Meiosis produces haploid gametes from diploid cells for sexual reproduction. It involves two nuclear divisions and results in four haploid daughter cells, each with half the number of chromosomes as the original parent cell. This ensures genetic variation between offspring, which is the raw material for evolution. During meiosis I, homologous chromosomes pair and may exchange genetic material through crossing over. The homologous chromosomes then separate, followed by the second meiotic division where sister chromatids separate, resulting in four haploid cells each with a unique combination of genes.
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The slides contain all about meiosis. in this slides i collected all information about meiosis. which is useful for everyone.
so watch these slides and comment for any problems.
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â Male and female gametes fuse together during fertilization to form a zygote. The chromosome number is halved during the formation of gametes by the process of meiosis. This maintains the chromosome number generations after generations. Meiosis leads to genetic diversity which is very essential for evolution.
For the IB Biology course. If you want the editable pptx file, please make a donation to one of my chosen charities. More information here: http://sciencevideos.wordpress.com/about/biology4good/
The slides contain all about meiosis. in this slides i collected all information about meiosis. which is useful for everyone.
so watch these slides and comment for any problems.
thanks
â Male and female gametes fuse together during fertilization to form a zygote. The chromosome number is halved during the formation of gametes by the process of meiosis. This maintains the chromosome number generations after generations. Meiosis leads to genetic diversity which is very essential for evolution.
Lab TemplateWeek 4 MeiosisSubmitted by your name here.docxDIPESH30
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Lab Template
Week 4: Meiosis
Submitted by: <your name here>
As you complete the lab, record your answers in this template. Save the document as LastName_FirstName_BIO1020_W4A3, and submit it to the Dropbox. Full lab instructions and the rubric with which you will be evaluated can be found in the online classroom.
Activity
Cellular reproduction in Eukaryotes involves either mitosis or, in the case of sex cells, meiosis. Mitosis involves the reproduction of a cell into two identical daughter cells. Meiosis, however, is a reduction division where a parental diploid cell produces four haploid gametes. Upon fusion, two haploid gametes (in humans the sperm and the egg) will result in one diploid zygote. In this activity you will track chromosomes through meiosis using colored beads.
Experiment 1
Questions
1. Why is crossing over important in heredity? (10 points)
2. Provide two ways that meiosis I and meiosis II are diďŹerent. (10 points)
3. (10 points)
a. In the lab, how many chromosomes were present in each cell when meiosis I started?
b. How many chromosomes were present in each daughter cell at the end of meiosis II?
4. If humans have 46 chromosomes in each of their body cells, determine how many chromosomes you would expect to find in the following (10 points):
Sperm:
Egg:
Daughter cell from mitosis:
Daughter cell from meiosis II:
5. Why is it necessary to reduce the chromosome number of gametes, but not of other cells of an organism? (10 points)
41
Meiosis
Lab 4
42
Lab 4: Meiosis
43
Introduc on
Meiosis only occurs in organisms that reproduce sexually. The process generates haploid (1n) cells
called gametes (sperm cells in males and egg cells in fe-
males), or spores in some plants, fungi, and pro sts, that
contain one complete set of chromosomes. Haploid cells
fuse together during fer liza on to form a diploid cell with
two copies of each chromosome (2n).
Genes are the units of heredity that have speciĂc loci
(loca ons) on the DNA strand and code for inheritable
traits (such as hair color). Alleles are alterna ve forms of the same gene (brown vs. blue eyes). Homol-
ogous chromosomes contain the same genes as each other but o en di erent alleles. Non-sex cells
(e.g. bone, heart, skin, liver) contain two alleles (2n), one from the sperm and the other from the egg.
Mitosis and meiosis are similar in many ways. Meiosis, however, has two rounds of divisionâmeiosis I
and meiosis II. There is no replica on of the DNA between meiosis I and II. Thus in meiosis, the parent
cell produces four daughter cells, each with just a single set of chromosomes (1n).
Meiosis I is the reduc on divisionâ the homologous pairs of chromosomes are separated so that each
daughter cell will receive just one set of chromosomes. During meiosis II, sister chroma ds are sepa-
rated (as in mitosis).
Concepts to explore:
Meiosis
Diploid cells
Haploid cells
...
1. Of the following, which is a difference between prokaryotic and e.pdfarchanadesignfashion
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1. Of the following, which is a difference between prokaryotic and eukaryotic cells?
A. Eukaryotic cells have a nuclear envelope surrounding the genetic material, whereas
prokaryotes have no nucleus.
B. Prokaryotic cells have multiple paired chromosomes, but eukaryotic cells have
only one.
C. Prokaryotic cells have linear DNA, whereas eukaryotes have circular DNA.
D. Eukaryotes have histone proteins, whereas prokaryotes do not.
E. Plasmids contain some genes for eukaryotes, whereas organelles contain some
genes for prokaryotes.
