Chinese herbal medicine and other traditional Chinese medicine therapies may help reduce side effects from chemotherapy for colorectal cancer. Chemotherapy can deplete healthy qi while treating cancer, worsening side effects, but Chinese medicine aims to nourish qi. Current research shows Chinese medicine may induce cancer cell apoptosis, prevent metastasis, directly relieve symptoms, boost immunity, and increase appetite and recovery. However, more rigorous clinical trials are still needed to fully understand how these treatments work and ensure their safety when combined with chemotherapy.