The patient is a 79-year-old woman who was experiencing motor skill difficulties like trouble walking. Tests were needed to diagnose the cause, which included an EMG, MRI, blood and urine tests, and spinal tap to rule out other conditions. The diagnosis was amyotrophic lateral sclerosis (ALS), a disease that breaks down nerve cells and causes muscle disability. The only FDA-approved medication for ALS is riluzole, which may help slow progression by reducing glutamate levels in the brain that are often higher with ALS. The ice bucket challenge raised awareness for ALS by simulating symptoms of impaired speech and breathing.