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R VAISHNAVI
CRI
A 41 year old female
patient reported with
the chief complaint of
deposits on the teeth
for the past 2 years and
pain in the left side of
the face during intake
of citrus food and cold
food.
HISTORY OF PRESENTING ILLNESS
History of pricking pain on the left side of the face
during intake of citrus food and cold food
radiating to the left ear.
PAST MEDICAL HISTORY
History of incidence of mumps 8 times before 5
years and during the last incidence of mumps
unilateral swelling was present on the left side of
the face.
PAST DENTAL HISTORY
Undergone scaling before 2 years.
SYSTEMIC REVIEW
No relevant history.
PERSONAL HISTORY
History of tobacco (Supari) chewing for a year
before 1 year.
FAMILY HISTORY
No relevant history.
EXTRAORAL EXAMINATION
Bilateral diffuse
swelling seen in the
parotid region.
Mouth opening -
22.5mm
TMJ:
No abnormalities
detected.
MUSCLES OF MASTICATION :
INSPECTION- Bilateral diffuse swelling
seen in the right and left parotid region of
size 4x3 on right and left side, shape is
roughly oval, extending from tragus till the
angle of the mandible, skin of the swelling
appears normal.
PALPATION- Firm in consistency with no
palpable masses or any local rise in
temperature and non tender.
SALIVA-Both parotid ducts were patent and
on milking of parotid gland saliva was
readily expressed from Stensen’s duct.
SALIVARY GLAND
Parotid enlargement
INTRAORAL EXAMINATION
SOFT TISSUE EXAMINATION
On inspection,
Presence of blanched area evident on right and left buccal
mucosa.On palpation,
• Inspectory findings with relation to site, size, shape and
extent were confirmed and presence of fibrotic band
seen.
HARD TISSUE EXAMINATION
No contributory findings seen.
LOCAL EXAMINATION
AREA OF INTEREST : Right and left parotid
region
EXTRAORAL EXAMINATION :
INSPECTION : Bilateral diffuse swelling seen in the right
and left parotid region of size 4x3 on right and left side,
shape is roughly oval, extending from tragus till the angle
of the mandible, skin of the swelling appears normal.
PALPATION : It is firm in consistency with no palpable
masses or any local rise in temperature and non tender.
SALIVA : Both parotid ducts were patent and on milking of
parotid gland saliva was readily expressed from Stensen’s
duct.
INTRAORAL EXAMINATION
 HARD TISSUE
INSPECTION : No abnormalities detected.
PALPATION : No tenderness on palpation.
 SOFT TISSUE
INSPECTION : No abnormalities detected.
PALPATION : No tenderness on palpation.
INTRAORAL EXAMINATION
 HARD TISSUE
INSPECTION : No abnormalities detected.
PALPATION : No tenderness on palpation.
 SOFT TISSUE
INSPECTION : Blanched area seen in right and left buccal mucosa.
PALPATION : Presence of fibrotic bands in right and left buccal
mucosa and is non tender.
AREA OF INTEREST : Right and left buccal
mucosaEXTRAORAL EXAMINATION
INSPECTION : No abnormalities detected.
PALPATION : No tenderness on palpation.
CASE ANALYSIS :
A 44 years old female patient came to the department of oral medicine and
radiology with a chief complaint of deposits on teeth and pain in the left side of
the face during intake of citrus food and cold food. Patient has a history of
incidence of mumps 8 times before 5 years and during the last incidence of
mumps unilateral swelling was present on the left side of the face. Patient has a
history of tobacco (Supari) chewing for a year before 1 year.
No abnormalities detected on general examination and systemic review.
On extraoral examination, bilateral diffuse swelling seen in the right and left
parotid region of size 4x3 on right and left side, shape is roughly oval, extending
from tragus till the angle of the mandible, skin of the swelling appears normal. It
is firm in consistency with no palpable masses or any local rise in temperature and
non tender. Patient has a restricted mouth opening of 22.5mm.
On intraoral examination, blanched area seen on right and left buccal mucosa.
On palpation, fibrotic bands in right and left buccal mucosa and no tenderness was
present.
On considering patient’s chief complaint, history of presenting illness, intraoral
 PROVISIONAL DIAGNOSIS :
Oral submucous fibrosis.
