2D PLANNING IN BRAIN TUMOR
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This document outlines the steps for 2D planning in brain tumor treatment. It describes using a clinical simulator and digitizer to outline the tumor on sequential CT slices using landmarks from a localization image. Points are marked on each slice and connected to generate the tumor contour. Margins are added to create the treatment field. Examples are given of different beam arrangements like parallel opposed pairs and wedge combinations. Quality assurance procedures like checking port films are also discussed. Examples of plans for conditions like pituitary tumors and whole brain radiotherapy are included. The importance of sparing organs at risk is emphasized.
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fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
Broadbent published papers in 1937 describing craniofacial measurements in children, establishing him as the father of radiographic cephalometry. Cephalometry helps with diagnosis, classification of skeletal and dental abnormalities, treatment planning, evaluating treatment results, and predicting growth. Conventional cephalometry has disadvantages like external error and lack of defined outlines. Photocephalometry introduced in 1970s allows measurement of soft tissues. Digital cephalometry provides advantages like dose reduction and 3D reconstruction. 3D modeling and stereolithography are now used for surgical planning and simulation.
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
Broadbent published papers in 1937 describing craniofacial measurements in children, establishing him as the father of radiographic cephalometry. Cephalometry helps with diagnosis, classification of skeletal and dental abnormalities, treatment planning, evaluating treatment results, and predicting growth. Conventional cephalometry has disadvantages like external error and lack of defined outlines. Photocephalometry introduced in 1970s allows measurement of soft tissues. Digital cephalometry provides advantages like dose reduction and 3D reconstruction. 3D modeling is now used for surgical planning and simulation, with stereolithography producing anatomical models.
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
Broadbent published papers in 1937 describing craniofacial measurements in children, establishing him as the father of radiographic cephalometry. Cephalometry helps with diagnosis, classification of skeletal and dental abnormalities, treatment planning, evaluating treatment results, and predicting growth. Conventional cephalometry has disadvantages like external error and lack of defined outlines. Photocephalometry introduced in 1970s allows quantitative soft tissue analysis. Digital cephalometry provides advantages like dose reduction and 3D reconstruction. 3D modeling is now used for surgical planning and simulation as well as splint and implant fabrication.
Cancer Still Waiting: Impact of COVID-19 Crisis on Cancer Patients and their ...
Cancer Still Waiting: Impact of COVID-19 Crisis on Cancer Patients and their ...Canadian Cancer Survivor Network
Don't miss our upcoming webinars! Subscribe today!
In this webinar:
In May-June, 2020, the Canadian Cancer Survivor Network (CCSN) commissioned Leger to conduct a national survey to evaluate the impact that COVID-19 has had on cancer patients, survivors, pre-diagnosis patients, and caregivers. The results of our first survey revealed that the pandemic response has triggered another public health crisis - the postponement and cancellation of essential cancer tests, procedures, and treatments.
CCSN commissioned Leger for a second survey in December, 2020 to evaluate the impact that the suspension of cancer services during the first wave is currently having on those who have been affected by cancer.
Join CCSN and Leger as we present the results of the COVID-19 and Cancer Care Disruption in Canada Survey - Wave 2 and hear from members of the cancer community about how the pandemic has directly impacted them.
View the YouTube video: https://youtu.be/qN4Hq7OtBys
Follow CCSN on social media:
Twitter - https://twitter.com/survivornetca
Facebook - https://www.facebook.com/CanadianSurvivorNet
Instagram: https://www.instagram.com/survivornet_ca/
Pinterest - https://www.pinterest.com/survivornetworkRAPIDO TRIAL RECTUM
The RAPIDO trial tested a new experimental treatment for locally advanced rectal cancer that involved short-course radiotherapy followed by chemotherapy before surgery, compared to the standard treatment of long-course chemoradiotherapy followed by surgery and then chemotherapy. The results showed that the experimental treatment led to a lower rate of disease-related treatment failures and distant metastases, along with a doubled rate of pathologic complete responses, without increasing toxicities or compromising survival rates. This provides evidence that the experimental approach may be a new standard of care for high-risk locally advanced rectal cancer.
KCR Case Study: Pediatric Pain Management
The KCR rescue team successfully salvaged an analgesic compound study in pediatric pain management that was facing recruitment problems and delays. They developed a comprehensive strategy that included feasibility assessment, careful site selection targeting specific surgery types, addressing regulatory and operational challenges, and providing project management and clinical support. As a result, the target enrollment of 13 adults and 40 adolescents was achieved within 32 weeks, the sponsor expressed confidence in KCR, and a new study in younger pediatric patients was awarded.
OBESITY
The document discusses obesity and cancer in India. It notes that India accounts for 15% of the world's obese population with 30 million obese people. Obesity is estimated to cause 3-4 million deaths worldwide annually. The document then focuses on lung cancer, the leading cause of cancer deaths in India. It discusses the causes of lung cancer as smoking and air pollution, and notes that 90% of lung cancers are caused by tobacco smoke. The stages, symptoms, diagnosis, and treatment options for lung cancer are summarized. The treatment section focuses on surgery, radiation therapy, chemotherapy, and targeted therapies as options.
