This document provides an overview of nutrition including:
- Nutrition is the science of food and its relationship to health. It includes everything that happens to food from consumption to use in the body.
- Nutrients include macronutrients like carbohydrates, fats, proteins and micronutrients like vitamins and minerals which are required in smaller amounts.
- Nutrition contributes to wellness by preventing diseases. Nutrients are obtained from foods and provide energy for bodily functions.
- Recommended dietary allowances provide guidelines for adequate intake of nutrients. A balanced diet contains variety of foods in proper proportions.
Are most abundantly distributed organic compounds.
70 kg man= protein weight constitute 12 kg
Skeleton and connective tissue contains half
Body protein and other half is intracellular.
NutritionIntroduction, Balanced Diet, Calorie, Caloric Value, Energy Content...Maryam Fida
NutritionIntroduction, Balanced Diet, Calorie, Caloric Value, Energy Content of Food, Use of Food Energy, BMR
(Lippincott Biochemistry
Chatterje Biochemistry)
Digestion and absorption of lipids ppt
what is lipid ppt
digestion of lipid ppt
phase of digestion and absorption ppt
phases of lipids ppt
digestion in mouth and stomach ppt
digestion in small intestine ppt
secretion of lipids ppt
enzyme involved in lipid digestion ppt
transportation phases of lipids ppt
principles of lipid digestion ppt
Absorption of proteins ppt
composition of protein ppt
digestion of protein ppt
Absorption of protein ppt
absorption of amino acid ppt
function of protein ppt
amino acid ppt
role enzyme ppt
Are most abundantly distributed organic compounds.
70 kg man= protein weight constitute 12 kg
Skeleton and connective tissue contains half
Body protein and other half is intracellular.
NutritionIntroduction, Balanced Diet, Calorie, Caloric Value, Energy Content...Maryam Fida
NutritionIntroduction, Balanced Diet, Calorie, Caloric Value, Energy Content of Food, Use of Food Energy, BMR
(Lippincott Biochemistry
Chatterje Biochemistry)
Digestion and absorption of lipids ppt
what is lipid ppt
digestion of lipid ppt
phase of digestion and absorption ppt
phases of lipids ppt
digestion in mouth and stomach ppt
digestion in small intestine ppt
secretion of lipids ppt
enzyme involved in lipid digestion ppt
transportation phases of lipids ppt
principles of lipid digestion ppt
Absorption of proteins ppt
composition of protein ppt
digestion of protein ppt
Absorption of protein ppt
absorption of amino acid ppt
function of protein ppt
amino acid ppt
role enzyme ppt
food intake varies with every type of individual, so here are some food tips which can keep you healthy, stay fit and delay the age occurring degeneration, though along with proper food intake exercise is must.
Basic Nutrition gives an overview of the classification of nutrients and the deficiency diseases one can develop if unable to take a balanced diet.
The knowledge can be used to promote healthy nutritional practices in the community and participate in prevention of nutrition related illnesses in adults, children, adolescents, the sick and the , elderly
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Antimicrobial stewardship to prevent antimicrobial resistanceGovindRankawat1
India is among the nations with the highest burden of bacterial infections.
India is one of the largest consumers of antibiotics worldwide.
India carries one of the largest burdens of drug‑resistant pathogens worldwide.
Highest burden of multidrug‑resistant tuberculosis,
Alarmingly high resistance among Gram‑negative and Gram‑positive bacteria even to newer antimicrobials such as carbapenems.
NDM‑1 ( New Delhi Metallo Beta lactamase 1, an enzyme which inactivates majority of Beta lactam antibiotics including carbapenems) was reported in 2008
2. INTRODUCTION
• ‘Nutrition’‐ the science of food and its
relationship to health. Nutrition has been
defined as food at work in the body.
• Nutrition includes everything that happens to
food from the time it is eaten until it is used
for various functions in the body.
3. • Dietetics is the practical application of the
principles of nutrition; it includes the planning
of meals for the well and the sick.
• Adequate, optimum and good nutrition are
expressions used to indicate that the supply of
the essential nutrients is correct in amount
and proportion.
4. Why is Nutrition Important?
• Nutrition contributes to wellness.
Wellness: the absence of disease
Physical, emotional, and spiritual health
• Critical components of wellness:
Nutrition
Physical activity
• Nutrition can prevent disease.
Nutrient deficiency diseases: scurvy, goitre, rickets
5. Nutrients
Organic and inorganic complexes contained in food.
The word nutrient or “food factor” is used for specific dietary constituents
such as proteins, vitamins and minerals.