2. Which of the following are fundamental events that must take place in cell reproduction?
A. A cell\'s genetic information must be copied.
B. The copies of the genetic information must be separated from one another.
C. The cell must divide.
D. All of the above are fundamental events that must take place in cell
reproduction.
3. What are three essential structural elements of a functional eukaryotic chromosome?
A. Histone proteins, spindle fibers, and a pair of telomeres
B. Origins of replication, chromatids, and kinetochores
C. A centromere, a pair of telomeres, and origins of replication
D. A centromere, chromatids, and kinetochores
E. Spindle fibers, kinetochores, and chromatids
4. The chromosomal structures that serve as the attachment point for spindle fibers are the
_____________________.
A. telomeres
B. origins of replication
C. centromeres
D. kinetochore proteins
E. histone proteins
5. The natural ends of eukaryotic chromosomes that serve to stabilize the ends of the
chromosomes are the ______________________.
A. telomeres
B. origins of replication
C. centromeres
D. kinetochore proteins
E. histone proteins
6. _______________ is the part of interphase within the cell cycle where the cell growth and
protein synthesis necessary for cell division and DNA replication take place.
A. G1
B. S
C. G2
D. M
E. Telophase
7. __________________ is the part of interphase within the cell cycle where additional
biochemical reactions take place preparing the cell for mitosis.
A. G1
B. S
C. G2
D. M
E. Telophase
8. __________________ is the part of interphase within the cell cycle where DNA replication
takes place.
A. G1
B. S
C. G2
D. M
E. Telophase
9. What are checkpoints?
A. Key transition points in the cell cycle that lead to cancer
B. Periods during the cell cycle that ensure all cellular components are in good
working order
C. Transition points during the process of replication that allow DNA repair
D. The last process that occurs before a cell divides
E. Critical points that ensure correct and complete cytokinesis
10. What is the stage in mitosis when sister chromatids separate at the centromere and move to
opposite poles of the cell.
A. Prophase
B. Prometaphase
C. Metaphase
D. Anaphase
E. Telophase
11. What is the stage of mitosis where the chromosomes are arranged on the equatorial plane of
the cell.
A. prophase
B. prometaphase
C. metaphase
D. anaphase
E. telophase
12. What is the stage of mitosis where the chromosomes ini.
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Meiosis
1. MEIOSIS
Unlike single celled prokaryotes, most organisms are diploid and multicellular.
At a particular time in their life cycle certain cells will differentiate, via
meiosis, into haploid cells. During sexual reproduction two haploid cells
called gametes will unite, thus restoring the diploid chromosome number in the
next generation. Meiosis is especially important because it produces genetic
variation, the raw material for evolution.
I. Halving the chromosome number
A. Sexual reproduction
1. Requires gamete formation and then fusion of gametes (syngamy) to form a
zygote
a. Gamete = a sex cell (sperm or egg)
b. Zygote = first diploid cell resulting from syngamy (fertilization)
2. If gametes contained same number of chromosomes as body cells, doubling
would soon fill cells
B. Life cycles
1. Life cycle refers to all reproductive events between one generation
and next
2. Mitosis = nuclear division that maintains a constant chromosome
number
3. Meiosis = nuclear division reducing chromosome number from diploid
(2n) to haploid (n) number
4. Meiosis occurs at different points during life cycle of various
organisms
C. Three basic types of life cycles:
1. gametic meiosis - meiosis give rise to gametes which fuse together
in syngamy (fertilization). Characteristic of animals and some types of algae.
Therefore, in animals, sexual reproduction involves a regular alternation
between meiosis and syngamy.
2. sporic meiosis - in true plants (and some algae) meiosis results in
the production of haploid spores, cells that can grow directly into a new
haploid individual. Therefore, in plants there is a regular alternation of
generations between haploid and diploid individuals.
a. In most plants meiosis takes place within flowers.
3. zygotic meiosis - haploid individuals (or cells) fuse to form a
diploid zygote which immediately undergoes meiosis. This is the simplest type
of life cycle and occurs in unicellular haploid organisms such as some algae
and all fungi.
