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Anthelmintics 101
There are only 3 families of drugs.
BENZIMIDAZOLES
1.Fenbendazole
Safeguard®
Panacur®
2.Albendazole
Valbazen®
3.Oxybendazole
Synanthic®
MACROCYLIC
LACTONES
1. Avermectins
a) Ivermectin
Ivomec®
Primectin®
Privermectin®
b) Eprinomectin
Eprinex®
c) Doramectin
Dectomax®
2. Milbimycins
a) Moxidectin
Cydectin®
Quest®
NICOTINIC
AGONISTS
1.Imidazothiaoles
a) Levamisole
Prohibit®
2. Tetrahydropyrimidines
a) Morantel
Rumatel®
Positive Goat Pellet
Goat dewormer
b) Pyrantel
Strongid®
1 32
(1)
Benzimidazoles
(2) Macrocylic lactones (3)
NicotinicsAvermectins Milbimycins
Adult worms    
Immature worms (L4)    
Hypobiotic larvae    ?
Lung worms     +
Tape worms 
Adult liver flukes 
Coccidia
External parasites  
Persistent activity 
Safety Restricted use during
early pregnancy
++++ ++++ ++
Resistance ++++ +++ ++ +
FDA-approved Valbazen® Ivomec® Cydectin® Levamisole®
Labeled dosage 3 ml/100 lbs. 3 ml/26 lbs. 1 ml/11 lbs. 2 ml/50 lbs.
Meat withdrawal 7 days 11 days 7 days 3 days
FDA-approved anthelmintics for sheep
(1) Benzimidazoles (3) Nicotinics
SafeGuard® Valbazen® Rumatel®
Adult worms  
Immature worms (L4) 
Hypobiotic larvae 
Lung worms 
Tape worms not labeled
Adult liver flukes 
Coccidia
External parasites
Safety ++++ Restricted use during
early pregnancy
++
Resistance ++++ ++++ ?
Labeled dosage per 100 lbs. 2.3 ml 4 ml 0.44 g
Meat withdrawal 6 days 7 days 30 days
Milk withdrawal NA NA 0 days
FDA-approved anthelmintics for goats
(1) Benzimidazoles (2) Macrocylic lactones (3) Nicotinics
SafeGuard® Valbazen® Ivomec® Cydectin® Prohibit®
Adult worms     
Immature worms (L4)     
Hypobiotic larvae     ?
Lung worms      +
Tape worms  
Adult liver flukes 
Coccidia
External parasites  
Persistent activity ?
Safety ++++ Restricted use
during early
pregnancy
++++ ++++ ++
Resistance ++++ ++++ +++ ++ +
Dosage per 25 lbs. 1.1 ml 2 ml 6 ml 4.5 ml 2.7 ml
Meat withdrawal 16 days 9 days 14 days 17 days 4 days
Milk withdrawal 4 days 7 days 9 days 8 days 3 days
Extra-label anthelmintics for goats

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Anthelmintics 101 - Charts

  • 1. Anthelmintics 101 There are only 3 families of drugs. BENZIMIDAZOLES 1.Fenbendazole Safeguard® Panacur® 2.Albendazole Valbazen® 3.Oxybendazole Synanthic® MACROCYLIC LACTONES 1. Avermectins a) Ivermectin Ivomec® Primectin® Privermectin® b) Eprinomectin Eprinex® c) Doramectin Dectomax® 2. Milbimycins a) Moxidectin Cydectin® Quest® NICOTINIC AGONISTS 1.Imidazothiaoles a) Levamisole Prohibit® 2. Tetrahydropyrimidines a) Morantel Rumatel® Positive Goat Pellet Goat dewormer b) Pyrantel Strongid® 1 32
  • 2. (1) Benzimidazoles (2) Macrocylic lactones (3) NicotinicsAvermectins Milbimycins Adult worms     Immature worms (L4)     Hypobiotic larvae    ? Lung worms     + Tape worms  Adult liver flukes  Coccidia External parasites   Persistent activity  Safety Restricted use during early pregnancy ++++ ++++ ++ Resistance ++++ +++ ++ + FDA-approved Valbazen® Ivomec® Cydectin® Levamisole® Labeled dosage 3 ml/100 lbs. 3 ml/26 lbs. 1 ml/11 lbs. 2 ml/50 lbs. Meat withdrawal 7 days 11 days 7 days 3 days FDA-approved anthelmintics for sheep
  • 3. (1) Benzimidazoles (3) Nicotinics SafeGuard® Valbazen® Rumatel® Adult worms   Immature worms (L4)  Hypobiotic larvae  Lung worms  Tape worms not labeled Adult liver flukes  Coccidia External parasites Safety ++++ Restricted use during early pregnancy ++ Resistance ++++ ++++ ? Labeled dosage per 100 lbs. 2.3 ml 4 ml 0.44 g Meat withdrawal 6 days 7 days 30 days Milk withdrawal NA NA 0 days FDA-approved anthelmintics for goats
  • 4. (1) Benzimidazoles (2) Macrocylic lactones (3) Nicotinics SafeGuard® Valbazen® Ivomec® Cydectin® Prohibit® Adult worms      Immature worms (L4)      Hypobiotic larvae     ? Lung worms      + Tape worms   Adult liver flukes  Coccidia External parasites   Persistent activity ? Safety ++++ Restricted use during early pregnancy ++++ ++++ ++ Resistance ++++ ++++ +++ ++ + Dosage per 25 lbs. 1.1 ml 2 ml 6 ml 4.5 ml 2.7 ml Meat withdrawal 16 days 9 days 14 days 17 days 4 days Milk withdrawal 4 days 7 days 9 days 8 days 3 days Extra-label anthelmintics for goats