- Early initiation of basic life support, including chest compressions and use of an automated external defibrillator, can increase the chances of survival for cardiac arrest victims.
- For adults, the chain of survival involves early CPR, defibrillation with an AED, and advanced life support. For children, preventing respiratory emergencies is the first priority.
- Proper basic life support for adults involves assessing the scene, checking breathing and pulse, calling for help, performing chest compressions and rescue breaths, and using an AED if available. For children and infants, the process is similar but with adjustments to compression depth and rate.
Basic Life support is a life saving procedure done to increase the survival of a patient suffering from any life threatening conditions like cardiac arrest, choking etc. this ppt includes BLS for children and how we can save the during cardio-respiratory arrest, choking etc.
Basic Life Support is a life saving procedure ensuring patient survival in various life-threatening conditions. It includes Chain of survival, Cardio-pulmonary Resuscitation (CPR).
Basic Life support is a life saving procedure done to increase the survival of a patient suffering from any life threatening conditions like cardiac arrest, choking etc. this ppt includes BLS for children and how we can save the during cardio-respiratory arrest, choking etc.
Basic Life Support is a life saving procedure ensuring patient survival in various life-threatening conditions. It includes Chain of survival, Cardio-pulmonary Resuscitation (CPR).
First aid: Medical care steps to do for any person suffering a sudden
illness or injury until ambulance arrives or seeking for professional medical
care to:
1. Preserve Life
2. Prevent Deterioration
3. Promote Recovery
Basic life support is a part of the first aid.
Includes: ABC management (Airway, Breathing, Circulation), CPR
(Cardiopulmonary resuscitation) and AED (Automated external
defibrillation).
88% of cardiac arrest incidents occur at home.
Effective bystander CPR that is administered immediately can double or
triple the victim's chances of survival.
Only 32% of victims receive assistance from a bystander.
CPR is a process of oxygenating heart, lung through external cardiac massage and artificial respiration until the definite medical treatment can restore the normal functioning of heart, lung and brain.
First aid: Medical care steps to do for any person suffering a sudden
illness or injury until ambulance arrives or seeking for professional medical
care to:
1. Preserve Life
2. Prevent Deterioration
3. Promote Recovery
Basic life support is a part of the first aid.
Includes: ABC management (Airway, Breathing, Circulation), CPR
(Cardiopulmonary resuscitation) and AED (Automated external
defibrillation).
88% of cardiac arrest incidents occur at home.
Effective bystander CPR that is administered immediately can double or
triple the victim's chances of survival.
Only 32% of victims receive assistance from a bystander.
CPR is a process of oxygenating heart, lung through external cardiac massage and artificial respiration until the definite medical treatment can restore the normal functioning of heart, lung and brain.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. BASIC LIFE SUPPORT
•Early initiation of BLS has been shown to increase the
probability of survival for a person experiencing cardiac arrest.
To increase the odds of surviving a cardiac event, the rescuer
should follow the steps in the Adult Chain of Survival.
•Emergencies in children and infants are not usually caused by
the heart. Children and infants most often have breathing
problems that trigger cardiac arrest. The first and most
important step of the Pediatric Chain of Survival is prevention.
3. BASIC LIFE SUPPORT
•BLS ALGORITHM FOR ADULTS-Adult chain of survival
•activation of emergency response
•perform early CPR
•defibrillate with AED(automated external defibrillator)
•advanced life support
4. BASIC LIFE SUPPORT
•BLS ALGORITHM FOR CHILDREN-Paediatric chain of survival
•prevent arrest
•activation of emergency response
•perform early CPR
•defibrillate with AED
•advanced life support
5. BASIC LIFE SUPPORT
• ONE-RESCUER BLS/CPR FOR ADULTS
Be Safe
Make sure the scene is safe • Move the person out of traffic. • Move the person out
of water and dry the person. (Drowning persons should be removed from the water
and dried off; they should also be removed from standing water, such as puddles,
pools, gutters, etc.) • Be sure you do not become injured yourself.
Assess the Person
• Shake the person, tap their shoulder hard, and talk to them loudly. •If there is no
response, position the victim on their back •With your hand on the forehead and
your fingertips under the point of the chin, gently tilt the victim’s head backwards,
lifting the chin to open the airway• Check to see if the person is breathing.
(Agonal breathing, which is occasional gasping and is ineffective, does not count
as breathing.
6. BASIC LIFE SUPPORT
Call EMS
Send someone for help or to call your emergency number and to get an
AED. • If alone, call for help while assessing for breathing and pulse.
Call for help without leaving the person.)
CPR
Begin sets of compressions and rescue breaths.
Defibrillate
• Attach the AED pads when available.
7. •An AED, or automated
external defibrillator, is used
to help those experiencing
sudden cardiac arrest. It's a
sophisticated, yet easy-to-use,
medical device that can
analyze the heart's rhythm
and, if necessary, deliver an
electrical shock, or
defibrillation, to help the
heart re-establish an effective
rhythm.
8. BASIC LIFE SUPPORT
• CPR STEPS
1.Check for the carotid pulse on the side of the neck
• feel for no more than 10 seconds.
