This is a PowerPoint presentation for Topic 1 in the Edexcel Biology B A Level course that starts in 2015.
This is a free sample, the full PowerPoint presentation is available to purchase here: https://sellfy.com/MrExham
1. Of the following, which is a difference between prokaryotic and e.pdfarchanadesignfashion
1. Of the following, which is a difference between prokaryotic and eukaryotic cells?
A. Eukaryotic cells have a nuclear envelope surrounding the genetic material, whereas
prokaryotes have no nucleus.
B. Prokaryotic cells have multiple paired chromosomes, but eukaryotic cells have
only one.
C. Prokaryotic cells have linear DNA, whereas eukaryotes have circular DNA.
D. Eukaryotes have histone proteins, whereas prokaryotes do not.
E. Plasmids contain some genes for eukaryotes, whereas organelles contain some
genes for prokaryotes.
2. Which of the following are fundamental events that must take place in cell reproduction?
A. A cell\'s genetic information must be copied.
B. The copies of the genetic information must be separated from one another.
C. The cell must divide.
D. All of the above are fundamental events that must take place in cell
reproduction.
3. What are three essential structural elements of a functional eukaryotic chromosome?
A. Histone proteins, spindle fibers, and a pair of telomeres
B. Origins of replication, chromatids, and kinetochores
C. A centromere, a pair of telomeres, and origins of replication
D. A centromere, chromatids, and kinetochores
E. Spindle fibers, kinetochores, and chromatids
4. The chromosomal structures that serve as the attachment point for spindle fibers are the
_____________________.
A. telomeres
B. origins of replication
C. centromeres
D. kinetochore proteins
E. histone proteins
5. The natural ends of eukaryotic chromosomes that serve to stabilize the ends of the
chromosomes are the ______________________.
A. telomeres
B. origins of replication
C. centromeres
D. kinetochore proteins
E. histone proteins
6. _______________ is the part of interphase within the cell cycle where the cell growth and
protein synthesis necessary for cell division and DNA replication take place.
A. G1
B. S
C. G2
D. M
E. Telophase
7. __________________ is the part of interphase within the cell cycle where additional
biochemical reactions take place preparing the cell for mitosis.
A. G1
B. S
C. G2
D. M
E. Telophase
8. __________________ is the part of interphase within the cell cycle where DNA replication
takes place.
A. G1
B. S
C. G2
D. M
E. Telophase
9. What are checkpoints?
A. Key transition points in the cell cycle that lead to cancer
B. Periods during the cell cycle that ensure all cellular components are in good
working order
C. Transition points during the process of replication that allow DNA repair
D. The last process that occurs before a cell divides
E. Critical points that ensure correct and complete cytokinesis
10. What is the stage in mitosis when sister chromatids separate at the centromere and move to
opposite poles of the cell.
A. Prophase
B. Prometaphase
C. Metaphase
D. Anaphase
E. Telophase
11. What is the stage of mitosis where the chromosomes are arranged on the equatorial plane of
the cell.
A. prophase
B. prometaphase
C. metaphase
D. anaphase
E. telophase
12. What is the stage of mitosis where the chromosomes ini.
All living beings are made up of cells. The structural and functional unit of life is a cell which is the building block of the body. New cell arises from the pre-existing cells by the process of cell division.
Cell division occurs in all living organisms. In unicellular organisms, cell division directly produces two individuals. In multicellular organisms or higher-level organisms, life begins from a single cell, as a zygote, whIch divides and redivides mitotically into a number of cells to form a complete organism.
In multicellular organisms, there are two types of cells.
a)The somatic cells or the body cells- They form the body of an organism.
b)The reproductive cells or sex cells- They are gamete-producing cells.
All living beings are made up of cells. The structural and functional unit of life is a cell which is the building block of the body. New cell arises from the pre-existing cells by the process of cell division.
Cell division occurs in all living organisms. In unicellular organisms, cell division directly produces two individuals. In multicellular organisms or higher-level organisms, life begins from a single cell, as a zygote, whIch divides and redivides mitotically into a number of cells to form a complete organism.
In multicellular organisms, there are two types of cells.
a)The somatic cells or the body cells- They form the body of an organism.
b)The reproductive cells or sex cells- They are gamete-producing cells.