They are broadly divided in to:
Macronutrients:
Proteins
Fats
Carbohydrates
Micronutrients:
Vitamins
Minerals
Water
6. What Are Nutrients?
• Macronutrients: nutrients required in
relatively large amounts.
Provide energy to our bodies
Carbohydrates, fats and oils, proteins
• Micronutrients: nutrients required in smaller
amounts.
Vitamins and minerals
7. Energy From Nutrients
• We measure energy in kilocalories (kcal).
• Kilocalorie: amount of energy required to raise
the temperature of 1g of water by 1oC.
• On food labels, “calorie” actually refers to
kilocalories.
• The calorific value : energy density of nutrients/
energy yield per unit weight of food.
8. Carbohydrates
• Primary source of fuel for the body, especially for
the brain.
• Provide 4 kcal per gram
• Carbohydrates are found in grains (wheat, rice),
vegetables, fruits, and legumes.
• How does the body processes dietary
carbohydrates?
9. Carbohydrates –dietary fiber
• Dietary fiber:- The unavailable or indigestible
carbohydrate in the diet.
• It improves bowel motility, prevents constipation,
decreases reabsorption of bile acids thus
lowering cholesterol level and improves glucose
tolerance.
• It provides a feeling of fullness without
consumption of excess calories.
• Green leafy vegetables are good source of fiber.
10. Fats and oils
• Fats and oils are composed of lipids,
molecules that are insoluble in water
• Provide 7 kcal per gram.
• An important energy source during rest or low
intensity exercise.
• Found in butter, margarine, vegetable oils.
• How does the body processes dietary fats?
11. Proteins
• Proteins are chains of amino acids.
• Proteins can supply 4 kcal of energy per gram, but
are not a primary energy source.
• Proteins are an important source of nitrogen.
• Proteins are important for
• Building cells and tissues, Maintaining bones,
Repairing damage, Regulating metabolism
• Protein sources include meats, dairy products,
seeds, nuts, and legumes.
• How does the body processes dietary proteins?
12. Vitamins
• Vitamins: organic molecules that assist in
regulating body processes.
• Vitamins are micronutrients that do not
supply energy to our bodies.
Fat-soluble vitamins: Vitamins A, D, E and K
Water-soluble vitamins: Vitamin C and the B
vitamins
13. Minerals
• Minerals: inorganic substances required for
body processes.
• Minerals include sodium, calcium, iron,
potassium, and magnesium.
• Minerals have many different functions such
as fluid regulation, bone structure, muscle
movement, and nerve functioning.
14. Water
• Water is a critical nutrient for health and
survival.
• Water is involved in many body processes:
– fluid balance nutrient transport
– nerve impulses removal of wastes
– muscle contractions, chemical reactions
– many, many more…
15. Recommended Dietary Allowances
or Intakes (RDA or RDI)
• The average daily intake level required to
meet the needs of 97 – 98% of people in a
particular category
• The RDA of a nutrient is the amount (of that
nutrient) sufficient for the maintenance of
health in nearly all people.
16. Recommended Dietary Allowances
• These are the estimates of nutrient intakes
which individuals in a population group need
to consume to ensure that the physiological
needs of all subjects in that population are
met.
• It is not used for defining the energy
requirement, as any excess of energy intake is
as undesirable as its inadequate intake. Hence
for defining the RDA of energy only the
average requirement is considered.
17. Balanced Diet
• The diet which contains variety of foods in
such quantities and proportions that the need
for energy, amino acids, vitamins, minerals,
fats, carbohydrates & other nutrients is
adequately met for maintaining health, vitality
and general well‐being and also make a small
provision for extra nutrient to withstand short
duration of leanness.
18.
19. Respiratory quotient(RQ)
• It is defined as the ratio of volume of CO2 (L/g)
produced to the oxygen (L/g) consumed (during
oxidation of foodstuffs).
• RQ of
– Carbohydrate - 1
– Fats - 0.7
– Proteins - 0.8
• RQ falls when the utilization of fat increases
in relation to carbohydrates
like: in diabetes mellitus
20. Determination of RQ
• Done by open circuit method
• The subjects breaths in the atmospheric air of
known composition.
• The expired air is collected in a rubber bag or
spirometer.
• The volume of expired air, the O2 content &
CO2 content are measured.
• RQ is calculated by using the formula.
Volume of CO2 produced
RQ =
Volume of O2 used
21. Utilization of energy in normal person
Three process to meet fuel demand of the
body…….
