The document discusses the effects of early attachment experiences and trauma on brain development. It explains that neural development depends on experience and that the brain, especially the prefrontal cortex, continues developing through adolescence in response to environment. Children with Reactive Attachment Disorder often have low self-esteem and believe they are unworthy due to early experiences, and helping them develop trust and control emotional responses requires long-term specialized support. The prefrontal cortex is especially important for executive functions and emotional regulation, and experiences of neglect or trauma can negatively impact its development. The document provides strategies for supporting students with attachment difficulties.