Webinar: Oncology Trial Recruitment: Challenging Indications and Challenging ...
Medpace experts discuss how to overcome oncology recruitment challenges for clinical trials for specific populations, indications, and challenging studies.
Cephalometric analysis natarajan
Cephalometric analysis has evolved from traditional 2D radiographs to 3D digital techniques. Broadbent is considered the father of radiographic cephalometry for developing the technique in 1937. While conventional cephalometry is useful for diagnosis, treatment planning and evaluation, it has disadvantages like errors and manual processing. Photocephalometry introduced in 1970s allowed measuring soft tissue changes but was complex. Digital cephalometry since 1980s has advantages like dose reduction and storage. 3D modeling using CT, stereophotogrammetry and laser scans now allows accurate anatomical models for pre-operative simulation and custom implants. Stereolithography is used to produce 3D printed models but has limitations of cost and radiation dose. 3D navigation during
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Ductal carcinoma in situ (DCIS) can be treated with surgery, or with Active Monitoring for low-risk DCIS. Chemotherapy is not needed, although sometimes radiation or hormone therapy are suggested. Most DCIS never develops into an invasive cancer. In part 2 of the DCIS webinar series, we discuss where research is taking us. For those who have already received treatment and surgery, this will be essential information to learn and share with family and friends so they know their level of risk too. You can also share this information with your medical team to help them keep up with the latest DCIS research and care.
Our panelists, Dr. Shelley Hwang and Deborah Collyar, discuss ways to de-escalate the fear of recurrence and ways to ensure decisions are made without fear.
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This document provides an overview of the approach to prostate SBRT planning. It discusses the evidence supporting SBRT, patient selection, immobilization techniques, imaging protocols, target delineation guidelines, dose selection, planning constraints, quality assurance procedures, and peri-treatment management. The key advantages of SBRT for prostate cancer are the short treatment time of 5 fractions, high biological effective dose achieved, and comparable oncologic outcomes to other EBRT techniques with side effects that are earlier but also resolve sooner. Careful planning and quality assurance throughout the process are emphasized.
Technology Assessment, Outcomes Research and Economic Analyses
This document discusses technology assessment, outcomes research, and economic analyses in healthcare. It provides background on rising healthcare costs in the US and outlines a hierarchy for assessing new medical technologies from technical efficacy to patient and societal outcomes. Randomized controlled trials are described as the gold standard but limitations are noted. Alternative study designs like modeling and assessing intermediate outcomes are proposed when RCTs are not feasible. The document uses CT for appendicitis as an example to work through initial steps in outcomes research. It also discusses limitations and alternative outcomes like assessing the therapeutic value of diagnostic tests.
Decentralized Monitoring in Clinical Trials
Decentralized monitoring in clinical trials refers to a modern approach to monitoring the progress, safety, and data integrity of clinical trials using remote and technology-driven methods. Traditional clinical trial monitoring involves frequent on-site visits by monitors to ensure that the trial is conducted according to the protocol and regulatory requirements. However, this approach can be resource-intensive, time-consuming, and may not always provide real-time insights.
Decentralized monitoring leverages technology, data analytics, and remote communication tools to monitor various aspects of clinical trials. Here are some key components of decentralized monitoring:
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Report Back from ASCO 2023: What’s the Latest News in Metastatic Breast Cancer?
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fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
fdocuments.in_cephalometric-analysis-natarajan_Akshay.pptx
Cancer Still Waiting: Impact of COVID-19 Crisis on Cancer Patients and their ...
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Part II: DCIS Research: De-escalating the Fear of Recurrence
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June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
une 2024 Oncology Cartoons By Dr Kanhu Charan Patro
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This document appears to be a newsletter or e-book with summaries of oncology research articles and case studies from March 2024 to mid-April 2024. It includes summaries on topics like radiotherapy dosing in head and neck cancer, genetic factors in breast cancer treatment, algorithms for surveillance of colorectal polyps, emerging tracers in neuro-oncology, target delineation workflows for various cancer sites, radiation therapy options for pituitary adenoma, comparisons of APBI guidelines for breast cancer, and associations between Chlamydia psittaci and orbital MALT lymphoma. The document also notes that April is National Oral Cancer Awareness Month.
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TARGET DELINEATION IN ANAL CANAL CANCER BY DR KANHU
1. The document discusses target delineation and radiation therapy workflow for anal cancer, including definitions of gross tumor volume (GTV) and clinical target volumes (CTVs) based on anatomical locations.
2. It provides guidelines for determining margins around the GTV and nearby anatomical structures to create the CTVs for the primary tumor (CTVp), involved nodes (CTVn), and elective nodal regions (CTVnLR) to cover possible microscopic disease.
3. Treatment planning volumes (PTVs) are created by adding margins to the CTVs, with the PTV-HR receiving the full prescription dose and the PTV-LR receiving a lower dose.
