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G.Balakrishnan
Assistant Professor
Department of Chemistry
Vivekananda College
4/12/2020 1G.Balakrishnan
OBESITY
4/12/2020 G.Balakrishnan 2
• A country where 270 million people live below the
'poverty line', obesity seems to be a distant issue, meant
for the richkids of first world.
4/12/2020 G.Balakrishnan 3
• India together accounted for 15 per cent of the
world's obese population, with 30 million
obese people, respectively.
4/12/2020 G.Balakrishnan 4
• In 2010, overweight and obesity were
estimated to cause 3 to 4 million deaths, 3.9
per cent of years of life lost, and 3.8 per cent
of disability-adjusted life-years worldwide,
the study said.
4/12/2020 G.Balakrishnan 5
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4/12/2020 G.Balakrishnan 7
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4/12/2020 G.Balakrishnan 9
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4/12/2020 G.Balakrishnan 11
4/12/2020 G.Balakrishnan 12
4/12/2020 G.Balakrishnan 13
4/12/2020 G.Balakrishnan 14
4/12/2020 G.Balakrishnan 15
4/12/2020 G.Balakrishnan 16
CANCER
COME, LET US KNOW IT
BETTER!!
4/12/2020 17G.Balakrishnan
International Facts on ………..
 2nd leading causes of death worldwide.
The number of new cases is expected to rise
by about 70% over the next 2 decades.
http://www.who.int/mediacentre/factsheets/fs297/en/
http://canceratlas.cancer.org/the-burden/
4/12/2020 18G.Balakrishnan
Content
What Is Cancer?
Classification of Tumors
Types of Cancer
Lung cancer
Causes and Risk factors of Lung Cancer
Staging of lung cancer
Symptoms
Diagnose / Treatment
Prevention4/12/2020 G.Balakrishnan 19
What Is Cancer?
Cancer is the uncontrolled growth of cells.
Many types of tumors eventually release cancer
cells that migrate to distant sites in the body,
which they form the secondary tumors know as
metastasis.
http://www.gif2fly.com/Brain%20Cancer%20Cells.
html
https://shawnadieckmann123.wordpress.com/2016/01/07/c
ell-cycle-control-mitosis-and-cancer/
4/12/2020 20G.Balakrishnan
Why is Crab the Symbol of Cancer?
“Cancer” is the Latin word for
crab.
 In its natural habitat, a crab is a
fast, resilient decapod
crustacean that springs to
action and moves in multiple
directions.
 Similarly cancer spreads
from the place at which it
first arose as a primary
tumor to distant locations
in the body.
(source: University of Chicago Radiology
PET-CT department
http://giphy.com/gifs/close-call-crab-car-
wIwrQ3umuEuM8 21
Cancer Cells Versus Normal Cells
22
Classification of Tumors
4/12/2020 23G.Balakrishnan
Types of Cancer
 There are more than 120 types of cancer, characterized by
abnormal cell growth.
Types of cancer are usually named for the organs or tissues
where the cancers form.
4/12/2020 24G.Balakrishnan
4/12/2020 25G.Balakrishnan
http://www.who.int/cancer/country-profiles/ind_en.pdf
xxxxxxxxxxxx
4/12/2020 26G.Balakrishnan
Lung cancer
4/12/2020 27G.Balakrishnan
• What is lung cancer?
Lung cancer results
from abnormal
growth of cells in the
lining of the lungs,
leading to the growth
of a malignant
tumour.
4/12/2020 28G.Balakrishnan
Lung cancer
Respiratory motion as acquired by 4D
CT. The lung tumor to be irradiated is
highlighted in red.
Tobacco smoke contains more than 4,000
chemical compounds
4/12/2020 29G.Balakrishnan
Causes and Risk factors of Lung
Cancer
90% of lung cancers
non-smokers who live
or work with smokers
Other causes of lung
cancer include air
pollution
4/12/2020 30G.Balakrishnan
Stage I : cancer that is confined
to the lung
Stage II: cancer that is confined
to the chest
Stage III: cancer that is confined to
the chest but with larger
and more aggressive tumours
than at stage II
Stage IV: cancer that has spread to
other parts of the body.