Sialosis
 DIFFERENTIAL DIAGNOSIS :
FOR OSMF FOR PAROTID
ENLARGEMENT
Anemia
Scleroderma
Amyloidosis
Mumps
Lymphadenitis
Mikulicz’ disease
Sjogren’s syndrome
 INVESTIGATION :
USG, CBC, Blood glucose level and blood pressure
RAGIOGRAPHIC DIAGNOSIS
OPG dated 3/7/18 reveals well defined radiopaque structure in
the periapical region of 37 and 45 surrounded by radiolucent
band suggesting idiopathic osteosclerosis.
 FINAL DIAGNOSIS :
Oral submucous fibrosis
Sialosis
 PROGNOSIS : Fair
 TREATMENT PLAN :
 Patient education and motivation.
Advice bland food intake.
Intralesional dexamethasone injection 1 vial, biweekly for
6 weeks.
REVIEW OF LITERATURE
ORAL SUBMUCOUS FIBROSIS
Oral submucous fibrosis (OSF) is a chronic,
progressive, scarring disease, that
predominantly affects people of South-East
Asian origin.
HISTORY
 In 1952, Schwartz coined the term atrophica
idiopathica mucosa oris to describe an oral
fibrosing disease.
 Joshi subsequently coined the term oral
submucous fibrosis for the condition in
1953.
ETIOLOGY
LOCAL
FACTORS
CHILLI
ARECANUT
(MAJOR
ETIOLOGY)
SYSTEMIC
FACTORS
NUTRITIONAL
DEFICIENCY
GENETIC
Areca nut
Consists of
Alkaloids
Guvacoline
Guvacine
Arecaidine
Arecoline
Flavanoids
Catechins
Tannins
PATHOGENESIS
Chronic placement of betel quid
Arecoline
Arecaidine
Fibroblast stimulation and
proliferation
Increased collage synthesis
Fibrosis
Rigidity and limited mouth
opening
Role of Arecoline:
Role of tannins (Stabilization of
collagen)
Large quantity of tannins in
areca nut
Reduced collagen degradation
Inhibits
collagenase
CLINICAL FEATURES
Clinical staging
National journal of maxillofacial surgery, 201
STAGE I / Early OSMF
 Erythematous mucosa
 Vesicles
 Mucosal ulcers
 Melanotic mucosal
pigmentation and
mucosal
petechiae
STAGE II / MODERATE OSMF
 Blanching of the
oral mucosa
 Vertical and circular
palpable fibrous bands
 Marble-like
appearance
 Blanched and
leathery
floor of the mouth
 Shrunken cheeks
and
STAGE III / SEVERE OSMF
 Leukoplakia and
erythroplakia is
present
 Speech and hearing
difficulties may
occur
Functional staging
Staging/Grading Maximum intericisal mouth opening
Stage I
Stage II
Stage III
Stage IV
Stage V
Maximum interincisal mouth opening up to or
>35 mm
Maximum interincisal mouth opening between
25 and 35 mm
Maximum interincisal mouth opening between
15 and 25 mm
Maximum interincisal mouth opening between
5 and 15mm
Maximum interincisal mouth opening between
<5 or nil
National journal of maxillofacial surgery, 201
TREATMENT
MODALITIES
The reduction or even
elimination of the habit
of areca nut chewing is
an important
preventive measure.
NUTRITIONAL
SUPPORT
IMMUNOMODULATORY
DRUGS
Diet rich in iron, vitamins, and minerals should
be advised to patients with OSMF
Local and systemic applications of
glucocorticoids and placental extracts are
commonly used.
PHYSIOTHERAPY
This includes measures such as forceful mouth opening
and heat therapy. Heat has been commonly used and
the results have been described as satisfactory.
LOCAL DRUG
DELIVERY
Local injections of corticosteroids and placental
extract have been tried, in addition to hyaluronidase,
collagenase and similar substances which break down
intercellular cement substances and also decrease
collagen formation.
SURGICAL
MANAGEMENT
COMBINED THERAPY
With peripheral vasodilators (nylidrin hydrochloride),
vitamins D, E and ‘B’ complex, iodine, placental
extract, local and systemic corticosteroids and
physiotherapy claim a high success rate in OSF
management
• Surgical intervention is done which includes simple
excision of fibrotic bands with reconstruction using
buccal fat pad and split thickness graft.
•Fibrous resection has led to more fibrosis.