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The document outlines the steps and guidelines for target delineation in vulval cancer radiation therapy planning. It discusses delineating the gross tumor volume (GTV), clinical target volume (CTV), organs at risk (OAR), and planning target volume (PTV). Specific guidelines are provided for contouring depending on the location and extent of the primary tumor, including the vulva, mons pubis, vagina, anorectum, urethra, and clitoris. Radiation dose parameters and OAR constraints are also reviewed. The target delineation workflow aims to adequately cover suspected disease while minimizing dose to surrounding healthy tissues.
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This document outlines the 10 step workflow for target delineation in cervical cancer radiotherapy treatment planning. It describes the clinical target volumes that should be contoured for the primary gross tumor (GTVp), primary clinical target (CTVp), nodal gross tumor (GTVn), nodal clinical targets (CTVn) and elective nodal volumes. It provides explanations and guidelines for delineating each target volume, including the parametrium and nodal regions. Diagrams and images are included to illustrate the anatomical locations and boundaries of the target volumes.
Oncology cartoons by Dr Kanhu Charan Patro
This document provides guidance on target volume delineation for vulval cancer from the Royal College of Radiologists. It outlines the clinical target volume (CTV) for different disease sites, including the vulva, mons pubis, vagina, anorectum, urethra and pelvic nodes. Contouring workflows and organ-at-risk constraints are also discussed. Recommendations are given for radiation dose and treatment of resectable and unresectable head and neck cancer. The final item notes that smoking increases the risk of kidney cancer.
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Molecular Profile of Endometrial cancer.
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ONCOLOGY CARTOONS JANUARY 2024 BY DR KANHU CHARAN PATRO
This document discusses cervical cancer awareness month in January and provides 3 recommendations: 1) Be loyal to your partner to reduce risk of HPV infection, 2) Maintain genital hygiene, 3) Get vaccinated against HPV to prevent cervical cancer, and 4) Get screened regularly to detect cervical cancer early.
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This document discusses types of data in statistics. It defines qualitative and quantitative data, and describes different types of quantitative data like discrete, continuous, ordinal, and nominal. Examples of love and fight data are provided to illustrate these concepts. The document concludes with a short poem about not fighting in marriage.
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PORTAL VEIN TUMOR THROMBOSIS SBRT/DR KANHU CHRAN PATRO
1) SBRT is an effective treatment for hepatocellular carcinoma (HCC) patients with portal vein tumor thrombosis (PVTT). In a study of 70 HCC patients with PVTT treated with SBRT, median survival was 10 months and 6-month and 12-month survival rates were 67.3% and 40% respectively.
2) Patients who received SBRT combined with transarterial chemoembolization (TACE) had significantly longer survival compared to those who did not receive TACE after SBRT.
3) SBRT is a promising bridging therapy prior to liver transplantation or hepatectomy by downstaging PVTT to make these curative procedures possible.
DECEMBER 2023 ONCOLOGY CARTOONS DRKANHU CHARAN PATRO
Here are the key points about the hepatitis B vaccine and liver cancer:
- Hepatitis B virus (HBV) infection can lead to chronic hepatitis B and significantly increase the risk of developing liver cancer later in life.
- The hepatitis B vaccine is effective at preventing HBV infection and therefore helps prevent liver cancers caused by the virus. It was the first vaccine referred to as an "anti-cancer" vaccine by the FDA.
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- The hepatitis B vaccine is available and affordable in India, ranging from around 45 rupees per pediatric dose to 250 rupees for the
DEBATE IN CA BLADDER TMT VS CYSTECTOMY
1) Dr. KanhuCharanPatro is a radiation oncologist who specializes in stereotactic radiation oncology for treating cancers like urinary bladder cancer.
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3) A meta-analysis of over 50,000 patients found that TMT had non-inferior overall survival rates to cystectomy at over 10 years and may be a reasonable alternative for patients who cannot undergo or do not want surgery.
ROSE CASE CARDIAC ARRHYTHMIA SBRT
1) Stereotactic arrhythmia radioablation (STAR) is a non-invasive technique using SBRT to treat refractory ventricular tachycardia (VT).
2) The first human case was reported in 2015 where a single fraction of 33Gy targeted to the scar substrate significantly reduced the VT burden.
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- 1. 2 D PLANNING IN BRAIN TUMOR DR KANHU CHARAN PATRO 4/5/2022 1 DR KANHU CHARAN PATRO MD,DNB(RADIATION ONCOLOGY),MBA,FAROI(USA),PDCR,CEPC HOD,RADIATION ONCOLOGY Mahatma Gandhi Cancer Hospital And Research Institute, Visakhapatnam drkcpatro@gmail.com M-9160470564
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- 5. STEPS FOR 2D PLAN • See the scale on TOPO • Find the localizer on TOPO • Follow the slice with localizer on TOPO • Fix one anterior point • Fix the posterior point • Extrapolate scale on a paper • Measure the tumor distance from your fixed point • Mark the points on localizer on each line • Join the line • You will get tumor outline • Give margin • Open the field 4/5/2022 5
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- 48. DO NOT DARE TO SCARE OAR NEEDS EXTRA CARE OTHERWISE RARE WILL NOT BE RARE
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