Staging of lung cancer
4/12/2020 31G.Balakrishnan
symptoms of lung cancer
1. Persistent cough and hoarseness
2. Shortness of breath
3. wheezing
4. Blood-streaked sputum
5. Chest pain
6. Frequent episodes of bronchitis or
pneumonia
7. Weight loss, weakness, and fatigue.
4/12/2020 32G.Balakrishnan
diagnose lung cancer
1. patient history,
2. physical examination,
3. blood tests,
4. chest x-rays,
5. computerized tomography (CT)
6. positron emission tomography (PET) scans,
7. bone scans,
8. bronchoscopy,
9. cytological studies of sputum,
10. bronchial washings, and fine needle biopsy.
4/12/2020 33G.Balakrishnan
Treatment
• Surgery is the most effective treatment for lung
cancer but only about 20% of lung cancers are
suitable for surgery. (Stage I and II only)
• Radiation therapy may be used for all stages (I-IV)
and is a good option for people are not suitable for
surgery or who refuse surgery.
• Chemotherapy drugs may be given alone or in
combination with surgery or radiation therapy.
4/12/2020 34G.Balakrishnan
 Targeted therapies: These are drugs (gefitinib and erlotinib)
or antibodies (cetuximab, bevacizumab) that block the growth
and spread of cancer by interfering with specific molecules
involved in tumour growth and progression.
Bevacizumab
Cetuximab
Gefitinib
Erlotinib
4/12/2020 35G.Balakrishnan
General side effects
Some side effects of radiotherapy are caused by its
effect on normal tissue in your body. These may
include
1. Tiredness and feeling run down
2. A sore throat and trouble swallowing
3. A cough
4. Hair loss
5. Chest pain
6. A temperature and shivering
7. Feeling sick
8. Sore skin in the treatment area
4/12/2020 36G.Balakrishnan
Prevention is better than cure!!
4/12/2020 37G.Balakrishnan
Avoid
4/12/2020 38G.Balakrishnan
Let us fight cancer!!!!!!
4/12/2020 39G.Balakrishnan
THANK YOU!
4/12/2020 40G.Balakrishnan

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OBESITY

  • 1. G.Balakrishnan Assistant Professor Department of Chemistry Vivekananda College 4/12/2020 1G.Balakrishnan OBESITY
  • 3. • A country where 270 million people live below the 'poverty line', obesity seems to be a distant issue, meant for the richkids of first world. 4/12/2020 G.Balakrishnan 3
  • 4. • India together accounted for 15 per cent of the world's obese population, with 30 million obese people, respectively. 4/12/2020 G.Balakrishnan 4
  • 5. • In 2010, overweight and obesity were estimated to cause 3 to 4 million deaths, 3.9 per cent of years of life lost, and 3.8 per cent of disability-adjusted life-years worldwide, the study said. 4/12/2020 G.Balakrishnan 5
  • 17. CANCER COME, LET US KNOW IT BETTER!! 4/12/2020 17G.Balakrishnan
  • 18. International Facts on ………..  2nd leading causes of death worldwide. The number of new cases is expected to rise by about 70% over the next 2 decades. http://www.who.int/mediacentre/factsheets/fs297/en/ http://canceratlas.cancer.org/the-burden/ 4/12/2020 18G.Balakrishnan
  • 19. Content What Is Cancer? Classification of Tumors Types of Cancer Lung cancer Causes and Risk factors of Lung Cancer Staging of lung cancer Symptoms Diagnose / Treatment Prevention4/12/2020 G.Balakrishnan 19
  • 20. What Is Cancer? Cancer is the uncontrolled growth of cells. Many types of tumors eventually release cancer cells that migrate to distant sites in the body, which they form the secondary tumors know as metastasis. http://www.gif2fly.com/Brain%20Cancer%20Cells. html https://shawnadieckmann123.wordpress.com/2016/01/07/c ell-cycle-control-mitosis-and-cancer/ 4/12/2020 20G.Balakrishnan