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Case report-bilateral parotid swelling with oral submucous fibrosis

  • 2. A 41 year old female patient reported with the chief complaint of deposits on the teeth for the past 2 years and pain in the left side of the face during intake of citrus food and cold food.
  • 3. HISTORY OF PRESENTING ILLNESS History of pricking pain on the left side of the face during intake of citrus food and cold food radiating to the left ear. PAST MEDICAL HISTORY History of incidence of mumps 8 times before 5 years and during the last incidence of mumps unilateral swelling was present on the left side of the face.
  • 4. PAST DENTAL HISTORY Undergone scaling before 2 years. SYSTEMIC REVIEW No relevant history.
  • 5. PERSONAL HISTORY History of tobacco (Supari) chewing for a year before 1 year. FAMILY HISTORY No relevant history.
  • 7. Bilateral diffuse swelling seen in the parotid region.
  • 8.
  • 9. Mouth opening - 22.5mm TMJ: No abnormalities detected. MUSCLES OF MASTICATION :
  • 10. INSPECTION- Bilateral diffuse swelling seen in the right and left parotid region of size 4x3 on right and left side, shape is roughly oval, extending from tragus till the angle of the mandible, skin of the swelling appears normal. PALPATION- Firm in consistency with no palpable masses or any local rise in temperature and non tender. SALIVA-Both parotid ducts were patent and on milking of parotid gland saliva was readily expressed from Stensen’s duct. SALIVARY GLAND Parotid enlargement
  • 12. SOFT TISSUE EXAMINATION On inspection, Presence of blanched area evident on right and left buccal mucosa.On palpation, • Inspectory findings with relation to site, size, shape and extent were confirmed and presence of fibrotic band seen.
  • 13. HARD TISSUE EXAMINATION No contributory findings seen.
  • 15. AREA OF INTEREST : Right and left parotid region EXTRAORAL EXAMINATION : INSPECTION : Bilateral diffuse swelling seen in the right and left parotid region of size 4x3 on right and left side, shape is roughly oval, extending from tragus till the angle of the mandible, skin of the swelling appears normal. PALPATION : It is firm in consistency with no palpable masses or any local rise in temperature and non tender. SALIVA : Both parotid ducts were patent and on milking of parotid gland saliva was readily expressed from Stensen’s duct.
  • 16. INTRAORAL EXAMINATION  HARD TISSUE INSPECTION : No abnormalities detected. PALPATION : No tenderness on palpation.  SOFT TISSUE INSPECTION : No abnormalities detected. PALPATION : No tenderness on palpation.
  • 17. INTRAORAL EXAMINATION  HARD TISSUE INSPECTION : No abnormalities detected. PALPATION : No tenderness on palpation.  SOFT TISSUE INSPECTION : Blanched area seen in right and left buccal mucosa. PALPATION : Presence of fibrotic bands in right and left buccal mucosa and is non tender. AREA OF INTEREST : Right and left buccal mucosaEXTRAORAL EXAMINATION INSPECTION : No abnormalities detected. PALPATION : No tenderness on palpation.
  • 18. CASE ANALYSIS : A 44 years old female patient came to the department of oral medicine and radiology with a chief complaint of deposits on teeth and pain in the left side of the face during intake of citrus food and cold food. Patient has a history of incidence of mumps 8 times before 5 years and during the last incidence of mumps unilateral swelling was present on the left side of the face. Patient has a history of tobacco (Supari) chewing for a year before 1 year. No abnormalities detected on general examination and systemic review. On extraoral examination, bilateral diffuse swelling seen in the right and left parotid region of size 4x3 on right and left side, shape is roughly oval, extending from tragus till the angle of the mandible, skin of the swelling appears normal. It is firm in consistency with no palpable masses or any local rise in temperature and non tender. Patient has a restricted mouth opening of 22.5mm. On intraoral examination, blanched area seen on right and left buccal mucosa. On palpation, fibrotic bands in right and left buccal mucosa and no tenderness was present. On considering patient’s chief complaint, history of presenting illness, intraoral
  • 19.  PROVISIONAL DIAGNOSIS : Oral submucous fibrosis. Sialosis  DIFFERENTIAL DIAGNOSIS : FOR OSMF FOR PAROTID ENLARGEMENT Anemia Scleroderma Amyloidosis Mumps Lymphadenitis Mikulicz’ disease Sjogren’s syndrome
  • 20.  INVESTIGATION : USG, CBC, Blood glucose level and blood pressure RAGIOGRAPHIC DIAGNOSIS OPG dated 3/7/18 reveals well defined radiopaque structure in the periapical region of 37 and 45 surrounded by radiolucent band suggesting idiopathic osteosclerosis.