• Basal metabolic rate(BMR)
• Specific dynamic action(SDA)
• Physical activity
22. Basal metabolic rate(BMR)
• It is the energy required by an awake
individual during complete physical and
mental rest.
• Minimum energy to maintain life or sustain
vital functions like working of heart,
circulation, brain function, respiration etc.
• The metabolic rate during sleep is less than
BMR
23. Measurement of BMR
• BMR is measured directly by the heat evolved,
or indirectly by the volume of oxygen
consumed & CO2 evolved per unit
• Prerequisite conditions:
Post-absorptive state
Mental & physical relaxation
Person is awake
Temperature maintained at 20-25°C
Supine position.
24. Measurement:
• The BMR is determined either by the
apparatus of Benedict & Roth (closed circuit
device) or by the Douglas bag method (open
circuit device).
• By Benedict-Roth method, the volume of O2
consumed (recorded on a graph paper) by the
subject for a period of 2-6 minutes under
basal conditions is determined.
25. Calculation of energy consumption
The energy consumed is calculated from oxygen
consumption.
The oxygen consumed per hour is multiplied by
constant 4.825 calories.
One litre of oxygen consumption is equivalent to
4.825 calories, when RQ of diet is 0.82.
26. • For the calculation of body surface area, the
simple formula by Du Bois and Du Bois is used.
• Body surface area =H0.725 x W0.425 x 71.84
A = H0.725 x W0.425 x 71.84
A = Surface area in cm2
H = Height in cm
W = Weight in kg.
27. Normal values
BMR is expressed as cal/sq.m/hr
• Adult males: 38 cal/sqm/hr
• Adult females: 33 cal/sqm/hr
The average body surface area for Indian
males is 1.62 sqm
For females = 1.4 sqm
28. Factors affecting BMR
• Surface area:
BMR is directly proportional to surface area.
Surface area is related to weight & height.
• Sex:
Men have higher (about 5%) BMR than women.
Due to the higher proportion of lean muscle mass
in men.
• Age:
In infants & growing children, with lean muscle
mass, the BMR is higher.
In adults, BMR decreases at the rate of about 20%
per decade of life.
29. • Physical activity:
BMR is increased in persons (athletes) with
regular exercise.
Due to increase in body surface area.
• Hormones:
Thyroid hormones (T3 & T4) have a
stimulatory effect on the metabolism of the body &
BMR.
Epinephrine, cortisol, growth hormone & sex
hormones increase BMR.
30. • Environment:
In cold climates, the BMR is higher
compared to warm climates.
• Starvation:
During the periods of starvation, the
energy intake has an inverse relation with
BMR, a decrease up to 50%
31. • Fever:
Fever causes an increase in BMR.
An elevation by more than 10% in BMR is
observed for every 1°C rise in body
temperature.
• Disease states:
BMR is elevated in various infections,
leukemias, polycythemia, cardiac failure, HTN.
In Addison's disease BMR is lowered
32. Significance of BMR
• BMR is important to calculate the calorie
requirement of an individual & planning of diets.
• Determination of BMR is useful for the
assessment of thyroid disorders.
• BMR is increased in thyrotoxicosis
(hyperthyroidism).
• BMR is decreased in hypothyroidism.
33. Specific dynamic action (SDA)
• The phenomenon of the extra heat production
by the body, over and above the calculated
caloric value, when a given food is metabolized
by the body, is known as specific dynamic action
(SDA).
• It is also known as calorigenic action or
thermogenic action or thermic action (effect) of
food.
34. SDA for different foods
SDA for different foods:
For a food containing 25 g of protein, the heat
production from the caloric value is 100 Cal
(25 x 4 Cal).
When 25 g protein is utilized by the body, 130
Cal of heat is liberated.
The extra 30 Cal is the SDA of protein.
35. SDA for protein, fat and carbohydrate 32%, 13% & 5%,
• Proteins possess the highest SDA while carbohydrates
have the lowest.
SDA for mixed diet:
• The presence of fats & carbohydrates reduces the SDA
of proteins.
• Fats are most efficient in reducing SDA of foodstuffs.
• For a regularly consumed mixed diet, the SDA is around
10%
36. Significance of SDA
• For the utilization of foods by the body,
certain amount of energy is consumed from
the body stores.
• Expenditure by the body for the utilization of
foodstuffs.
• It is the highest for proteins (30%) & lowest for
carbohydrates (5%) & for mixed diet 10%
37. • Additional 10% calories should be added to
the total energy needs (of the body) towards
SDA.
