerous cell changes early when treatment is most effective. The HPV vaccine, when administered before sexual debut, can prevent HPV infection and thus most cervical cancers. Together, vaccination and screening can end cervical cancer as a major public health problem.
Cervical cancer
Cervical cancer is caused by persistent HPV infection and develops from normal cervical cells turning precancerous and then cancerous, mainly in the area where the cervix meets the womb. It is the fourth most common cancer in women worldwide with over 500,000 new cases in 2012. The majority of cases and deaths occur in less developed regions, with sub-Saharan Africa having the highest rates. Risk factors include HPV infection, low screening, smoking, HIV/AIDS, young age of first sexual activity, and many sexual partners. Prevention includes vaccination against HPV, screening programs for early detection and treatment of precancerous lesions, and lifestyle behaviors to reduce risk of HPV exposure and persistence.
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The document discusses cervical cancer, including its causes, risk factors, symptoms, staging, treatment options, and prognosis factors. Some key points include:
- Cervical cancer is the 2nd most common cancer in women worldwide and the leading cause of cancer deaths in women in developing countries.
- Risk factors include HPV infection, multiple sexual partners, smoking, and other STDs. Early stages often show no symptoms while later stages can cause bleeding, discharge and pain.
- Treatment depends on cancer stage but may involve surgery, radiation therapy, chemotherapy or a combination. Prognosis depends on lymph node status, tumor size and depth of invasion among other factors.
Cervical Explained In Detail
Dr. Pk Das Is one of the famous and highly qualified doctor of cancer. He is a cervical cancer specialist in Delhi NCR. Consult Dr.PK Das for all cervical cancer related queries.
Cervical ppt
CERVICAL CANCER
By
Josfeena Bashir
Lecturer,BGSBU
outline
Definition
Causes
Types
Stages
Pathophysiology
Clinical manifestations
Diagnostic investigations
Management
Complication
DEFINITION
Cervical cancer is a disease that develops quite slowly and begins with a precancerous lesion known as dysplasia .It is a malignant tumor deriving from the cells of the cervix.
incidence
Types of cervical cancer
STAGING
PATHOPHYSIOLOGY
Due to various causes
Human papilloma virus enter into cervix
HPV Exposure(million /yr)
CONDYLOMA CERVICAL
DYSPLASIA
High grade cervical dysplasia
Invasive cancer
Metastasis
Clinical manifestations
Leg pain
Edema of the extremities.
Anaemic
Hematuria
Rectal pain
Diarrhoea
Blood per rectum
Uremia in late stage
Foul smelling urine
DIAGNOSTIC INVESTIGATIONS
Medical management
Medical management
CHEMOTHERAPY
Drug: Cisplatin
RADIATION THERAPY
External beam radiation therapy
HVD BBKHT7T6TGSERTYUIJKNBCFXHG
Surgical management
Laser surgery
LEEP
Hysterectomy
Bilateral pelvic adenectomy
Pelvic exenteration
Radical trachelectomy.
complications
Early menopause
Narrowing of the vagina
Bleeding
Lymphedema
conclusion
Epidemiology and carcinogenesis of premalignant lesions of cervix
This document discusses the epidemiology and carcinogenesis of premalignant lesions of the cervix. It notes that cervical cancer is caused by HPV in almost 100% of cases. HPV infection goes through stages of acquisition, persistence of the virus, progression to precancerous lesions like CIN 1, 2, and 3, and potential invasion if not treated. Risk factors for acquisition and persistence include early sexual activity, multiple partners, and co-factors like smoking.
Etiopathogenesis and natural history of ca cervix
CERVICAL CANCER , the 2nd most common cancer in India can be easily prevented with proper adequate screening and awareness.
Adequate sex education is necessary to inculcate safe sexual practices to prevent HPV infection.
Presentation for public awareness
Cervical cancer is caused by human papillomavirus (HPV) infection and develops slowly over time. Screening through regular Pap tests can detect precancerous changes in the cervix so they can be treated before cancer develops. Most cervical cancers are preventable with vaccination against HPV and appropriate screening. Screening guidelines recommend annual Pap tests beginning at age 21 and can be less frequent or stop at age 70 if previous results have been normal. Abnormal results may require further tests like colposcopy and HPV testing and possible treatment of precancerous lesions.
cervical cancer
Cervical cancer is the second most common cancer in women globally. It is caused by persistent infection with human papillomavirus (HPV), with types 16 and 18 causing over 70% of cases. Screening through cervical smears has significantly reduced cervical cancer rates in developed nations. Treatment depends on the stage of cancer, ranging from conization for early stage IA1 to chemoradiation for later stages. Prognosis is best for early stage disease, with 5-year survival rates over 90% for stage IA tumors.
