This document discusses anaplasmosis, a disease caused by Anaplasma bacteria that infects the red blood cells of ruminants. It is transmitted by ticks and insects. Clinical signs in mature cattle include fever, anemia, yellow urine, depression, rapid breathing, loss of appetite, decreased milk production, and occasional aggression. Diagnosis can be made by examining blood smears under a microscope or through serological tests. Control involves treating infected animals with antibiotics like oxytetracycline and preventing transmission by ticks and insects.

1. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
Questions

2. Introduction
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Life Cycle
Pathogenesis
Diagnosis
Control
Caused by Anaplasma
Also known as Gall Sickness
Infect RBCs
Disease of Ruminants (NonRuminants may act as carrier)
• Zoonotic Disease (Anaplasma
phagocytophilum affects WBCs)
Questions

3. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
Tropics & Subtropics
• Africa
• Middle East
• Asia
• Australia
• Southern Europe
• USA
• Central & South America
Common
Hosts
Cattle
Buffalo
Sheep
Goat
Reindeer
Human
Dog
Questions

4. Introduction
Life Cycle
Physical Vectors
• Flies
• Horse Flies
• Stable Flies
• Dear Flies
• Mosquitoes
• Instruments
• Surgical Instrumants
• Dehorning Instruments
• Castration Instruments
• Tattoo Instruments
• Hypodermic Needles
Diagnosis
Pathogenesis
Biological Vector
• Ticks
Control
Questions

5. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
Questions

6. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
Questions

7. Introduction
Life Cycle
Pathogenesis
Diagnosis
Calves Under 6
• Show no Signs or Symptoms
Moths
Up to 18
months old
• Show only Symptoms
Mature Cattle • Show Signs & Symptoms
Control
Questions

8. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
High Fever
Anemia or
Paleness
Yellowish
Urine
Depression
Rapid
Respiration
Off feed
Loss of
Production
Dehydration &
Constipation
Occasional
Aggressiveness
Incoordination
Abortions
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9. Introduction
Clinical
Signs
Life Cycle
Blood
Smears
Pathogenesis
Serological
Tests
Diagnosis
Biopsy
Control
Gene
Diagnosis
Questions

10. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
Questions

11. Introduction
Life Cycle
Pathogenesis
Diagnosis
Oxytetracycline
Chlortetracycline
Doxycycline
Rifampin
Control
Questions

12. Introduction
Life Cycle
Pathogenesis
Diagnosis
Control
Questions