The document discusses several famous Renaissance artists and their most notable works. Leonardo da Vinci is discussed, notably his masterpiece the Mona Lisa. Michelangelo is mentioned, known for his frescoes on the ceiling of the Sistine Chapel. Raphael is covered, recognized for paintings like the Sistine Madonna. Titian's most famous painting is The Assumption of the Virgin. Botticelli's Primavera, based on mythology, is highlighted as his most renowned work.