The document outlines the components of the basal forebrain and their connections, detailing the orbito-frontal pre-frontal cortex, septal areas, ventral striatum, and ventral pallidum. It describes various nuclei and their roles related to the limbic system, including aspects of reward pathways and connections with the hypothalamus and amygdala. The emphasis is on anatomical structures relevant to neuroscience research, particularly in understanding conditions like schizophrenia.

1. Dr Sanjoy Sanyal
Professor and Course Director,
Neuroscience

2. Basal Forebrain Components
 OF-PFC: Orbito-Frontal Pre-Frontal Cortex
 Septal Areas:
 Cortical Areas: Para-terminal Gyrus (Adjacent to
Lamina Terminalis) and Sub-callosal (Under
Rostrum of Corpus Callosum)
 Subcortical Nuclei: Between Septum Pellucidum
and Anterior Commissure (Lateral, Medial, Posterior
Nuclei)
 Ventral Striatum: Nucleus Accumbens +
Olfactory Tubercle (Cells of Calleja)
 Ventral Pallidum: Substantia Innominata;
Including Nucleus Basalis of Meynert
 Anterior Hypothalamus: Pre-Optic Area

3. Orbito-
Frontal
PFC

4. Septal Areas and Connections

5. Ventral
Striatum
Includes Nucleus
Accumbens under
Striatum (Fusion of
Head of Caudate
Nucleus with Putamen)
Also includes
Olfactory Tubercle
(Part of Allocortex
containing Cells of
Calleja in Anterior
Perforated Substance)

6. Nucleus Accumbens

7. VentralPallidum

8. Nucleus Basalis of
Meynert

9. Ventral Striato-pallidal
Tract
 Olfactory Cortex / OF-PFC / Hippocampus
 Ventral Striatum (Nucleus Accumbens +
Olfactory Tubercle)
 Ventral Pallidum (Substantia innominata, which
includes Nucleus Basalis of Meynert)
 Dorso-medial (Medio-Dorsal) Nucleus of
Thalamus

10. Septal Areas and Connections

11. Meso-Limbic / Meso-Cortical
Tract

12. Meso-Limbic / Meso-Cortical
Tract

13. Schizophrenia and Reward
Pathway

14. Hypothalamic Afferents

15. Hypothalamic Efferents

16. Limbic Connections

18. Hippocampal
Formation
Connections

20. Amygdala Connections