This document discusses design-based research and its application to transforming technology use in flexible learning and teaching. It defines design-based research as a pragmatic, grounded, iterative approach to solving real-world educational problems through collaboration between researchers and practitioners. The document provides examples of design-based research projects, including reducing anxiety in hospitalized children and changing assessment culture. It also describes a 5-year Teaching Fellowship Scheme that supported design-based research projects to foster innovation in blended and flexible learning.