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1
CARDIOPULMONARY
RESUSCITATION
Chair of Anesthesiology and Intensive Care
Yerevan State Medical University
G. G. Mkhoyan
2
HISTORICAL REVIEW
 5000 - first artificial mouth to mouth
3000 BC ventilation
 1780 – first attempt of newborn
resuscitation by blowing
 1874 – first experimental direct cardiac
massage
 1901 – first successful direct cardiac massage
in man
 1946 – first experimental indirect cardiac
massage and defibrillation
 1960 – indirect cardiac massage
 1980 – development of cardiopulmonary
resuscitation due to the works of Peter
Safar
3
Causes of cardiac
arrest
cardiac
extracardiac
Primary lesion of cardiac muscle leading to the
progressive decline of contractility, conductivity
disorders, mechanical factors
all cases accompanied
with hypoxia
4
Causes of circulation arrest
Cardiac
• Ischemic heart disease
(myocardial infarction,
stenocardia)
• Arrhythmias of different
origin and character
• Electrolytic disorders
• Valvular disease
• Cardiac tamponade
• Pulmonary artery
thromboembolism
• Ruptured aneurysm of
aorta
Extracardiac
• airway obstruction
• acute respiratory failure
• shock
• reflector cardiac arrest
• embolisms of different
origin
• drug overdose
• electrocution
• poisoning
5
Diagnosis of cardiac arrest
Symptoms of cardiac arrest
 absence of pulse on carotid arteries – a
pathognomonic symptom
 respiration arrest – may be in 30 seconds after
cardiac arrest
 enlargement of pupils – may be in 90 seconds after
cardiac arrest
Blood pressure measurement

Taking the pulse on peripheral
arteries

Auscultation of cardiac tones
Loss of time !!!
6
Sequence of operations
 Check responsiveness
 Call for help
 Correctly place the victim and ensure
the open airway
 Check the presence of spontaneous
respiration
 Check pulse
 Start external cardiac massage and
artificial ventilation
7
In case of unconsciousness it
is necessary to estimate
quickly
 the open airway
 respiration
 hemodynamics
8
Main stages of resuscitation
A (Airway) – ensure open airway by preventing
the falling back of tongue, tracheal
intubation if possible
B (Breathing) – start artificial ventilation of
lungs
C (Circulation) – restore the circulation by
external cardiac massage
D (Differentiation, Drugs, Defibrilation) –
quickly perform differential diagnosis of
cardiac arrest, use different medication and
electric defibrillation in case of ventricular
fibrillation
9
A (Airway)
ensure open
airway
10
Open the airway using a head
tilt lifting of chin. Do not tilt the
head too far back
Check the pulse on
carotid artery using
fingers of the other hand
11
B (Breathing)
Tilt the head back
and listen for. If
not breathing
normally, pinch
nose and cover
the mouth with
yours and blow
until you see the
chest rise.
12
mouth to mouth or mouth
to nose respiration
ventilation by a face mask and a
self-inflating bag with oxygen
2 initial subsequent breaths
wait for the end of expiration
10-12 breaths per minute with a volume of app.
800 ml, each breath should take 1,5-2 seconds
Control over the ventilation
check chest movements during ventilation
check the air return
Algorithm
for artificial ventilation
13
C. Circulation
Restore the circulation, that is
start external cardiac massage
14
2 mechanisms explaining the
restoration of circulation by
external cardiac massage
Cardiac
pump
Thoracic
pump
15
Cardiac pump during the cardiac
massage
Blood pumping is
assured by the
compression of heart
between sternum and
spine
Between
compressions
thoracic cage is
expanding and heart
is filled with blood
16
Thoracic pump at the cardiac massage
Blood circulation is
restored due to the change
in intra thoracic pressure
and jugular and subclavian
vein valves
During the chest
compression blood is
directed from the
pulmonary circulation to
the systemic circulation.
Cardiac valves function as
in normal cardiac cycle.
