1
University of
Duhok
School of Pharmacy
2
Kingdom –
Plantae
Order – Rosales
Family –
Rosaceae
Genus – Prunus
Species – P. Dulcis
PrunusPrunus
Almonds are a familiar type of nut.Almonds are a familiar type of nut.
They can beThey can be sweetsweet oror bitterbitter, depending on the, depending on the
type of tree.type of tree.
Sweet almondSweet almond (Prunus amygdalus var. dulcis)(Prunus amygdalus var. dulcis)
and does not contain poisonous chemicals.and does not contain poisonous chemicals.
Bitter almond fromBitter almond from (Prunus amygdalus var.(Prunus amygdalus var.
amara)amara) andand contain toxic chemicals.contain toxic chemicals.
4
trees about 5 m in height.
young fruit have a soft
wall
fruit ripens to form a
pitted wall or shell.
 The seeds length from
1.5 cm to 5 cm,
Odor :( benzaldehyde odor
) bland odor
Origin: Iran & Asia minor
and now cultivated in the
5
Rose color
flowers
Seeds
skin
6
Fats: unsaturated oleic, linoleic fatty acids,
and palmitic acid
Glycoside: amygdalin
Vitamins: E, (α-tocopherol), Vit B complex
(RiboflavinB2,Niacin)
Dietary fibers
Minerals:Magnesium, Phosphorus,
Calcium, Potassium
polyphenolic; flavonols (quercetin)
8
Amygdalin : poisonous cyanogenetic
glycoside found in the seeds of bitter
almonds which upon enzymatic
hydrolysis with emulsin give rise to
hydrocyanic acid(HCN), benzaldehyde,
suger.
Amygdalin enzyme emulsin + H2O
HCN +
+ benzaldehyde (V.O)
+glucose
Riboflavin :is essential for
oxidation reduction reactions in the
cell and
in cellular respiration.
Vitamin E :is the major antioxidant
in body tissues and is defense against
lipid peroxidation,
protecting cell membranes
10
Bitter almond used as sedative
due to HCN content.
Demulcent in skin-lotion.
Help in weight loss as it contain healthy
fats.
Make teeth , bone stronger.
Antioxidants fight free radical damage
Nourishes nervous system.
Relief from constipation.
Treatment of heart burn
Both varieties contain
40-55 % fixed oil
20% protein
mucilage & emulsin.
Bitter almonds
contain 2.5-4%
cyanogenic glycoside,
amygdalin.
12
Almond oils is produced
by grinding the seeds &
expressing them in a
canvas bag between
slightly heated iron
plates. the oil is then
clarified by subsidence
and filtration.
Oil is pale yellow liquid
with a slight odour &
bland, nutty taste.13
Essential oil is obtained
from the cake left after
expressing bitter
almonds. This is
macerated with water for
some time to allow for the
hydrolysis of amygdalin.
The benzaldehyde and
hydrocyanic acid are
separated by steam
distillation.14
ablution articles.
mild laxative action.
Volatile almond oil is used
as a flavouring agent.
preparing emulsion and
as vehicle for oily
injections
Cosmetics – hair and skin
creams and lotions
15
16
Sedative medications:
Phenobarbital
Diazepam
Vitamin C
Grains & Eggs
17
Trease and Evans' Pharmacognosy
16th
Edition  By William Charles Evans
Textbook of Pharmacognosy and Phytochemistry
 By Biren Shah, Avinash Seth
therapeutic Applications of Almonds
(Prunus amygdalus L):by
Dr. Hari Jagannadha Rao , Dr. Lakshmi
www.webmed.com
Almond