Breast Cancer
Breast cancer is the second leading cause of death for women today. In Singapore, one in 16 women will be diagnosed with breast cancer in their lifetime, with Chinese women at higher risk. The highest number of cases occur in women aged 55-59. While the exact causes are unknown, risk factors include family history, early menstruation, and age over 40. Regular breast exams and mammograms can aid in early detection when treatment is most effective. Preventive measures include avoiding alcohol, eating fruits and vegetables, and exercising regularly.
Endometrial cancer JNMCH AMU ALIGARH
This document discusses endometrial cancer, including its risk factors, types, staging, evaluation, treatment, and prognosis. It begins with an introduction stating that endometrial cancer is the most common gynecologic malignancy in the US. It then describes the two main types (Type I and Type II), their associated risk factors and histological features. The document outlines the FIGO staging system and discusses factors that influence prognosis. It provides guidance on evaluating and surgically staging patients, including recommended procedures for different stages of disease. The principles of treatment involve hysterectomy, with additional therapies such as radiation depending on stage, grade, and other prognostic factors.
Khartoum feb 2008
The document discusses human papillomavirus (HPV) and related diseases like cervical cancer. It notes that HPV types 16 and 18 cause over 70% of cervical cancers worldwide. Cervical cancer rates have declined in countries with organized cervical screening programs. HPV is transmitted sexually and often clears without symptoms, but can sometimes cause cervical lesions and genital warts.
Cervical Cancer Prevention UPDATE ON H.P.V. vaccination
Cervical cancer is a major public health problem in India. It is caused by persistent human papillomavirus (HPV) infection, with HPV types 16 and 18 causing 70% of cases. Screening through the Pap test can detect pre-cancerous lesions early, but coverage in India is very low at 2.6% due to barriers like lack of awareness, access issues, and social stigma. Prevention strategies include education, screening, and HPV vaccination to reduce cervical cancer incidence and mortality.
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Mission SAY No to Cervical Cancer With HPV Vaccination DR. SHARDA JAIN S...
1. Cervical cancer is a major health issue in India, accounting for 23% of new cervical cancer cases and 25% of cervical cancer deaths worldwide.
2. Human papillomavirus (HPV) infection causes cervical cancer, with vaccination providing 98-100% efficacy against HPV types.
3. Screening and vaccination can help prevent cervical cancer, but coverage in India remains low due to cost and lack of national programs.
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This document summarizes a study on cervical cancer prevalence at King Abdulaziz University Hospital. The study aimed to estimate HPV prevalence in cervical cancer cases and identify the most common histological type. It found that 167 cases were identified, with squamous cell carcinoma being the most frequent at 83%. Adenocarcinoma represented 7.7% of cases. Few other studies in Saudi Arabia found HPV DNA in 31.6-89% of cervical cancer cases. The study concluded that cervical cancer frequency and histological types at KAUH were generally consistent with literature, though keratinizing and non-keratinizing types were similar prevalence locally.
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Cervical cancer develops from the transformation zone of the cervix due to persistent HPV infection. Screening allows for early detection and treatment of pre-cancer to prevent progression to invasive cancer. Risk factors include early sexual activity, multiple partners, HIV/AIDS, and lack of screening. Screening tests can find pre-cancer which, if untreated, may develop into cancer over 10-20 years. Treatment options depend on stage, from simple hysterectomy for early stages to chemotherapy and radiation for late stages.
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Breast cancer is the most common cancer in the world, with around 2.26 million new cases diagnosed each year. With around 0.7 million fatalities per year worldwide, it is one of the major causes of death among female cancer patients. It is quite common in those aged 25 to 70, with peak prevalence in women aged 50 to 69.
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This document summarizes a study that evaluated the knowledge, attitudes, and practices of female physicians in Saudi Arabia regarding cervical cancer screening and the HPV vaccine. A survey of 200 physicians found that specialists like OBGYNs had better knowledge about HPV's role in cervical cancer and screening methods like the Pap smear test. While nearly half knew about the HPV vaccine, providing information increased the number willing to recommend it to patients. The conclusion is that continued education for physicians in Saudi Arabia could benefit prevention of HPV and cervical cancer.
