The CGIAR Antimicrobial Resistance Hub has the following strengths: 1) It is supported by 15 CGIAR research centers with local presences in 108 countries and over 50 years of agricultural research experience and partnerships. 2) The International Livestock Research Institute (ILRI) is one of the research centers supporting the hub, with the goal of improving lives through livestock research. 3) The hub aims to mitigate risks of antimicrobial resistance associated with agricultural sectors through surveillance, reducing antimicrobial use, improving biosecurity, and building capacity.

1. Strengths of the CGIAR Antimicrobial Resistance Hub
Arshnee Moodley
International Vaccine Institute Africa Regional Antimicrobial Resistance Data Sharing and Analysis Virtual Workshop
29 June 2021

2. Before 1993
Foundations of good healthcare system
Importance of prudent use and IPC
Strong databases: CRP number, Strain database, Digital and linked
Future
Continue to be bold
Danish consumers are world champions at
organic consumption

3. CGIAR: 15 research centres
Local presence in 108 countries and 50 years of experience
Unequalled partnerships network of more than
3,000 partners from national governments,
academic institutions, global policy bodies,
private companies and NGOs
https://www.cgiar.org/cgiar-at-50/

4. ILRI: Better lives through livestock
Reduce
poverty
Improve
food and
nutrition
security
Improve
natural
resources
Mitigating climate
change, enhancing
resilience and increasing
livestock productivity
Sustainable Livestock
Systems
Delivering solutions for
livestock, zoonotic and
foodborne diseases
Animal and Human
Health
Efficient livestock
production driving
inclusive growth and
employment
Policies, Institutions &
Livelihoods
Improving genetics for
better productivity and
profitability
Livestock Genetics
Better nutrition for
improved animal
productivity
Feed and Forage
Development
Taking livestock
solutions to scale for
inclusive development
Impact at Scale

5. Main campuses: Nairobi, Kenya and Addis Ababa, Ethiopia
Offices in 15 other countries
• Staff: 700
• Budget: US$100 million (2021)
• Senior scientists from 40 countries
ILRI’s presence (since the early 1970s)

6. ILRI: Better lives through livestock!
Source: Options for the Livestock Sector in Developing and Emerging Economies to 2030 and Beyond. World Economic Forum White Paper January 2019
Market value of Africa’s animal-source foods to grow to ∼$151
billion by 2050 (from ∼$37bn in 2019)
Most livestock products are sold locally and informally
FAO, 2019
Global and national food trade policies to mitigate AMR:
- bans
- user fees (e.g. increase price of antimicrobial)
- restrictions on products raised using antimicrobials
(Avraam et al 2021)

7. Food security
Livelihoods
Incentives
Intensification (inc. productivity)
Reducing Antimicrobial use
Deficiencies
Global interests
National interests
Addressing AMR is a balancing act in LMICs
Access Excess
Impact on livestock output:
decline in global livestock
production 2.6-7.5% per year
Impact on global poverty:
pronounced increase in extreme
poverty- additional 28.3 million
people (high-impact AMR scenario)

8. Understanding impacts of AMR in the local context
Making a case for country investment
LMICs
How much human AMR comes from agriculture? Don’t Know
Interventions shown to reduce use at scale No
Interventions are affordable Don’t know
Interventions are feasible Maybe, maybe not
Unintended negative consequences Maybe large
Effect on human and animal overall well-beings Don’t know

9. CGIAR AMR Hub mitigating agricultural associated AMR risks
www.amr.cgiar.org

10. Fundamentals of reducing AMU and spread of AMR in
the agricultural sector
Reduce use
• AMU surveillance
• Ban/restrictions
• Education-Awareness
compaigns
• Evidence based treatment
decisions (diagnostics)
• Treatment guidelines
• Vaccines use
• Limiting profit of prescribers
• Differential taxation
Reduce transmission
• AMR surveillance
• Biosecurity
• Hygiene/decontamination

11. Fundamentals of reducing AMU and spread of AMR in the
agricultural sector
Reduce use
• AMU surveillance
• Ban/restriction of specific
antimicrobials
• Education-Awareness compaigns
• Evidence based treatment decisions
• Treatment guidelines
• Vaccines use
• Limiting profit of prescribers
Reduce transmission
• AMR surveillance
• Biosecurity
• Hygiene/decontamination
Challenges in LMICs
No
financial
subsidies
Poor
quality
inputs e.g
feed
Poor
vaccine
uptake
Corruption
Low trust
in
authority

12. Hub project activities
Major activities
• AMU, drivers, KAP
• AMR Prevalence & Transmission (interfaces)
• Cap. Building (lab cap and mentorship)
• Interventions incl. pilot studies, economic analyses
Minor projects
• AMU and AMR in crop systems
• Fate and transport of AMR in water bodies
• AMR in wildlife and bushmeat
• AMR and manure
• AMR Policy
ILRI alone: 2020-2025, AMR
projects equal US$ 6.8 million

13. Policy challenges in LMICs
• Low political commitment
• Little awareness of the issue
• Weak engagement of all
stakeholders
• Limited capacity and resources to
implement policies
• Absence of national surveillance
• Data for action??
• Kenya: $2.64M ($ 0.3M animal sector)
• Uganda: $11.28M (3.7M animal sector
• Denmark: $149M ($36M-animal sector)

14. CGIAR AMR Hub
• Strength – partnerships (Multi CGIAR centres, external partners incl. governments

15. Mitigating agricultural associated AMR risks together!

16. THANK YOU