17
ALGORITHM of Cardiopulmonary resuscitation
4 cycles: 15 compression
and 2 breaths
10 cycles: 5 compression
and 1 breath
check the pulse on carotid arteries (5 sec)
in case of absence of pulse continue resuscitation
2 breaths (duration 1 – 1.5 sec.)
palpation of pulse on carotid arteries (5 – 10 sec.)
in case of absence of pulse initiate
external cardiac massage
1
person
compression rate 80 – 100/min.
compression/breath = 15 : 2
compression rate 80 – 100/min
compression/breath = 5 : 1
2 breaths in 4 – 7 sec. breath during 1 – 1.5 sec. after
each 5th compression
2
persons
a
a
a
18
VENTRICULAR FIBRILLATION OR PULSELESS TACHYCARDIA
Witnessed Unwitnessed
Precordial thump
Check pulse, if none:
Begin CPR
Defibrillate with 200 joules
Defibrillate with 200-300 joules
Establish IV access, intubate
Adrenaline 1 mg push
Defibrillate with 360 joules
Lidocaine 1 mg/kg IV, ET
Defibrillate with 360 joules
19
Possible arrhythmias after
cardiac defibrillation
ventricular tachycardia
bradyarrythmia including
electromechanical dissociation and
asystole
supraventricular arrhythmia
accompanied with tachycardia
supraventricular arrhythmia with
normal blood pressure and pulse
rate
20
Operations in case of asystole
Asystole
• Start CPR
• IV line
• Adrenaline:IV 1 mg, each 3-5 min.
-or
- intratracheal 2 - 2.5 mg
- in the absence of effect increase
the dose
-Atropine 1 mg push (repeated once
in 5 min)
•Na Bicarbonate 1 Eq/kg IV
•Consider pacing
21
Drugs used in CPR
• Atropine – can be injected bolus, max 3 mg to
block vagal tone, which plays significant role in
some cases of cardiac arrest
• Adrenaline – large doses have been
withdrawn from the algorithm. The
recommended dose is 1 mg in each 3-5 min.
• Vasopresine – in some cases 40 U can
replace adrenaline
• Amiodarone - should be included in algorithm
• Lidocaine – should be used only in ventricular
fibrillation

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  • 1. 1 CARDIOPULMONARY RESUSCITATION Chair of Anesthesiology and Intensive Care Yerevan State Medical University G. G. Mkhoyan
  • 2. 2 HISTORICAL REVIEW  5000 - first artificial mouth to mouth 3000 BC ventilation  1780 – first attempt of newborn resuscitation by blowing  1874 – first experimental direct cardiac massage  1901 – first successful direct cardiac massage in man  1946 – first experimental indirect cardiac massage and defibrillation  1960 – indirect cardiac massage  1980 – development of cardiopulmonary resuscitation due to the works of Peter Safar
  • 3. 3 Causes of cardiac arrest cardiac extracardiac Primary lesion of cardiac muscle leading to the progressive decline of contractility, conductivity disorders, mechanical factors all cases accompanied with hypoxia
  • 4. 4 Causes of circulation arrest Cardiac • Ischemic heart disease (myocardial infarction, stenocardia) • Arrhythmias of different origin and character • Electrolytic disorders • Valvular disease • Cardiac tamponade • Pulmonary artery thromboembolism • Ruptured aneurysm of aorta Extracardiac • airway obstruction • acute respiratory failure • shock • reflector cardiac arrest • embolisms of different origin • drug overdose • electrocution • poisoning
  • 5. 5 Diagnosis of cardiac arrest Symptoms of cardiac arrest  absence of pulse on carotid arteries – a pathognomonic symptom  respiration arrest – may be in 30 seconds after cardiac arrest  enlargement of pupils – may be in 90 seconds after cardiac arrest Blood pressure measurement  Taking the pulse on peripheral arteries  Auscultation of cardiac tones Loss of time !!!