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This document summarizes stem cell research projects conducted by Dr. Mohammad Abbas at King Abdulaziz University. It outlines 5 research groups: 1) Isolation and characterization of bone marrow mesenchymal stem cells from osteoarthritis patients, 2) Effect of heat shock on bone marrow MSCs from OA patients, 3) Evaluation of ex-vivo cartilage regeneration using MSCs from OA patients, 4) Impact of MSCs impregnated with cartilage paste on repairing cartilage defects in rabbits, and 5) Impact of a hyaluronic acid scaffold impregnated with MSCs and cartilage paste on surgically induced arthritis in rabbits. Additional research includes studies on the effects of catecholamines and NSAIDs
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This document outlines the establishment of a stem cell research chair at King Abdulaziz University from 2009-2015. It begins with the author attending a knee surgery course in 2009 where he learned about cartilage regeneration techniques. He then proposed creating a research chair to RACI in 2010, which involved a lengthy approval process. He built up a research team of professors and clinicians from various specialties. Research projects focused on isolating and characterizing mesenchymal stem cells, cartilage regeneration, and animal studies on rabbits. The chair fulfilled regulatory requirements like submitting annual reports and had an organizational structure to oversee the research groups.
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Bone marrow mesenchymal stem cells (BM-MSCs) and cartilage fragments were evaluated for their ability to enhance cartilage formation in an ex-vivo osteochondral defect model. BM-MSCs alone, cartilage fragments alone, or a combination of BM-MSCs and cartilage fragments were seeded into osteochondral defects. The combination of BM-MSCs and cartilage fragments showed improved cartilage formation and defect filling compared to BM-MSCs or cartilage fragments alone, as seen on histological and biochemical analysis. The results suggest that a combination of BM-MSCs and cartilage fragments may provide a more effective approach for cartilage repair.
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This study investigated the effects of heat from an arthroscope on human bone marrow-derived mesenchymal stem cells (hBMMSCs). hBMMSCs were isolated from osteoarthritis patients and exposed to heat from an illuminated arthroscope for various time periods as single cell suspensions or cell pellets. Cell suspensions exposed to heat showed decreased viability over time, while cell pellets maintained or increased viability. Gene expression analysis found increased expression of heat shock and inflammatory genes in cell suspensions compared to pellets after heat exposure. The results suggest that transplanting hBMMSCs as cell pellets may better protect them from heat effects during arthroscopic procedures and thus support cartilage regeneration.
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This document provides an agenda and speaker information for a 3-day international colposcopy workshop taking place in Jeddah, Saudi Arabia from January 12-14, 2014. The workshop will focus on cervical cancer prevention, advances in understanding HPV, and management of lower genital tract diseases. It will include lectures, hands-on training, and case reviews led by experts from Europe, Canada, and Saudi Arabia. The goal is to train participants and raise awareness of cervical cancer screening and prevention methods.
The international federation for cervical pathology and colposcopy course
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The international federation for cervical pathology and colposcopy course
The document discusses how God created humans from dust, then a sperm-drop, then a clinging clot, and then a lump of flesh to show how He develops humans. It notes that God determines the term people will stay in the womb, then brings them out as children to reach maturity. It also mentions that some people die early while others live to a very old age. The document ends by describing how the earth appears barren but grows beautiful plants when watered.
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This document discusses treatment approaches for early stage cervical cancer. It notes that for invasive cervical cancers measuring less than 2 cm, removal of the parametrium may be omitted. For some very small tumors, pelvic lymphadenectomy can also be omitted as the risk of lymph node metastasis is limited. It also discusses outcomes from vaginal trachelectomy and laparoscopic pelvic lymphadenectomy for early stage cancers. The document considers conservative treatment approaches for stage IA2-IB1 cancers less than 3 cm in size, including a proposed study design stratifying patients based on tumor diameter.
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Adenocarcinoma in situ (AIS) is the only known precursor to cervical adenocarcinoma. Appropriate management of AIS can prevent invasive adenocarcinoma in many cases. Cytology has lower sensitivity for detecting AIS compared to HPV testing. The usual interval between detectable AIS and invasive adenocarcinoma is at least 5 years, allowing time for screening and intervention. Glandular neoplasms account for about 25% of annual cervical cancer diagnoses. Management of AIS typically involves conization, though hysterectomy is the standard treatment due to the high risk of residual disease with conization alone. HPV testing can help monitor women with AIS who wish to preserve fertility after
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This document summarizes key findings about HPV natural history and HPV testing for cervical cancer screening. It was found that HPV infection is very common but rarely leads to cancer. While persistent HPV infection can cause cervical cancer after 10-15 years, many cofactors are also involved in cancer development. Studies showed that HPV becomes undetectable within 2 years for most women. HPV testing was found to detect more pre-cancer than pap smears but also detected more lesions that may regress. HPV testing allows longer screening intervals for HPV-negative women and better protection against cancer compared to pap smears alone. While HPV testing is more effective, implementing new screening strategies poses challenges where pap smear systems are already in place.
