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Acid base balance
ABG
By
Aymen Alhasni
Normal Value








PH = 7.40 (7.35 – 7.45)
PaCo2 = 40 (35 – 45) mmHg
HCO3= 25 (22– 26) mmHg
PaO2 = 80– 100 mmHg
Sao2 = 92 – 96 % Cl = 100 mmol/L
Anion Gap: 12 ±2 ( Na – (HCO3 +Cl)
Delta Gap: 6 ( AG – HCO3 )
Cl/HCO3 Gap: 5 (Cl - HCO3 )
Acid. Alkaline
•
•
•
•
•
•
PH. 7.35 - 7.45
PCO2. 45. - 35
HCO3 22 - 28
. HCO3. Metabolic Acidosis
HCO3. Metabolic Alkalosis
PCO2. Respiratory Acidosis
PCO2 . Respiratory Alkalosis
3 Steps
•
•
•
Step 1: Look at: pH : Acidemia or alkalemia
Step 2: Look at: PaCO2/HCO3: Resp./Met.
Step 3: Is there Expected Compensa on
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
•
•
•
PH =7.49
HCO3 = 27
Paco2 = 28
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
• Uncompensated RESPIRATORY Alkalosis
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
•
•
•
PH. 7.21
HCO3. 15
paco2. 40
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
• Uncompensated Metabolic Acidosis
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
•
•
•
PH. 7.50
HCO3. 34
paco2. 41
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
• Uncompensated Metabolic Alkalosis
Types of compensation
•
•
•
Par al
complete
mixed
Partial
•
•
•
PH. 7.21
HCO3. 15
paco2. 40
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
•
•
•
•
•
•
Par al compensa on RESPIRATORY Alkalosis
Ph. 7.50
pco2. 25
Hco3 19
Na. 130
cl. 80
complete
complete
complete
• Compensated RESPIRATORY Alkalosis
mixed
mixed
mixed
• Mixed Metabolic Respiratoty Alkalosis
Anion Gap

•
•
•
•
•
Anion Gap: 12 ±2 ( Na – (HCO3 + Cl)
PH 7.30
pco2. 60
Hco3 30
Na 135
cl 100
PH= 7.35 _7.45 paco2 =35_45 Hco3 =22_28
• RESPIRATORY Acidosis with low AG
Thank you
The end

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Acid base balan : Acid and base balance in the human body