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Biological Molecules
Prepared by:
MR. KEVIN FRANCIS E. MAGAOAY
Faculty, SHS Biology Department
C h a p t e r 8
Learning Objectives:
 Categorize the biological molecules according to
their structure and function
 Explain the role of each biological molecule in
specific metabolic processes
Overview:
 Definition of Biological Molecules
 Classification of Biological Molecules
 Structure and functions of Biological Molecules
Biological Molecules
 Biomolecules are essential
molecules for all living organisms
 Have unique characteristics and
properties that show how they
contribute to the structure and
function of the cells and how
essential they are in maintaining
life
Elements
The simplest form of a substance
found in the body such as C, H, O, N
Compounds
Made up of two or more elements that
are chemically joined together
Inorganic Compounds
Water, Acid, Bases, Salt, Carbon
Dioxide
Organic Compounds
Carbohydrates, Lipids, Proteins,
Nucleic Acids
Element
 Simplest form of a substance
 Cannot be broken down into more simpler form
 25 out of the natural elements are essential to
life
 98 – 99% of the body is composed of seven
major elements namely C, H, O, N, P, Ca, S
Symbol Name Functions
C Carbon
 Makes up 18% of the
mass of the human
body
 Main component of
organic compounds
H Hydrogen
 10% of human body
mass
 Essential in energy
production
O Oxygen
 61-65% of total
human body mass
 Used for cellular
respiration
Symbol Name Functions
N Nitrogen
 Makes up 3% of
human body mass
 Key element of protein
and nucleic acid
P Phosphorus
 1.2 – 1.5% of human
body mass
 Important for bone
structure
 Major component of
nucleic acid
S Sulfur
 0.20 – 0.25% of
human body mass
 Important components
of proteins
Symbol Name Functions
Ca Calcium
 1.5% of human body
mass
 Gives skeletal system
its rigidity and strength
 Found in bones and
teeth
 Important for muscle
functions
Si, Cl, Mg, Cu, Zn Minerals
 Other elements found
in the body in little
amounts
 Essential for growth
and maintenance of
the body
Symbol Name Functions
Fe & I Trace Elements
 Elements that are
indispensable to life
but is required in
minute amounts
Compounds
 A substance composed of two or more
elements that are chemically bonded together
 Can be classified into inorganic or organic
compounds
 Example: H2O, NaCl
Atomic Bonding
Atomic Bond Description
Covalent Bond
 Sharing of a pair of valence
electrons by two atoms
 Represents sharing of electron
 Done to satisfy the octet rule
Ionic Bond
 Attraction between oppositely
charged atoms (CATIONS,
ANIONS)
 Compounds formed from ionic
bonds are called ionic compounds
or salts
Atomic Bonding
Atomic Bond Description
Hydrogen Bonds
 Electronegativity
 The partial positive charge on
hydrogen atoms that is bonded in
an electronegative atom allows the
hydrogen to be attracted to different
electronegative atoms nearby
 Hydrogen bonds maybe
intramolecular or intermolecular
Atomic Bonding
Atomic Bond Description
Van der Waals Forces
 Weaker than hydrogen bonds
 Occur over a very short distance
 When many of these interactions
occur simultaneously, they can be
powerful
Inorganic Compounds
 Also known as Inorganic Biological Molecules
or Micromolecules
 These are compounds which are those without
carbon
Inorganic
Compounds
Water
Acids
BasesElectrolytes
Carbon
Dioxide
Water
 Versatile solvent
 Dissolves an enormous variety of solutes
necessary for living
 Results from the polarity of its molecules
 When water is in liquid form, its hydrogen
bonds are very weak. The hydrogen bonds
form, break and reform with great frequency
Characteristics and Functions of
Water
 Biological Solvent
Ability to dissolve many substances including
essential molecules in the body
 High Specific Heat
Large amount of heat is needed to increase its
temperature, thus it helps in maintaining the
constant body temperature
Characteristics and Functions of
Water
 High Heat of Vaporization
 Conversion of water from liquid to gaseous state which helps an
organism in preventing dehydration
 High Heat of Fusion
 Helps an organism to maintain constant body temperature at low
temperature
 Medium for Chemical and Physical Process
 Can serve as a place for gas and nutrient exchange and
elimination of wastes
 Means of transport
Acids
 A substance that increases the hydrogen ion
concentration of a solution
 When an acid dissolves in a solution, it donates
hydrogen ions
Weak vs Strong Acids
Base
 A substance that decreases the hydrogen ion
concentration of a solution
 When an acid dissolves in a solution, it accepts
hydrogen ions
pH Scale
Property Acid Base
pH
Less than 7 Greater than 7
Litmus paper
Blue to red Red to blue
Taste
Sour Bitter
Odor
Burning sensation Often no odor
Texture
Sticky Slippery
Reactivity
Reacts with metal to
produce hydrogen gas
Reacts with several fats
and oils
Electrolytes or Salts
 Produced when an acid is combined with a base
 Conducts electricity within the body
Na+OH- + H+Cl- Na+Cl- + H+OH-
Carbon Dioxide
 Essential for plants to perform photosynthesis
 Waste product from the breakdown of glucose
Organic Compounds
 Compounds containing carbon bonded to hydrogen
(hydrocarbon)
 Carbon atom is the backbone of all macromolecules
How to Illustrate Organic Compounds?