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This document provides guidelines for colposcopy management from the IFCCP Jeddah Jan 2014 conference and the ASCCP Management Guidelines 2012 and SOGC SCC Colposcopy Guidelines 2012. It discusses recommendations and algorithms for evaluating and managing various abnormal cytology results and histological findings identified during colposcopy, including ASCUS, LSIL, ASC-H, HSIL, AGC, cervical intraepithelial neoplasia grades, and other conditions. Management may involve repeat testing, colposcopy, biopsy, excisional procedures, or return to routine screening depending on the abnormality, risk level, and other factors.
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Genital HPV is very common, with a lifetime risk of 70% for HPV infection and 10% for genital warts. Spontaneously, genital warts resolve in 20-30% of cases within 3 months. Biopsy is usually not required for healthy women under 35 years old with typical genital warts. Treatment choices depend on factors like patient preference, provider experience, and pregnancy status. Combination therapies may be used. Even after treatment, the latent virus remains, with a 30% recurrence rate of warts and potential for transmission to partners.
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This document discusses options for cervical cancer screening including visual inspection with acetic acid (VIA), cervical cytology, HPV testing, and combinations of tests. It reviews the strengths and limitations of different screening methods and highlights priorities for efficient, low-cost screening in low-resource settings. Optimal screening may involve initial HPV testing at age 35 with reflex cytology for positives and cytology follow-up of negatives before longer rescreening intervals.
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The international federation for cervical pathology and colposcopy course
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- 1. Cervical Cancer DR KHALID H. WALI SAIT (FRCSC) ASSOCIATE PROFESSOR OF GYNECOLOGICAL ONCOLOGY King Abdulaziz University Hospital, Jeddah, Saudi Arabia
- 2. Cancer Of Cervix Epidemiology Incidence is 15-30 /100000 2.6 % of all cancer in women The most common cancer killer for women in developing countries
- 3. Cancer in Women World Wide Breast Colo-rectal Cervix and Uterus Lung Leukemia- Lymphoma Ovary Saudi Breast Thyroid Leukemia– Lymphoma Colo-rectal Ovary Liver Cervix Uterus
- 4. Female Genital Tract Malignancy World Wide Uterus Cervix Ovary Vulva Vagina F.Tube Saudi Ovary Cervix Uterus Vulva Vagina F.Tube
- 5. Cervical Cancer Prevention Education About early symptom of cancer cervix Avoid Risk Factors Screening and Vaccine
- 6. Risk Co Factor: HIV HPV 16,18 SMOKING MULTIPPLE SEXUAL PARTNER ? BCP
- 7. Cancer Cervix Has an easily identified pre-invasive disease and be diagnosed and treated before become an invasive disease Screening Test
- 8. Metaplasia Dysplasia Neoplasia
- 9. Changes in Terminology HPV Mild Dysplasia HPV CIN I L SIL Moderate Dysplasia CIN II H SIL Severe Dysplasia Carcinoma insitu CIN III H SIL
- 10. Management Of Pap Smear Result Pap smear is simply a lab test it is the responsibility of the physician to interpret the result in the context of a given patient and her particular circumstances
- 12. Objective Of Colposcopy Exclude invasive disease Select the most appropriate area for biopsy
- 14. Cancer of the Cervix Clinical presentation Abnormal vaginal bleeding Postmenopausal Vaginal bleeding Vaginal discharge Pain Asymptomatic
- 15. Cancer of the Cervix FIGO Staging ( clinical ) I - Tumour confined to the cervix II- Upper 2/3 vagina / parametrium. III- Lower 1/3 vagina / pelvic side wall or hydronephrosis IV- Adjacent organ / Distant metastasis
- 16. Cancer of the Cervix Treatment of patients Radical Hysterectomy and lymphadnectomy Radiation Therapy and chemotherapy
- 17. Cervical Cancer DR KHALID H. WALI SAIT (FRCSC) ASSOCIATE PROFESSOR OF GYNECOLOGICAL ONCOLOGY King Abdulaziz University Hospital, Jeddah, Saudi Arabia
Editor's Notes
- 1920 colposcopy 1930 was used in Europe USA ACCSP SHORT FOCAL LENGTH CAN NOT DO BIOPSY LONG FOCAL LENGTH NOT COMFORTABLE PERFORM BIOPSY 5 % UNSATSF COLPOSCOPY
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- 1920 colposcopy 1930 was used in Europe USA ACCSP SHORT FOCAL LENGTH CAN NOT DO BIOPSY LONG FOCAL LENGTH NOT COMFORTABLE PERFORM BIOPSY 5 % UNSATSF COLPOSCOPY
- 1920 colposcopy 1930 was used in Europe USA ACCSP SHORT FOCAL LENGTH CAN NOT DO BIOPSY LONG FOCAL LENGTH NOT COMFORTABLE PERFORM BIOPSY 5 % UNSATSF COLPOSCOPY