The Role of the Private Sector in Strengthening MLN Diagnostics Capacity in A...CIMMYT
The Role of the private sector in strengthening MLN diagnostics capacity in Africa, presented at the International Conference on “MLN Diagnostics and Management in Africa,” organized by AGRA (Alliance for Green Revolution in Africa) and CIMMYT, 12-14 May, 2015
The Role of the Private Sector in Strengthening MLN Diagnostics Capacity in A...CIMMYT
The Role of the private sector in strengthening MLN diagnostics capacity in Africa, presented at the International Conference on “MLN Diagnostics and Management in Africa,” organized by AGRA (Alliance for Green Revolution in Africa) and CIMMYT, 12-14 May, 2015
Workshop on MLN Diagnostics and Managment in AfricaCIMMYT
Current Phytosanitary Policies to Control the incidence and spread of MLN in Nigeria and Africa, presented at the International Conference on “MLN Diagnostics and Management in Africa,” organized by AGRA (Alliance for Green Revolution in Africa) and CIMMYT, 12-14 May, 2015
Presentation by Kebede Amenu, Coen van Wagenberg, Claudia Ganser, James Noah Ssemanda, Arie Havelaar, Kristine Roesel, Biruk Alemu Gemeda, Lina Mego, Donya Madjdian, Theo Knight-Jones at a stakeholder update workshop on Ethiopia food safety research projects, Addis Ababa, Ethiopia, 20 May 2021.
Boosting Uganda’s Investments in Livestock Development (2019-2023): Introduci...ILRI
Presented by Dan Tumusiime (MAAIF), Bernard Bett (ILRI), Emily Ouma (ILRI), Samuel Oyola (ILRI), Rosemary Sang (KEMRI), Cornelia Silaghi (FLI), Martin Groschup (FLI), Martin Barasa (VSF-G), Ard Nijhof (FUB) and Cristian Raileanu (FLI) at the #BuildUganda Stakeholder Meeting, Kampala, Uganda, 7 June 2019
Development of a Progressive Management Pathway to assist National and Intern...EuFMD
Step-wise approaches are increasingly used for the reduction, elimination and eradication of a range of major livestock and zoonotic diseases including:, Foot and Mouth Disease (FMD), Peste des Petits Ruminants (PPR)
Rabies, African Animal Trypanosomosis (AAT)
PCPs provide systemic frameworks for planning and evaluating field interventions and enable realistic disease control objectives to be defined and achieved.
AflaNET project: Minimization of aflatoxin contamination in the value chainFrancois Stepman
Wolfgang Buechs (Federal Research Centre for Cultivated Plants - Julius-Kuehn-Institute) AflaNET project: Minimization of aflatoxin contamination in the value chain
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
#2021ReSAKSS - Plenary Session I – presentation by Dr. Eliane Ubalijoro, Executive Director, Sustainability in The Digital Age, Global Hub Director, Canada, Future
Earth, and Co-editor of the 2021 Annual Trends and Outlook Report (ATOR)
FANRPAN Policy Brief: Stemming Aflatoxin in the Groundnut Chain in Sub-Sahara...Francois Stepman
This policy brief has been specifically
prepared to highlight the importance of aflatoxins on human health and trade in Sub-Saharan Africa (SSA). It
contextualizes, (i) the preharvest and post-harvest factors that influence the proliferation of molds and aflatoxin
contamination in groundnuts in the SSA region, (ii) discusses feasible prevention and management strategies and
(iii) presents recommendations .
Planting the orchard – an ILRI livestock vaccine initiative (ILVAC)ILRI
The goal of ILRI’s Vaccine Biosciences group is to build a hub of research excellence dedicated to developing vaccine-based solutions to reduce disease burdens that limit livestock productivity in smallholder and pastoral farming systems.
