Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

Questions
Introduction

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Life Cycle

Pathogenesis

Diagnosis

Control

Caused by Anaplasma
Also known as Gall Sickness
Infect RBCs
Disease of Ruminants (NonRuminants may act as carrier)
• Zoonotic Disease (Anaplasma
phagocytophilum affects WBCs)

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

Tropics & Subtropics
• Africa
• Middle East
• Asia
• Australia
• Southern Europe
• USA
• Central & South America
Common
Hosts

Cattle

Buffalo

Sheep

Goat

Reindeer

Human

Dog

Questions
Introduction

Life Cycle

Physical Vectors
• Flies
• Horse Flies
• Stable Flies
• Dear Flies
• Mosquitoes
• Instruments
• Surgical Instrumants
• Dehorning Instruments
• Castration Instruments
• Tattoo Instruments
• Hypodermic Needles

Diagnosis

Pathogenesis

Biological Vector
• Ticks

Control

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Calves Under 6
• Show no Signs or Symptoms
Moths
Up to 18
months old

• Show only Symptoms

Mature Cattle • Show Signs & Symptoms

Control

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

High Fever

Anemia or
Paleness

Yellowish
Urine

Depression

Rapid
Respiration

Off feed

Loss of
Production

Dehydration &
Constipation

Occasional
Aggressiveness

Incoordination

Abortions

Questions
Introduction

Clinical
Signs

Life Cycle

Blood
Smears

Pathogenesis

Serological
Tests

Diagnosis

Biopsy

Control

Gene
Diagnosis

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Oxytetracycline

Chlortetracycline

Doxycycline

Rifampin

Control

Questions
Introduction

Life Cycle

Pathogenesis

Diagnosis

Control

Questions

Anaplasma