Lab TemplateWeek 4 MeiosisSubmitted by your name here.docxDIPESH30
Lab Template
Week 4: Meiosis
Submitted by: <your name here>
As you complete the lab, record your answers in this template. Save the document as LastName_FirstName_BIO1020_W4A3, and submit it to the Dropbox. Full lab instructions and the rubric with which you will be evaluated can be found in the online classroom.
Activity
Cellular reproduction in Eukaryotes involves either mitosis or, in the case of sex cells, meiosis. Mitosis involves the reproduction of a cell into two identical daughter cells. Meiosis, however, is a reduction division where a parental diploid cell produces four haploid gametes. Upon fusion, two haploid gametes (in humans the sperm and the egg) will result in one diploid zygote. In this activity you will track chromosomes through meiosis using colored beads.
Experiment 1
Questions
1. Why is crossing over important in heredity? (10 points)
2. Provide two ways that meiosis I and meiosis II are different. (10 points)
3. (10 points)
a. In the lab, how many chromosomes were present in each cell when meiosis I started?
b. How many chromosomes were present in each daughter cell at the end of meiosis II?
4. If humans have 46 chromosomes in each of their body cells, determine how many chromosomes you would expect to find in the following (10 points):
Sperm:
Egg:
Daughter cell from mitosis:
Daughter cell from meiosis II:
5. Why is it necessary to reduce the chromosome number of gametes, but not of other cells of an organism? (10 points)
41
Meiosis
Lab 4
42
Lab 4: Meiosis
43
Introduc on
Meiosis only occurs in organisms that reproduce sexually. The process generates haploid (1n) cells
called gametes (sperm cells in males and egg cells in fe-
males), or spores in some plants, fungi, and pro sts, that
contain one complete set of chromosomes. Haploid cells
fuse together during fer liza on to form a diploid cell with
two copies of each chromosome (2n).
Genes are the units of heredity that have speciÞc loci
(loca ons) on the DNA strand and code for inheritable
traits (such as hair color). Alleles are alterna ve forms of the same gene (brown vs. blue eyes). Homol-
ogous chromosomes contain the same genes as each other but o en di erent alleles. Non-sex cells
(e.g. bone, heart, skin, liver) contain two alleles (2n), one from the sperm and the other from the egg.
Mitosis and meiosis are similar in many ways. Meiosis, however, has two rounds of division—meiosis I
and meiosis II. There is no replica on of the DNA between meiosis I and II. Thus in meiosis, the parent
cell produces four daughter cells, each with just a single set of chromosomes (1n).
Meiosis I is the reduc on division– the homologous pairs of chromosomes are separated so that each
daughter cell will receive just one set of chromosomes. During meiosis II, sister chroma ds are sepa-
rated (as in mitosis).
Concepts to explore:
Meiosis
Diploid cells
Haploid cells
...
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2. (1)
The Cell Cycle:
a. What is the Cell Cycle? Cell Phases in which the cell grows/copies itself and divides.
b. The Phases G1 Phase, G1 Checkpoint, S Phase, G2 Phase, G2 Checkpoint, M Phase
c. You should be able to identify the phases in the above diagram.
i. Which chunk is the G1 Phase?
ii. Which chunk is the S Phase?
iii. Which chunk is the G2 Phase?
iv. Which chunk is the M Phase?
v. Which chunks make up Interphase?
vi. Where would the G1 Checkpoint be at?
vii. Where would the G2 Checkpoint be at?
d. What Happens During the Phases?
i. G1 Phase = Cell grows and copies its organelles.
ii. G1 Checkpoint = The cell checks to make sure it is growing and copying things
correctly.
iii. S Phase = Cell copies its DNA.
iv. G2 Phase = Cell continues growing and copying its organelles.
v. G2 Checkpoint = The cell checks to makesure the DNA was copied correctly.