Strengths of the CGIAR Antimicrobial Resistance HubILRI
Presentation by Arshnee Moodley at the International Vaccine Institute Africa Regional Antimicrobial Resistance Data Sharing and Analysis Virtual Workshop, 29 June 2021
A business approach to poverty reduction: CSA and index insurance - H. Great...CIMMYT
Presented in March 2015 at an international meetings in Montpellier, France, under the auspices of the CGIAR Research Program on Climate Change and Food Securtiy (CCAFS)
Workshop on MLN Diagnostics and Managment in AfricaCIMMYT
Current Phytosanitary Policies to Control the incidence and spread of MLN in Nigeria and Africa, presented at the International Conference on “MLN Diagnostics and Management in Africa,” organized by AGRA (Alliance for Green Revolution in Africa) and CIMMYT, 12-14 May, 2015
Presentation by Kebede Amenu, Coen van Wagenberg, Claudia Ganser, James Noah Ssemanda, Arie Havelaar, Kristine Roesel, Biruk Alemu Gemeda, Lina Mego, Donya Madjdian, Theo Knight-Jones at a stakeholder update workshop on Ethiopia food safety research projects, Addis Ababa, Ethiopia, 20 May 2021.
Boosting Uganda’s Investments in Livestock Development (2019-2023): Introduci...ILRI
Presented by Dan Tumusiime (MAAIF), Bernard Bett (ILRI), Emily Ouma (ILRI), Samuel Oyola (ILRI), Rosemary Sang (KEMRI), Cornelia Silaghi (FLI), Martin Groschup (FLI), Martin Barasa (VSF-G), Ard Nijhof (FUB) and Cristian Raileanu (FLI) at the #BuildUganda Stakeholder Meeting, Kampala, Uganda, 7 June 2019
Development of a Progressive Management Pathway to assist National and Intern...EuFMD
Step-wise approaches are increasingly used for the reduction, elimination and eradication of a range of major livestock and zoonotic diseases including:, Foot and Mouth Disease (FMD), Peste des Petits Ruminants (PPR)
Rabies, African Animal Trypanosomosis (AAT)
PCPs provide systemic frameworks for planning and evaluating field interventions and enable realistic disease control objectives to be defined and achieved.
AflaNET project: Minimization of aflatoxin contamination in the value chainFrancois Stepman
Wolfgang Buechs (Federal Research Centre for Cultivated Plants - Julius-Kuehn-Institute) AflaNET project: Minimization of aflatoxin contamination in the value chain
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
#2021ReSAKSS - Plenary Session I – presentation by Dr. Eliane Ubalijoro, Executive Director, Sustainability in The Digital Age, Global Hub Director, Canada, Future
Earth, and Co-editor of the 2021 Annual Trends and Outlook Report (ATOR)
FANRPAN Policy Brief: Stemming Aflatoxin in the Groundnut Chain in Sub-Sahara...Francois Stepman
This policy brief has been specifically
prepared to highlight the importance of aflatoxins on human health and trade in Sub-Saharan Africa (SSA). It
contextualizes, (i) the preharvest and post-harvest factors that influence the proliferation of molds and aflatoxin
contamination in groundnuts in the SSA region, (ii) discusses feasible prevention and management strategies and
(iii) presents recommendations .
Planting the orchard – an ILRI livestock vaccine initiative (ILVAC)ILRI
The goal of ILRI’s Vaccine Biosciences group is to build a hub of research excellence dedicated to developing vaccine-based solutions to reduce disease burdens that limit livestock productivity in smallholder and pastoral farming systems.