• If you are not sure you feel a pulse, begin CPR with a cycle of 30 chest
compressions and two breaths.
2. Use the heel of one hand on the lower half of the sternum in the middle of
the chest
3. Put your other hand on top of the first hand
4. Straighten your arms and press straight down Compressions should be 2
to 2.4” (5 to 6 cm) into the person’s chest and at a rate of 100 to 120
compressions per minute.
5. Be sure that between each compression you completely stop pressing on
the chest and allow the chest wall to return to its natural position.
9. BASIC LIFE SUPPORT
6.After 30 compressions, stop compressions and open the airway by
tilting the head and lifting the chin OR. Do not perform the
head-tilt/chin-lift maneuver if you suspect the person may have a neck
injury.
7. Give a breath while watching the chest rise. Repeat while giving a
second breath. Breaths should be delivered over one second.
8. Resume chest compressions. Switch quickly between compressions
and rescue breaths to minimize interruptions in chest compressions
10.
11.
12. BASIC LIFE SUPPORT
TWO-RESCUER BLS/CPR FOR ADULTS
•Many times there will be a second person available that can act as a
rescuer.
•Direct the second rescuer to call Emergency Medical Services (EMS)
without leaving the person while you begin CPR. This second rescuer
can also find an AED while you stay with the person. When the
second rescuer returns, the CPR tasks can be shared.
13. BASIC LIFE SUPPORT
1.The second rescuer prepares the AED for use.
2. You begin chest compressions and count the compressions out loud.
3. The second rescuer applies the AED pads.
4. The second rescuer opens the person’s airway and gives rescue
breaths.
5. Switch roles after every five cycles of compressions and breaths. One
cycle consists of 30 compressions and two breaths.
6. Be sure that between each compression you completely stop
pressing on the chest and allow the chest wall to return to its natural
position
14. BASIC LIFE SUPPORT
•7.Quickly switch between roles to minimize interruptions in delivering
chest compressions.
•8. When the AED is connected, minimize interruptions of CPR by
switching rescuers while the AED analyzes the heart rhythm. If a
shock is indicated, minimize interruptions in CPR. Resume CPR as
soon as possible.
15.
16. BASIC LIFE SUPPORT
• ADULT MOUTH-TO-MASK VENTILATION
• In one-rescuer CPR, breaths should be supplied using a pocket mask, if
available.
• 1. Give 30 high-quality chest compressions.
• 2. Seal the mask against the person’s face by placing four fingers of one
hand across the top of the mask and the thumb of the other hand along the
bottom edge of the mask
• 3. Using the fingers of your hand on the bottom of the mask, open the
airway using the head-tilt/chin-lift maneuver. (Do not do this if you suspect
the person may have a neck injury) .
• 4. Press firmly around the edges of the mask and ventilate by delivering a
breath over one second as you watch the person’s chest rise
17. BASIC LIFE SUPPORT
• ADULT BAG-MASK VENTILATION IN TWO-RESCUER CPR
• If two people are present and a bag-mask device is available, the second
rescuer is positioned at the victim’s head while the other rescuer performs
high-quality chest compressions. Give 30 high-quality chest compressions.
1. Deliver 30 high-quality chest compressions while counting out loud.
• 2. The second rescuer holds the bag-mask with one hand using the thumb
and index finger in the shape of a “C” on one side of the mask to form a
seal between the mask and the face, while the other fingers open the
airway by lifting the person’s lower jaw
• 3. The second rescuer gives two breaths over one second each as you
watch the person’s chest rise.
• 4. Practice using the bag-valve-mask; it is essential to forming a tight seal
and delivering effective breaths. Quickly switch roles to minimize
interruptions.
18.
19. BASIC LIFE SUPPORT
Criteria for high-quality CPR:
• Start chest compressions (hard and fast) within 10 seconds
• Allow for complete chest recoil between compressions
• Minimize interruptions between chest compressions
• Assure that the breaths make chest rise
• Do not over-ventilate
• Assess for shockable rhythm as soon as AED available in witnessed
cardiac arrest as it is most likely a shockable rhythm.
20. BASIC LIFE SUPPORT
•AED STEPS
• 1. Retrieve the AED a. Open the case. b. Turn on the AED. 2. Expose
the person’s chest. a. If wet, dry chest. b. Remove medication
patches.
•3. Open the AED pads a. Peel off backing. b. Check for pacemaker or
internal defibrillator.
•4. Apply the pads. a. Apply one pad on upper right chest above the
breast. b. Apply the second pad on lower left chest below the armpit.
•5. Ensure the wires are attached to the AED box. 6. Move away from
the person. a. Stop CPR. b. Clear the person to make sure no one is
touching any part of the victim.
21. BASIC LIFE SUPPORT
•If AED message reads “Shock,” a. Be sure the person is “clear” by
making sure no one is touching them. b. Press and hold the “shock”
button until the AED delivers the shock
22. BLS FOR CHILDREN
•Many similarities exist between the BLS guidelines for adults and
children. Following are the main differences between the two:
•For children, the compression to breaths ratio is 15:2 for all age
groups. The depth of compression may be different.