• The higher SDA for protein indicates that it is
not a good source of energy
38. Mechanism of SDA
• SDA of foods is due to the energy required for
digestion, absorption, transport, metabolism and
storage of foods in the body.
• The SDA of proteins is primarily to meet the
energy requirements for deamination, synthesis
of urea, biosynthesis of proteins, synthesis of
triacylglycerol (from carbon skeleton of amino
acids).
39. • Phenylalanine, glycine and alanine increase
the SDA.
• The SDA of carbohydrates is attributed to the
energy expenditure for the conversion of
glucose to glycogen.
• Fat, the SDA may be due to its storage,
mobilization and oxidation.
40. Consumption of protein rich diet cold climates:
• In cold climates, diet rich in proteins is
recommended, it helps to maintain the body
temperature.
• Due to its high SDA, liberates extra heat.
41. Physical activity
• The energy requirement depend on the
occupation, physical activity and lifestyle of
the individual.
Light worker (teachers, doctors) 30-40%BMR
Moderate worker (housewives, students) 40-50% BMR
Heavy work (labourers) 50-60% BMR
Very heavy work (workers & rickshaw
pullers)
60-100% BMR
42. Energy requirement of men
• Individual with light work about 60% of the
calories are spent towards BMR, about 30%
for physical activity & about 10% to take care
of the SDA.
Light work 2,200 – 2,500 Cal/day
Moderate work 2,500 – 2,900 Cal/day
Heavy work 2,900 – 3,500 Cal/day
Very heavy work 3,500 – 4,000 Cal/day
43. Environmental temperature
• Low temperature increases energy expenditure
by inducing shivering & non shivering
thermogenesis
• Shivering provides heat by increasing muscle
activity in response to cold stress.
• Non-shivering thermogenesis also produce heat.
• It is due to brown adipose tissue.
• It is stimulated by epinephrine &
norepinephrine.
44. Nitrogen balance
• Nitrogen balance: the dietary intake (I) equals the
daily loss through urine(U), Feces(F) and skin(S).
I=U+F+S
• Nitrogen intake occurs through proteins/AA
Negative nitrogen balance:- When excretion
exceeds intake
Positive nitrogen balance:- intake exceeds
excretion.
Nitrogen equilibrium: seen in normal individual
where intake equals excretion.
46. Assessment of nutritional values of
Proteins
• Protein efficiency ratio (PER)
• Biological Value(BV)
• Net protein utilization (NPU)
• Chemical score
47. Protein efficiency ratio (PER)
• PER is represented by gain in the weight of
rats per gram protein ingested
gain in body weight (g)
PER =
Protein ingested(g)
48. Biological Value(BV)
• BV is the percentage of absorbed nitrogen
retained by the body
nitrogen retained
BV = x 100
nitrogen absorbed
49. • Suppose 127 mg of protein “A” was consumed
by a rat in a day and 4 mg is recovered in feces
and 24 mg is seen in urine
then,
amount ingested =127mg
amount absorbed=127-4=123mg
amount retained= 123-24=99mg
therefore BV = 99/123x100=81%
50. Net protein utilization (NPU)
• NPU= retained nitrogen/intake of nitrogen x100
• NPU is better index than biological value, since it
takes into account the digestibility factor
Nitrogen retained
NPU= x100
Nitrogen ingested
51. Chemical score
• This is based on the chemical analysis of protein
for composition of essential amino acids which is
the compared with a reference protein(egg
protein)
• The chemical score is defined as the ratio
between the quality as the ratio between the
quantity of the most limiting essential amino
acid in the test protein to the quantity of the
same amino acid in egg protein.
52. Mg of limiting AA/g test protein
Chemical score= x100
Mg of same AA/g egg protein
53. Limiting amino acids
• When an essential amino acid is not provided in
adequate amounts in the diet, protein synthesis is
limited to the rate at which the essential amino
acid is available.
• Essential amino acids then become limiting
amino acids.
• The first-limiting amino acid is the essential
amino acid that first become deficient in the diet.
• Lysine is typically the first-limiting amino acid in
most swine diets because the requirement of
lysine is greater relative to the amount provided
in the diet.
54. Mutual supplementation of proteins
• It is fortunate that humans have the habit of
consuming mixed diet, with different foods,
simultaneously.
• Which helps to overcome the deficiency of certain
essential AA in one food being supplemented from
others.
• This phenomenon is mutual supplementation
• Eg: wheat protein(lysine-deficient, metionine rich) with
kidney bean protein (methionine- deficient, Lysine-rich)
• Results in a protein mixture of improved biological
value.