This document provides an overview of key organic compounds found in nature including proteins, nucleic acids, lipids, and carbohydrates. It describes the basic composition and functions of these macromolecules. Proteins are made of amino acids and perform important roles such as tissue growth, biochemical reactions, hormone messaging, pH maintenance, and energy provision. Nucleic acids contain nucleotides and carry genetic material and protein coding. Lipids are composed of carbon, hydrogen, oxygen and nitrogen, are not water soluble, and store and release energy. Carbohydrates provide energy and regulate blood glucose through sugars, starches and cellulose.