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BLOOD VESSEL SEGMENTATION OF FUNDUS IMAGES BY MAJOR VESSEL
EXTRACTION AND SUBIMAGE CLASSIFICATION
ABSTRACT
This paper presents a novel three-stage blood vesselsegmentation algorithm using funds
photographs. In the firststage, the green plane of a fundus image is preprocessed to extracta
binary image after high-pass filtering, and another binary imagefrom the morphologically
reconstructed enhanced image forthe vessel regions. Next, the regions common to both the
binaryimages are extracted as the major vessels. In the second stage, allremaining pixels in the
two binary images are classified using aGaussian mixture model (GMM) classifier using a set of
eight featuresthat are extracted based on pixel neighborhood and first andsecond-order gradient
images. In the third postprocessing stage,the major portions of the blood vessels are combined
with the classifiedvessel pixels. The proposed algorithm is less dependent ontraining data,
requires less segmentation time and achieves consistentvessel segmentation accuracy on normal
images as well asimages with pathology when compared to existing supervised
segmentationmethods. The proposed algorithm achieves a vessel segmentationaccuracy of
95.2%, 95.15%, and 95.3% in an average of3.1, 6.7, and 11.7 s on three public datasets DRIVE,
STARE, andCHASE_DB1, respectively.

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Blood vessel segmentation of fundus images by major vessel extraction and subimage classification

  • 1. BLOOD VESSEL SEGMENTATION OF FUNDUS IMAGES BY MAJOR VESSEL EXTRACTION AND SUBIMAGE CLASSIFICATION ABSTRACT This paper presents a novel three-stage blood vesselsegmentation algorithm using funds photographs. In the firststage, the green plane of a fundus image is preprocessed to extracta binary image after high-pass filtering, and another binary imagefrom the morphologically reconstructed enhanced image forthe vessel regions. Next, the regions common to both the binaryimages are extracted as the major vessels. In the second stage, allremaining pixels in the two binary images are classified using aGaussian mixture model (GMM) classifier using a set of eight featuresthat are extracted based on pixel neighborhood and first andsecond-order gradient images. In the third postprocessing stage,the major portions of the blood vessels are combined with the classifiedvessel pixels. The proposed algorithm is less dependent ontraining data, requires less segmentation time and achieves consistentvessel segmentation accuracy on normal images as well asimages with pathology when compared to existing supervised segmentationmethods. The proposed algorithm achieves a vessel segmentationaccuracy of 95.2%, 95.15%, and 95.3% in an average of3.1, 6.7, and 11.7 s on three public datasets DRIVE, STARE, andCHASE_DB1, respectively.