  • 21. Why is Crab the Symbol of Cancer? “Cancer” is the Latin word for crab.  In its natural habitat, a crab is a fast, resilient decapod crustacean that springs to action and moves in multiple directions.  Similarly cancer spreads from the place at which it first arose as a primary tumor to distant locations in the body. (source: University of Chicago Radiology PET-CT department http://giphy.com/gifs/close-call-crab-car- wIwrQ3umuEuM8 21
  • 22. Cancer Cells Versus Normal Cells 22
  • 24. Types of Cancer  There are more than 120 types of cancer, characterized by abnormal cell growth. Types of cancer are usually named for the organs or tissues where the cancers form. 4/12/2020 24G.Balakrishnan
  • 28. • What is lung cancer? Lung cancer results from abnormal growth of cells in the lining of the lungs, leading to the growth of a malignant tumour. 4/12/2020 28G.Balakrishnan
  • 29. Lung cancer Respiratory motion as acquired by 4D CT. The lung tumor to be irradiated is highlighted in red. Tobacco smoke contains more than 4,000 chemical compounds 4/12/2020 29G.Balakrishnan
  • 30. Causes and Risk factors of Lung Cancer 90% of lung cancers non-smokers who live or work with smokers Other causes of lung cancer include air pollution 4/12/2020 30G.Balakrishnan
  • 31. Stage I : cancer that is confined to the lung Stage II: cancer that is confined to the chest Stage III: cancer that is confined to the chest but with larger and more aggressive tumours than at stage II Stage IV: cancer that has spread to other parts of the body. Staging of lung cancer 4/12/2020 31G.Balakrishnan
  • 32. symptoms of lung cancer 1. Persistent cough and hoarseness 2. Shortness of breath 3. wheezing 4. Blood-streaked sputum 5. Chest pain 6. Frequent episodes of bronchitis or pneumonia 7. Weight loss, weakness, and fatigue. 4/12/2020 32G.Balakrishnan
  • 33. diagnose lung cancer 1. patient history, 2. physical examination, 3. blood tests, 4. chest x-rays, 5. computerized tomography (CT) 6. positron emission tomography (PET) scans, 7. bone scans, 8. bronchoscopy, 9. cytological studies of sputum, 10. bronchial washings, and fine needle biopsy. 4/12/2020 33G.Balakrishnan
  • 34. Treatment • Surgery is the most effective treatment for lung cancer but only about 20% of lung cancers are suitable for surgery. (Stage I and II only) • Radiation therapy may be used for all stages (I-IV) and is a good option for people are not suitable for surgery or who refuse surgery. • Chemotherapy drugs may be given alone or in combination with surgery or radiation therapy. 4/12/2020 34G.Balakrishnan
  • 35.  Targeted therapies: These are drugs (gefitinib and erlotinib) or antibodies (cetuximab, bevacizumab) that block the growth and spread of cancer by interfering with specific molecules involved in tumour growth and progression. Bevacizumab Cetuximab Gefitinib Erlotinib 4/12/2020 35G.Balakrishnan
  • 36. General side effects Some side effects of radiotherapy are caused by its effect on normal tissue in your body. These may include 1. Tiredness and feeling run down 2. A sore throat and trouble swallowing 3. A cough 4. Hair loss 5. Chest pain 6. A temperature and shivering 7. Feeling sick 8. Sore skin in the treatment area 4/12/2020 36G.Balakrishnan
  • 37. Prevention is better than cure!! 4/12/2020 37G.Balakrishnan
  • 39. Let us fight cancer!!!!!! 4/12/2020 39G.Balakrishnan