  • 21.  FINAL DIAGNOSIS : Oral submucous fibrosis Sialosis  PROGNOSIS : Fair  TREATMENT PLAN :  Patient education and motivation. Advice bland food intake. Intralesional dexamethasone injection 1 vial, biweekly for 6 weeks.
  • 24. Oral submucous fibrosis (OSF) is a chronic, progressive, scarring disease, that predominantly affects people of South-East Asian origin.
  • 25. HISTORY  In 1952, Schwartz coined the term atrophica idiopathica mucosa oris to describe an oral fibrosing disease.  Joshi subsequently coined the term oral submucous fibrosis for the condition in 1953.
  • 29. Chronic placement of betel quid Arecoline Arecaidine Fibroblast stimulation and proliferation Increased collage synthesis Fibrosis Rigidity and limited mouth opening Role of Arecoline:
  • 30. Role of tannins (Stabilization of collagen) Large quantity of tannins in areca nut Reduced collagen degradation Inhibits collagenase
  • 32. Clinical staging National journal of maxillofacial surgery, 201
  • 33. STAGE I / Early OSMF  Erythematous mucosa  Vesicles  Mucosal ulcers  Melanotic mucosal pigmentation and mucosal petechiae
  • 34. STAGE II / MODERATE OSMF  Blanching of the oral mucosa  Vertical and circular palpable fibrous bands  Marble-like appearance  Blanched and leathery floor of the mouth  Shrunken cheeks and
  • 35. STAGE III / SEVERE OSMF  Leukoplakia and erythroplakia is present  Speech and hearing difficulties may occur
  • 36. Functional staging Staging/Grading Maximum intericisal mouth opening Stage I Stage II Stage III Stage IV Stage V Maximum interincisal mouth opening up to or >35 mm Maximum interincisal mouth opening between 25 and 35 mm Maximum interincisal mouth opening between 15 and 25 mm Maximum interincisal mouth opening between 5 and 15mm Maximum interincisal mouth opening between <5 or nil National journal of maxillofacial surgery, 201
  • 38. The reduction or even elimination of the habit of areca nut chewing is an important preventive measure.
  • 39. NUTRITIONAL SUPPORT IMMUNOMODULATORY DRUGS Diet rich in iron, vitamins, and minerals should be advised to patients with OSMF Local and systemic applications of glucocorticoids and placental extracts are commonly used.
  • 40. PHYSIOTHERAPY This includes measures such as forceful mouth opening and heat therapy. Heat has been commonly used and the results have been described as satisfactory. LOCAL DRUG DELIVERY Local injections of corticosteroids and placental extract have been tried, in addition to hyaluronidase, collagenase and similar substances which break down intercellular cement substances and also decrease collagen formation.
  • 41. SURGICAL MANAGEMENT COMBINED THERAPY With peripheral vasodilators (nylidrin hydrochloride), vitamins D, E and ‘B’ complex, iodine, placental extract, local and systemic corticosteroids and physiotherapy claim a high success rate in OSF management • Surgical intervention is done which includes simple excision of fibrotic bands with reconstruction using buccal fat pad and split thickness graft. •Fibrous resection has led to more fibrosis.

Editor's Notes

  1. Change the title. Restricted mouth opening and Bilateral parotid swelling – is there any correlation? (Some thing interesting as above)
  2. In the histories please remove ‘patient has a'
  3. Please remove ‘patient has'
  4. Please remove ‘patient has a’
  5. Bilateral ‘diffuse’ swelling
  6. Area of interest: right and left parotid region Extra oral examination: Inspection: bilateral diffuse swelling seen in the right and left parotid region of size_________, shape_______, extent___________, skin of the swelling___________ Palpation: Consistency____________, tenderness Saliva flow (unstimulated total saliva)/ min________, viscosity__________ Intra oral examination: Soft tissue examination: Inspection: Palpation: Hard tissue examination: Inspection: Palpation: With similar headings write for the second lesion (OSMF) bt in the soft tissue examination, write as it.