Strengths of the CGIAR Antimicrobial Resistance HubILRI
Presentation by Arshnee Moodley at the International Vaccine Institute Africa Regional Antimicrobial Resistance Data Sharing and Analysis Virtual Workshop, 29 June 2021
A business approach to poverty reduction: CSA and index insurance - H. Great...CIMMYT
Presented in March 2015 at an international meetings in Montpellier, France, under the auspices of the CGIAR Research Program on Climate Change and Food Securtiy (CCAFS)
Index crop insurance and climate-smart agriculture - J. HellinCIMMYT
Presented in March 2015 at the Global Forum for Innovations in Agriculture, Abu Dhabi, under the auspices of the CGIAR Research Program on Agriculture and Food Security (CCAFS)
Role of vectors and their host plants in the epidemiology of maize lethal nec...CIMMYT
Role of vectors and their host plants in the epidemiology of MLN, presented at the International Conference on “MLN Diagnostics and Management in Africa,” organized by AGRA (Alliance for Green Revolution in Africa) and CIMMYT, 12-14 May, 2015
Incidence and Impacts of Maize Lethal Necrosis Disease in EthiopiaCIMMYT
Incidence and impacts of MLN in Ethiopia, presented at the International Conference on “MLN Diagnostics and Management in Africa,” organized by AGRA (Alliance for Green Revolution in Africa) and CIMMYT, 12-14 May, 2015
De groote etal 2010 extension of qpm_aaae v4_slideshareHugo De Groote
Abstract
Biofortified crops can be promoted with extension strategies based on their agronomic qualities, nutritional qualities, or both, but the effectiveness of these different strategies has so far not been studied. Since 2003, quality protein maize (QPM) has been disseminated using both approaches in East Africa. This study therefore analyzes the effectiveness of promoting biofortified crops based on their agronomic and their nutritional qualities on the adoption of QPM cultivars in East Africa. A random sample survey was conducted in Ethiopia, Kenya, Tanzania, and Uganda, with 423 households from QPM extension areas and 539 households from similar areas outside the extension zone. Propensity score matching and regression analysis were used to assess determinants of QPM adoption, including farmers’ awareness of QPM, understanding of its nutritional benefits, and evaluation of agronomic performance to evaluate the agronomic and nutritional extension strategies. Results showed high familiarity with QPM, but low understanding of nutritional benefits. Farmers evaluated QPM varieties as equal or superior to conventional maize for post-harvest traits, but not always for agronomic traits (in particular yield in Ethiopia and Tanzania). Adoption in extension areas varied from 73% in Uganda and 25% in Tanzania to none in Kenya. Key factors that increased adoption were farmers’ participation in extension, having heard of QPM, higher overall evaluation ratings of QPM vs. conventional maize varieties, and understanding of QPM’s nutritional benefits. Agronomic performance was found to be more important than an understanding of nutritional benefits. For biofortified crops to be adopted and have a nutritional impact on target populations, they should, first and foremost, be agronomically equal or superior to conventional varieties. If farmers are convinced of the agronomic performance of biofortified crops, additional gains in adoption can be achieved by focusing extension efforts on imparting farmers with knowledge of the benefits of biofortified crops for human nutrition.
Presented by Irmgard Hoeschle-Zeledon, IITA, at the PCT/SAG (Program Coordination Team/Science Advisory Group) Meeting, Arusha, Tanzania, 22-23 June 2017
Transforming Maize-legume Value Chains –A Business Case for Climate-Smart Ag...CIMMYT
CIMMYT Senior Cropping Systems Agronomist Christian Thierfelder presented on climate-smart agriculture in southern Africa in a webinar titled Climate Resilient Agriculture Success Stories – Making a Case for Scale Up.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
3. Introduction
• Government of Uganda prioritized Maize in the
Development Strategy and Investment Plan (DSIP)
2010/11-2014/15– currently producing 4.2million MT
(2014) with a target of 7.5 million MT by 2017.
• MLN was first reported in 2012 and since then has posed
a significant challenge to the crop.
• Uganda benefited from the FAO sub-regional technical
cooperation project, TCP/SFE/3405,”Regional response
for management and control of Maize Lethal Necrosis
Disease in Eastern Africa.”
• Uganda was allocated/received USD 103,000 to undertake
activities in line with the expected project outputs.
4. MLN National Task Force
Name Title Institution
Stephen Byantwale Ag. Commissioner, Department
of Crop Protection/Chair
MAAIF
Robert Karyeija Commissioner MAAIF
Godfrey Asea Principal Research Officer/
Director
NaCRRI
GeoffreyTusiime Senior Lecturer Makerere University
Charles Lwanga Kasozi Research Officer NaCRRI
Beatrice Namaloba Senior Agric Officer MAAIF
Nelson Masereka Executive Director Uganda Seed
Traders Association
Rodeyn Nicolai Manager NASECO seeds Co.
