The Renaissance period between the 14th and 16th centuries was a cultural movement known as the "Rebirth" that began in Italy. Artists during this time focused on realistic human anatomy, use of perspective, and integrating Christian traditions into their highly skilled works. Some of the greatest Renaissance artists included Leonardo Da Vinci, Michelangelo, Raphael, and Donatello, who created famous pieces like the Mona Lisa, Sistine Chapel, School of Athens, and Saint Mark during the peak of the High Renaissance between 1490-1530 in cities like Florence, Rome, and Venice.