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MANAGEMENT OF DIFFUSE GLIOMAS
4/30/2022 1
DR KANHU CHARAN PATRO
MD,DNB(RADIATION ONCOLOGY),MBA,FAROI(USA),PDCR,CEPC
HOD,RADIATION ONCOLOGY
Mahatma Gandhi Cancer Hospital And Research Institute, Visakhapatnam
drkcpatro@gmail.com M-9160470564
RADIOLOGY OF CANCER RECTUM
Slow my flow
• Staging
• Normal structures
• Diseased rectum
• Post RT picture
• Treatment algorithm
• Contouring mesorectum
• Contouring guidelines
• References
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4/30/2022 3
Nodal staging
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MRI PROTOCOL
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4/30/2022 6
REPORTING STEPS
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STRUCTURED
MRI
REPORTING
4/30/2022 8
STRUCTURED
MRI
FORMAT
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Structure identification
1 Anal verge
2 Anorectal junction
3 Rectosigmoid junction
4 Parts of rectum
5 Mesorectum
6 Mesorectal fascia
7 Mucosa and sub mucosa
8 Levator ani Muscle complex
9 External sphincter
10 Internal sphincter
11 Intersphincteric space
12 Peritoneal reflection
13 Ischiorectal fossa
14 Mesorectal venous plexus
15 Puborectalis
16 Adjacent structures
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1.IDENTFYING ANAL VERGE
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2.ANORECTAL JUNCTION
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3.RECTOSIGMOID JUNCTION
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4.PARTS OF RECTUM
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5.Mesorectum
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6. MRF- mesorectal fascia
7.Mucosa /Submucosa/MP
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8-LEVATOR ANI
4/30/2022 22
9.10,11
Muscles of rectum-Internal sphincter, Intersphincteric space, External sphincter
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4/30/2022 24
12.PERITONEL REFLECTION- SEA GULL SIGN
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Ischiorectal fossa
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14.Mesorectal venous plexuses
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15.Puborectalis
4/30/2022 30
15.Puborectalis
4/30/2022 31
16.ADJACENT STRUCTURES
4/30/2022 32
SL NO PARAMETER INFERENCE
1 SITE
2 SIZE
3 CIRUMFERNCE INVOLVEMENT
4 CLOCK POSITION
5 TYPE OF GROWTH
6 MUCINOS VS NON-MUCINOUS
7 DISTANCE FROM ANAL VERGE
8 RELATION WITH PERITONEAL REFLECTION
9 PERIRECTAL FAT STRANDING
10 PROXIMAL OBSTRUCTION
11 DEPTH OF EXTRAMURAL INVASION
12 DISTANCE FROM MESOREACTL FASICA
13 CRM STATUS
14 RETRORECTAL AREA INVOLVEMENT
15 INTERNAL SPHICNCTER INVOLVEMENT
4/30/2022 33
SL NO PARAMETER INFERENCE
16 EXTERNAL SPHINCTER INVOLVEMENT
17 INTERSPHINCTERIC SPACE INVOLVEMENT
18 ISCHIORECTAL FOSSA INVOLVEMENT
19 ISCHIOANAL FOSSA INVOLVEMENT
20 ADAJCENT STRACTURE INVOLVEMENT
21 PERIRECTAL SEEDING
22 EXTRAMURAL VASCULAR INVASION
23 EMVI GRADING
24 MESORECTAL NODE
25 LEFT ILIAC NODE
26 RIGHT ILIAC NODE
27 LEFT INGUINAL NODE
28 RIGHT INGUINAL NODE
29 PARAAORTIC NODE
30 FINAL STAGING
4/30/2022 34
1,2-Site /Size
4/30/2022 35
3.Circumference involvement
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4.Clock position
4/30/2022 37
4/30/2022 38
4.Clock position
5.Types of growth
4/30/2022 39
4/30/2022 40
6.MUCINOUS VS NON MUCINOUS
4/30/2022 41
Mucinous vs non mucinous growth
4/30/2022 42
4/30/2022 43
7.Distance from anal verge
4/30/2022 44
Rectum
Rectum
8.RELATION WITH PERITONEAL REFLECTION
4/30/2022 45
9.Desmoplastic reaction vs tumor fat stranding
4/30/2022 46
10.Proximal obstruction
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11.Depth of extramural invasion
4/30/2022 48
12.DISTANCE FROM MESOREACTL FASICA
4/30/2022 49
Threatened
MRF
4/30/2022 51
4/30/2022 52
4/30/2022 53
13.DEFINING CRM STATUS
4/30/2022 54
14.RETRORECTAL SPACE INVOLVEMENT
4/30/2022 55
15/16/17-SPHINCTER COMPLEX INVOLVEMENT
4/30/2022 56
4/30/2022 57
18/19- Ischiorectal fossa involvement
4/30/2022 58
20.ADAJCENT STRACTURE INVOLVEMENT
4/30/2022 59
4/30/2022 60
22.Extramural lympho-vascular invasion
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4/30/2022 62
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23.Extramural lympho-vascular invasion grading
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EMVI-1
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EMVI-2
4/30/2022 69
EMVI-3
4/30/2022 70
EMVI-4
4/30/2022 71
4/30/2022 72
NODAL DRAINAGE IN CANCER RECTUM
4/30/2022 73
24.MESORECTAL NODE
4/30/2022 74
4/30/2022 75
25,26-left ant right iliac node
4/30/2022 76
27,28-Inguinal node
4/30/2022 77
29-Paraaortic node
4/30/2022 78
30.Final Staging
4/30/2022 79
Risk stratification
4/30/2022 80
Decision making
4/30/2022 81
4/30/2022 82
TME and TME VARIANTS
4/30/2022 83
Restaging
4/30/2022 84
RESPONSE ASSESMENT AFTER NEOADJUVANT
TREATMENT IN CANCER RECTUM
4/30/2022 85
4/30/2022 86
4/30/2022 87
4/30/2022 88
Low signal on the ADC map, indicating restricted
diffusion/RESIDUAL
HIGH signal on the DWI, indicating restricted
diffusion/RESIDUAL
4/30/2022 89
4/30/2022 90
• Example of a patient with several irregularly enlarged cN+
nodes at primary staging. After chemoradiotherapy, most nodes
have disappeared and only a small node of < 5 mm remains,
indicative of a ycN0 stage
4/30/2022 91
FLUID
4/30/2022 92
4/30/2022 93
Contouring mesorectum
4/30/2022 94
1. M: Mesorectum,
2. LLN: Lateral Lymph Nodes
3. EIN: External Iliac Nodes,
4. IN: Inguinal Nodes,
5. IRF: Ischio-Rectal Fossae,
6. SC: Sphincter Complex,
7. IMA: inferior mesenteric artery,
8. SA: sigmoid artery,
9. SRA: superior rectal artery
4/30/2022 95
• https://pubs.rsna.org/do
i/epdf/10.1148/rg.2019180
114
4/30/2022 96
• https://radiologyassistant.nl/abdomen/rectum/rectal-cancer-mr-staging-1
4/30/2022 97
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