David Kutunga Senior Agric Inspector,
Epidemics
MAAIF
5. Output 1: Institutional Coordination
• National MLN task forces established and
functional
o Project Coordination: Department of Crop Protection,
MAAIF and NARO
o MLN Technical Taskforce constituted
o Two National Stakeholder Workshops held
o Participated in regional plant pests and disease
platform meetings in Kigali and Nairobi
• A National strategy on management and control of
MLN in Uganda (2015-2020) was developed
6. Output 2.0: Status of MLN spread and capacity
for monitoring occurrence
• Rapid surveillance missions conducted to
determine the extent of spread of the disease
and/or establish the severity of the disease.
• Disseminated rapid surveillance data to
relevant stakeholders.
• Conducted Training of extension staff (100) on
MLN
7. Output 2.0: Status of MLN spread and capacity
for monitoring occurrence
16 districts surveyed in 2
seasons
• Field disease incidence
variable among districts
• Field Incidence of MLN
was highest 2014A
(31.7%) than in first
season 2015 A(31.0%)
and second season
2014B(15.8%).
9. Capacity for MLN diagnosis and detection strengthened
• 604 samples (Sorghum and Napier grass) collected
• DAS-ELISA, lateral flow assays (LFA) kits procured
• Samples assayed independently for MCMV and SCMV
• Highest incidence of MCMV in 2014B
• 100 extension and seed company staff trained
10. Output 3: Knowledge and skills to mitigate MLN
enhanced
.
• 10 radio talk shows and 2 TV shows were
conducted in 2014/2015 in affected and non-
affected areas
• Promotion of appropriate crop production and
management practices (Next Slides)
11. Training and demonstration of best-bet practices
• On- farm testing and
fields of best-bet
varieties- CKH100773
and Bazooka in
Tororo, Busia,
Bulambuli, Bugiri
• Demonstration of MLN
management practices
in Manafwa, Tororo
and Busia
• 6 Field days in eastern
Uganda
12. Entry Name Yield Ears/ Husk Grain Grain Plant MLN(%)
t/ha Rank Plant Cover Text Moist Aspect
1 CKH10773 3.9 1 0.95 5.1 1.5 15.8 2.8 2.68
2 Longe6H 3.6 2 1.03 5.5 1.5 15.0 2.8 6.25
3 Longe9H 3.2 4 1.08 8.8 1.8 15.0 3.0 4.42
4 Longe10H 3.3 3 1.06 5.4 2.0 15.7 3.0 4.84
Mean 3.49 3 1.03 6.2 1.7 15.4 2.9 4.55
LSD
(0.05)
0.79 1 0.15 3.8 0.6 1.3 0.7
CV 7.12 4.71 19.2 10.5 2.6 7.1 46.7
p ns ns ns ns ns ns *
Min 3.19 1 0.95 5.1 1.5 15.0 2.8 2.68
Max 3.85 4 1.08 8.8 2.0 15.8 3.0 6.25
Performances and demonstration of CKH10773 in 2 farmer managed sites in
MLN areas in 2014B
13. Developed and distributed information and training materials (1000
copies each of brochures, leaflets and 150 Training Manuals)
14. Challenges
• Delayed implementation of the project
• Insufficient information on seed transmission at the
beginning of the project
• Continuous maize cropping – different stages
• ineffective control of movement of seed and grain
from affected areas
• Inadequate resources for effective and routine
surveillance and monitoring
• Inadequate control of seed moving across borders
• Weak extension system
15. Lessons learnt
• Involvement of multidisciplinary stakeholders along the
value chain is key to management MLN
• Seed contributes significantly to spread of MLN
• Training and awareness about field diagnosis and
control has helped to limit the disease spread
• Experience from disease epidemics such as BBW,
CBSD and MLN national task forces have guided
Ministry to now put in place a National Plant Protection
and Health Technical Committee as provided for in Plant
Protection and Health Act, 2015