Almond

  • 1.
  • 2.
  • 3.
    Kingdom – Plantae Order –Rosales Family – Rosaceae Genus – Prunus Species – P. Dulcis PrunusPrunus
  • 4.
    Almonds are afamiliar type of nut.Almonds are a familiar type of nut. They can beThey can be sweetsweet oror bitterbitter, depending on the, depending on the type of tree.type of tree. Sweet almondSweet almond (Prunus amygdalus var. dulcis)(Prunus amygdalus var. dulcis) and does not contain poisonous chemicals.and does not contain poisonous chemicals. Bitter almond fromBitter almond from (Prunus amygdalus var.(Prunus amygdalus var. amara)amara) andand contain toxic chemicals.contain toxic chemicals. 4
  • 5.
    trees about 5m in height. young fruit have a soft wall fruit ripens to form a pitted wall or shell.  The seeds length from 1.5 cm to 5 cm, Odor :( benzaldehyde odor ) bland odor Origin: Iran & Asia minor and now cultivated in the 5 Rose color flowers
  • 6.
  • 7.
    Fats: unsaturated oleic,linoleic fatty acids, and palmitic acid Glycoside: amygdalin Vitamins: E, (α-tocopherol), Vit B complex (RiboflavinB2,Niacin) Dietary fibers Minerals:Magnesium, Phosphorus, Calcium, Potassium polyphenolic; flavonols (quercetin)
  • 8.
  • 9.
    Amygdalin : poisonouscyanogenetic glycoside found in the seeds of bitter almonds which upon enzymatic hydrolysis with emulsin give rise to hydrocyanic acid(HCN), benzaldehyde, suger. Amygdalin enzyme emulsin + H2O HCN + + benzaldehyde (V.O) +glucose
  • 10.
    Riboflavin :is essentialfor oxidation reduction reactions in the cell and in cellular respiration. Vitamin E :is the major antioxidant in body tissues and is defense against lipid peroxidation, protecting cell membranes 10
  • 11.
    Bitter almond usedas sedative due to HCN content. Demulcent in skin-lotion. Help in weight loss as it contain healthy fats. Make teeth , bone stronger. Antioxidants fight free radical damage Nourishes nervous system. Relief from constipation. Treatment of heart burn
  • 12.
    Both varieties contain 40-55% fixed oil 20% protein mucilage & emulsin. Bitter almonds contain 2.5-4% cyanogenic glycoside, amygdalin. 12
  • 13.
    Almond oils isproduced by grinding the seeds & expressing them in a canvas bag between slightly heated iron plates. the oil is then clarified by subsidence and filtration. Oil is pale yellow liquid with a slight odour & bland, nutty taste.13
  • 14.
    Essential oil isobtained from the cake left after expressing bitter almonds. This is macerated with water for some time to allow for the hydrolysis of amygdalin. The benzaldehyde and hydrocyanic acid are separated by steam distillation.14
  • 15.
    ablution articles. mild laxativeaction. Volatile almond oil is used as a flavouring agent. preparing emulsion and as vehicle for oily injections Cosmetics – hair and skin creams and lotions 15
  • 16.
  • 17.
  • 18.
    Trease and Evans'Pharmacognosy 16th Edition  By William Charles Evans Textbook of Pharmacognosy and Phytochemistry  By Biren Shah, Avinash Seth therapeutic Applications of Almonds (Prunus amygdalus L):by Dr. Hari Jagannadha Rao , Dr. Lakshmi www.webmed.com

Editor's Notes

  • #6 the inner part of which gradually become sclerenchymatous as
  • #11 Vitamin E is an antioxidant which prevents the LDL cholesterol becoming bad. In situations where the antioxidants like vitamin E and others are deficient in the blood the LDL cholesterol becomes oxidised and unstable, gets bad and is suppose to participate in the building up of plaques. This theory is been disputed by many authorities.
  • #12 Almonds, rich in phytosterols, fiber, and alpha-tocopherol, may act via various mechanisms to reduce cholesterol absorption and increase elimination,
  • #17 Balmandol® (liquid) –emollient for dry skin (Almond oil + paraffin ).
  • #18 Coadministration of high-dose vitamin C and almonds may result in symptoms of cyanide toxicity. Cyanide inhibited the uptake of vitamin C by human polymorphonuclear leukocytes (PMNs).