•For children, compress the chest at least one-third the depth of the
chest. This may be less than two inches for small children (4 -5 cm)
but will be approximately two inches for larger children (5 cm).
•• If you are the only rescuer at the scene and find an unresponsive
child, perform CPR for two minutes before you call EMS or before you
go look for an AED
23. BLS FOR INFANTS
•BLS for both children and infants is almost identical. Following are the
main differences between BLS for children and BLS for infants: •
Check the pulse in the infant using the brachial artery on the inside of
the upper arm between the infant’s elbow and shoulder.
•During CPR, compressions can be performed on an infant using two
fingers, if only one rescuer; or with two thumb-encircling hands, if
there are two rescuers and rescuer’s hands are big enough to go
around the infant’s chest.
• Compression depth should be one-third of the chest depth; for most
infants, this is about 1.5 inches (4 cm).
24. BASIC LIFE SUPPORT
• If you are the only rescuer at the scene and find an unresponsive
infant, perform CPR for two minutes before calling EMS or using an
AED.
• In infants, primary cardiac events are not common. Usually, cardiac
arrest will be preceded by respiratory problems. Survival rates improve
when you intervene with respiratory problems as early as possible.
•Remember that prevention is the first step in the Pediatric Chain of
Survival.
25. BASIC LIFE SUPPORT
•ONE-RESCUER BLS FOR INFANTS
•If you are alone with the infant at the scene, do the following:
•1. Tap the heel of their foot and talk loudly at the infant to determine
if they are responsive.
•2. Assess if they are breathing while simultaneously checking for the
infant’s brachial pulse for 5 but no more than 10 seconds. If the infant
does not respond and is not breathing (only gasping), yell for help.
•3. If someone responds, send the second rescuer to call EMS and get
an AED.
26. BASIC LIFE SUPPORT
•If you cannot feel a pulse (or if you are unsure), begin CPR by doing
15 compressions followed by two breaths(15:2). If you can feel a
pulse but the rate is less than 60 beats per minute, begin CPR. This
rate is too slow for an infant.
•To perform CPR on an infant, do the following: a. Be sure the infant is
face-up on a hard surface. b. Using two fingers, perform
compressions in the center of the infant’s chest ; do not press on the
end of the sternum as this can cause injury to the infant. c.
Compression depth should be about 1.5 inches (4 cm) and 100-120
compressions per minute.
•5. Perform CPR for about two minutes (using cycles of 15
compressions and two breaths). If help has not arrived, call EMS and
get an AED.
27. BASIC LIFE SUPPORT
•TWO-RESCUER BLS FOR INFANTS
• If you are not alone with the infant at the scene, do the following:
•1. Tap the bottom of their foot and talk loudly at the infant to
determine if they are responsive.
•2. If the infant does not respond, have the second rescuer call EMS
and get an AED
•3. Assess if they are breathing while simultaneously feeling for the
infant’s brachial pulse for 5 but no more than 10 seconds.
•4. If you cannot feel a pulse (or if you are unsure), begin CPR by doing
15 compressions followed by two breaths. If you can feel a pulse but
the rate is less than 60 beats per minute, begin CPR. This rate is too
slow for an infant.
28. BASIC LIFE SUPPORT
•5.When the second rescuer returns, begin CPR by performing 15
compressions by one rescuer and two breaths by the second rescuer.
If the second rescuer can fit their hands around the infant’s chest,
perform CPR using the two thumb-encircling hands method. Do not
press on the bottom end of the sternum as this can cause injury to
the infant.
•6. Compressions should be approximately 1.5 inches (4 cm) deep and
at a rate of at least 100-120 per minute.
•7. Use and follow AED prompts when available while continuing CPR
until EMS arrives or until the infant’s condition normalizes.
29.
30. BASIC LIFE SUPPORT
AED FOR CHILDREN AND INFANT
1.Retrieve the AED a. Open the case. b. Turn on the AED.
2. Expose the person’s chest. a. If wet, dry the chest. b. Remove any
medication patches.
3.Open the Pediatric AED pads. a. Peel off backing. b. Check for pacemaker or
implanted defibrillator.
4. Apply the pads. a. Apply one pad on the upper right chest above the
breast. For infants, apply on front of chest b. Apply the second pad on lower
left chest below the armpit. For infants, apply second pad to back 5. Ensure
wires/ probes are attached to the AED devise
6. Move away from the child. a. Stop CPR. b. Instruct others not to touch the
person.
32. NOTE: If no AED is available, OR whilst waiting for one to arrive,
continue CPR •Do not interrupt resuscitation until: •A health
professional tells you to stop OR •The victim is definitely waking up,
moving, opening eyes, and breathing normally •OR •You become
exhausted.
•If you are certain that the victim is breathing normally but still
unresponsive, place them in the recovery position
•Be prepared to restart CPR immediately if the victim becomes
unresponsive, with absent or abnormal
33. BASIC LIFE SUPPORT
NOTE: The compression rate for
all persons is always 100-120 per
minute.
BLS CAN BE DONE BY ONE PERSON,
TWO OR A TEAM.
Always have a team leader if being done by a team