3. vi. M Phase = Cell Divides (via Mitosis or Meiosis)
vii. *INTERPHASE = G1 Phase + S Phase + G2 Phase
(2)
Mitosis:
a. Type of Cell = Non Sex = Somatic
b. What Happens With The Genetic Information?
i. Diploid Diploid
ii. 2n 2n
iii. Exact Copy is Made (New Cells are the same as the Original Cell)
iv. In Humans: Start with 46 chromosomes or 23 pairs End with 46 chromosomes or 23
pairs
c. The Phases Prophase, Metaphase, Anaphase, Telophase, Cytokinesis
d. You should be able to identify the phases in the above diagram.
i. Which phase is Prophase?
ii. Which phase is Metaphase?
iii. Which phase is Anaphase?
iv. Which phase is Telophase?
v. What order would the pictures go in?
e. What Happens During The Phases?
i. Prophase = Nucleus dissolves, chromosomes form
4. ii. Metaphase = Pairs of sister chromatids line up at the metaphase plate
iii. Anaphase = Sister chromatids separate to opposite sides of the cell
iv. Telophase = Nuclei reform, chromosomes unwind
v. Cytokinesis = Cytoplasm splits, cell membrane reforms, end up with 2 cells
(3)
Meiosis:
a. Type of Cell = Sex Cell = Gamete
b. What Happens With The Genetic Information?
i. Diploid Haploid
ii. 2n 1n
iii. Genetic information is cut in ½
iv. The new cells are genetically diverse
v. In Humans: Start 46 chromosomes End 23 chromosomes
c. The Phases Prophase-1, Metaphase-1, Anaphase-1, Telophase-1, Cytokinesis-1
d. The Phases Prophase-2, Metaphase-2, Anaphase-2, Telophase-2, Cytokinesis-2
5. e. You should be able to identify the phases in the above diagram.
i. Which phases contain homologous pairs of chromosomes?
ii. Which phases contain sister chromatids?
iii. Which phase would involve crossing over?
iv. Which phase would involve the Law of Segregation?
v. Which phase would involve the Law of Independent Assortment?
vi. Which pictures/cells could represent gametes or sperm/egg cells?
vii. Do you notice anything odd / unique about the sex cells produced at the end of this
process of meiosis?
f. What Happens During The Phases?
i. Prophase-1 = Nucleus dissolves and chromosomes form
ii. Metaphase-1 = Crossing Over & Homologous Pairs of Chromosomes line up at
metaphase plate
iii. Anaphase-1 = Homologous Pairs of Chromosomes separate
iv. Telophase-1 = Homologous Pairs of Chromosomes are fully separated
v. Cytokinesis-1 = Cytoplasm splits & End with 2 cells
vi. Metaphase-2 = Pairs of Sister Chromatids line up at metaphase plate
vii. Anaphase-2 = Law of Segregation & Law of Independent Assortment & Sister
Chromatids separate
viii. Telophase-2 = Nuclei reform and Chromosomes unwind
ix. Cytokinesis-2 = Cytoplasm splits & End with 4 Haploid Cells
g. Special Meiosis Stuff
i. Crossing Over:
1. When nearby chunks of chromosomes swap chunks of DNA/genes.
2. Increases genetic variation.
ii. Law of Segregation:
1. Chromosomes separate so that the different variations of genes split up into
different cells.
iii. Law of Independent Assortment:
1. Chromosomes separate completely randomly, and independently of all other
chromosomes and their movement.
6. (4)
Types of Reproduction:
a. Sexual Reproduction
i. 2 Parents
ii. Offspring are genetically diverse and unique
iii. Takes a lot of time and effort to produce offspring
b. Asexual Reproduction
i. 1 Parent
ii. Offspring are genetically identical to parent and each other
iii. Very efficient
iv. Types = Budding and Binary Fission
1. Binary Fission = Cell makes a copy of itself and divides in two.
2. Bacterial Conjugation = When bacteria exchange extra chunks of DNA
(plasmids), which can increase antibiotic resistance.
(5)
Cancer:
a. The uncontrolled growth of malfunctioning cells.
b. Caused by cells making it past the check points with errors.
7. (4)
Types of Reproduction:
a. Sexual Reproduction
i. 2 Parents
ii. Offspring are genetically diverse and unique
iii. Takes a lot of time and effort to produce offspring
b. Asexual Reproduction
i. 1 Parent
ii. Offspring are genetically identical to parent and each other
iii. Very efficient
iv. Types = Budding and Binary Fission
1. Binary Fission = Cell makes a copy of itself and divides in two.
2. Bacterial Conjugation = When bacteria exchange extra chunks of DNA
(plasmids), which can increase antibiotic resistance.
(5)
Cancer:
a. The uncontrolled growth of malfunctioning cells.
b. Caused by cells making it past the check points with errors.