This document provides an overview of analysis of variance (ANOVA). It defines ANOVA as a statistical method used to analyze differences between two or more means. The document outlines the key terminology used in ANOVA such as grand mean, sample mean, null and alternative hypotheses, between and within group variability, F-test, F-critical value, and F-ratio. It also describes how ANOVA compares total variance between samples to variance within samples and uses the F-ratio to determine if means are significantly different based on the F-critical value. Examples of medical treatments are provided to illustrate how ANOVA can be used to determine if treatments are equally effective.