  • 6. 6 Sequence of operations  Check responsiveness  Call for help  Correctly place the victim and ensure the open airway  Check the presence of spontaneous respiration  Check pulse  Start external cardiac massage and artificial ventilation
  • 7. 7 In case of unconsciousness it is necessary to estimate quickly  the open airway  respiration  hemodynamics
  • 8. 8 Main stages of resuscitation A (Airway) – ensure open airway by preventing the falling back of tongue, tracheal intubation if possible B (Breathing) – start artificial ventilation of lungs C (Circulation) – restore the circulation by external cardiac massage D (Differentiation, Drugs, Defibrilation) – quickly perform differential diagnosis of cardiac arrest, use different medication and electric defibrillation in case of ventricular fibrillation
  • 10. 10 Open the airway using a head tilt lifting of chin. Do not tilt the head too far back Check the pulse on carotid artery using fingers of the other hand
  • 11. 11 B (Breathing) Tilt the head back and listen for. If not breathing normally, pinch nose and cover the mouth with yours and blow until you see the chest rise.
  • 12. 12 mouth to mouth or mouth to nose respiration ventilation by a face mask and a self-inflating bag with oxygen 2 initial subsequent breaths wait for the end of expiration 10-12 breaths per minute with a volume of app. 800 ml, each breath should take 1,5-2 seconds Control over the ventilation check chest movements during ventilation check the air return Algorithm for artificial ventilation
  • 13. 13 C. Circulation Restore the circulation, that is start external cardiac massage
  • 14. 14 2 mechanisms explaining the restoration of circulation by external cardiac massage Cardiac pump Thoracic pump
  • 15. 15 Cardiac pump during the cardiac massage Blood pumping is assured by the compression of heart between sternum and spine Between compressions thoracic cage is expanding and heart is filled with blood
  • 16. 16 Thoracic pump at the cardiac massage Blood circulation is restored due to the change in intra thoracic pressure and jugular and subclavian vein valves During the chest compression blood is directed from the pulmonary circulation to the systemic circulation. Cardiac valves function as in normal cardiac cycle.
  • 17. 17 ALGORITHM of Cardiopulmonary resuscitation 4 cycles: 15 compression and 2 breaths 10 cycles: 5 compression and 1 breath check the pulse on carotid arteries (5 sec) in case of absence of pulse continue resuscitation 2 breaths (duration 1 – 1.5 sec.) palpation of pulse on carotid arteries (5 – 10 sec.) in case of absence of pulse initiate external cardiac massage 1 person compression rate 80 – 100/min. compression/breath = 15 : 2 compression rate 80 – 100/min compression/breath = 5 : 1 2 breaths in 4 – 7 sec. breath during 1 – 1.5 sec. after each 5th compression 2 persons a a a
  • 18. 18 VENTRICULAR FIBRILLATION OR PULSELESS TACHYCARDIA Witnessed Unwitnessed Precordial thump Check pulse, if none: Begin CPR Defibrillate with 200 joules Defibrillate with 200-300 joules Establish IV access, intubate Adrenaline 1 mg push Defibrillate with 360 joules Lidocaine 1 mg/kg IV, ET Defibrillate with 360 joules
  • 19. 19 Possible arrhythmias after cardiac defibrillation ventricular tachycardia bradyarrythmia including electromechanical dissociation and asystole supraventricular arrhythmia accompanied with tachycardia supraventricular arrhythmia with normal blood pressure and pulse rate
  • 20. 20 Operations in case of asystole Asystole • Start CPR • IV line • Adrenaline:IV 1 mg, each 3-5 min. -or - intratracheal 2 - 2.5 mg - in the absence of effect increase the dose -Atropine 1 mg push (repeated once in 5 min) •Na Bicarbonate 1 Eq/kg IV •Consider pacing
  • 21. 21 Drugs used in CPR • Atropine – can be injected bolus, max 3 mg to block vagal tone, which plays significant role in some cases of cardiac arrest • Adrenaline – large doses have been withdrawn from the algorithm. The recommended dose is 1 mg in each 3-5 min. • Vasopresine – in some cases 40 U can replace adrenaline • Amiodarone - should be included in algorithm • Lidocaine – should be used only in ventricular fibrillation