D. Chromosomes occur in homologous pairs
1. In a diploid cell, chromosomes occur as pairs
a. Each set of chromosomes is a homologous pair; each member is a homologous
chromosome or homologue
2. Homologous chromosomes - corresponding chromosomes, one from each parent,
which contain the same genes
b. Homologues look alike; they have same length and centromere position; have
similar banding pattern human karyotype
c. A locus (location) on one homologue contains the same types of gene which
occur at the same locus on the other homologue
2. Chromosomes duplicate just before nuclear division
a. Duplication produces two identical parts called sister chromatids, held
together at centromere
3. One member of each homologous pair is inherited from either male or female
parent; one member of each homologous pair is placed in each sperm or egg
II. Overview of meiosis
A. Purpose of Meiosis
1. Meiosis keeps chromosome number constant across the generations
2. Makes sure that each gamete contains only one member of each homologous pair
B. Meiosis has two divisions
1. Since meiosis involves two nuclear divisions it produces four haploid
daughter cells; each, containing half the total number of chromosomes as the
diploid parent nucleus
2. Meiosis I - the first nuclear division
a. Prior to meiosis I, DNA replication occurs and each chromosome has two
sister chromatids
b. During meiosis I, homologous chromosomes pair; come together and line up in
synapsis
c. During synapsis, the two sets of paired chromosomes lay alongside each other
as bivalents
d. While paired up the chromosomes have equal exchanges of genetic material;
this is called crossing over
e. After crossing-over occurs, sister chromatids of a chromosome are no longer
identical
3. Meiosis II - second nuclear division, nearly identical to mitosis
a. No replication of DNA needed between meiosis I and II because chromosomes
were already doubled
b. During meiosis II, centromeres divide; daughter chromosomes derived as
sister chromatids separate
c. Chromosomes in the four daughter cells have only one chromatid
C. Crossing-over produces genetic variation, the raw material for evolution
1. Crossing-over results in exchange of genetic material between nonsister
chromatids
3. 2. Due to crossing-over, daughter chromosomes derived from sister chromatids
have different mix of genes
PHASES OF MEIOSIS
I. Prophase I
A. Nucleolus disappears; nuclear envelope fragments; and spindle fibers
assemble
B. Homologous chromosomes undergo synapsis forming bivalents; crossing-over
may occur at this time in which case sister chromatids are no longer identical
C. Chromatin condenses and chromosomes become visible
II. Metaphase I
A. Bivalents independently align themselves at the equatorial plane
(metaphase plate)
B. This independent assortment during metaphase I is another form of
genetic recombination; produces more genetic variation
C. The different possibilities can be calculated using the formula 2n
where n = haploid chromosome number. E.g. in humans 8,388,608 different ways
homologous pairs can line up (223)
D. Note centromeres are on opposite sides of the equatorial plane
III. Anaphase I
A. The homologues of each bivalent separate and move toward opposite poles
B. Each chromosome still has two chromatids
C. Note the centromeres do not divide
IV. Telophase I
A. Only occurs in some species
B. When it occurs, the nuclear envelope reforms, nucleoli reappear and
chromosomes may decondense
V. Interkinesis
A. Period between meiosis I and meiosis II
B. No DNA replication occurs
THE SECOND MEIOTIC DIVISION IS NEARLY IDENTICAL TO MITOSIS
VI. Prophase II
A. If need be the nuclear envelope and nucleoli dissolve and chromatin
condenses into chromosomes
VII. Metaphase II
A. The chromosomes align with their centromeres on the equatorial plane
VIII. Anaphase II
4. A. Centromeres divide and daughter chromosomes move toward the poles
IX. Telophase II
A. Nuclear envelope reforms, nucleoli reappear and chromosomes decondense
B. Cytokinesis produces four haploid daughter cells
X. Comparison of meiosis and mitosis:
A. Mitosis occurs more often because it allows growth and repair of body
tissues in multicellular organisms; meiosis only occurs at certain times in the
life cycle of sexually reproducing organisms
B. DNA is replicated only once before both mitosis and meiosis; in mitosis
there is only one nuclear division; in meiosis there are two nuclear divisions
C. There is no crossing-over in mitotic prophase; there is crossing-over in
prophase I of meiosis
D. Duplicated chromosomes align on metaphase plate in mitosis; bivalents
align on the metaphase I plate
E. Sister chromatids separate to form daughter chromosomes in anaphase of
mitosis; homologous chromosomes separate in anaphase I of meiosis
F. Meiosis II is like mitosis except the meiosis nuclei are haploid
G. Mitosis produces two daughter cells; meiosis produces four daughter cells
H. In mitosis, two daughter cells have same chromosome number as parent
cell; in meiosis, four daughter cells are haploid
I. In mitosis, the daughter cells are genetically identical to each other
and to the parent cell; in meiosis, the daughter cells are not genetically
identical to each other or to the parent cell
XI. Significance of Meiosis
A. Meiosis produces genetic variation
1. Without meiosis, chromosome numbers would continually increase
2. Meiosis ensures daughter cells receive one of each kind of gene; precisely
halves the chromosome number
3. Independent assortment provides 2n possible combinations of chromosomes in
daughter cells
4. In humans with 23 haploid chromosomes, 2n = 223 = 8,388,608 possible
combinations.
5. Variation is added by crossing-over; if only one crossover occurs within
each bivalent, 423 or 70,368,744,000,000 combinations are possible
6. Fertilization also contributes to genetic variation; (223)2 =
70,368,744,000,000 possible combinations without crossing-over
7. With fertilization and crossing-over, (423)2 =
4,951,760,200,000,000,000,000,000,000 combinations are possible
B. Advantages of Meiosis
5. 1. Tremendous storehouse of genetic variation provides for adaptations to
changing environment
2. Asexual organisms depend primarily on mutations to generate variation