 Molecular Formula
How to Illustrate Organic Compounds?
 Structural Formula
Macromolecule
 Macromolecules are large molecules necessary for life
that are built from different combinations of smaller
organic molecules
 Polymers built from monomers such as:
 CHO
 CHON
 CHONP
 CHONPS
Macromolecule
Polymer
A long molecule consisting of many similar or
identical building blocks linked by covalent bonds.
Monomer
The repeating units that serves as a building
blocks of a polymer
Monomer
Monosaccharide - Monomer of Carbohydrates
Amino Acids - Monomer of Proteins
Nucleotides - Monomer of Nucleic Acids
Synthesis of Macromolecules
Dehydration Synthesis
Hydrolysis
Dehydration Synthesis
Monomers combine with each other using
covalent bond to form polymers
Hydrolysis
Polymers are broken down into monomers

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Lesson 8 Introduction to Biological Molecules

  • 1. Biological Molecules Prepared by: MR. KEVIN FRANCIS E. MAGAOAY Faculty, SHS Biology Department C h a p t e r 8
  • 2. Learning Objectives:  Categorize the biological molecules according to their structure and function  Explain the role of each biological molecule in specific metabolic processes
  • 3. Overview:  Definition of Biological Molecules  Classification of Biological Molecules  Structure and functions of Biological Molecules
  • 4. Biological Molecules  Biomolecules are essential molecules for all living organisms  Have unique characteristics and properties that show how they contribute to the structure and function of the cells and how essential they are in maintaining life
  • 5. Elements The simplest form of a substance found in the body such as C, H, O, N Compounds Made up of two or more elements that are chemically joined together Inorganic Compounds Water, Acid, Bases, Salt, Carbon Dioxide Organic Compounds Carbohydrates, Lipids, Proteins, Nucleic Acids
  • 6. Element  Simplest form of a substance  Cannot be broken down into more simpler form  25 out of the natural elements are essential to life  98 – 99% of the body is composed of seven major elements namely C, H, O, N, P, Ca, S
  • 7. Symbol Name Functions C Carbon  Makes up 18% of the mass of the human body  Main component of organic compounds H Hydrogen  10% of human body mass  Essential in energy production O Oxygen  61-65% of total human body mass  Used for cellular respiration
  • 8. Symbol Name Functions N Nitrogen  Makes up 3% of human body mass  Key element of protein and nucleic acid P Phosphorus  1.2 – 1.5% of human body mass  Important for bone structure  Major component of nucleic acid S Sulfur  0.20 – 0.25% of human body mass  Important components of proteins
  • 9. Symbol Name Functions Ca Calcium  1.5% of human body mass  Gives skeletal system its rigidity and strength  Found in bones and teeth  Important for muscle functions Si, Cl, Mg, Cu, Zn Minerals  Other elements found in the body in little amounts  Essential for growth and maintenance of the body
  • 10. Symbol Name Functions Fe & I Trace Elements  Elements that are indispensable to life but is required in minute amounts
  • 11. Compounds  A substance composed of two or more elements that are chemically bonded together  Can be classified into inorganic or organic compounds  Example: H2O, NaCl
  • 12. Atomic Bonding Atomic Bond Description Covalent Bond  Sharing of a pair of valence electrons by two atoms  Represents sharing of electron  Done to satisfy the octet rule Ionic Bond  Attraction between oppositely charged atoms (CATIONS, ANIONS)  Compounds formed from ionic bonds are called ionic compounds or salts
  • 13. Atomic Bonding Atomic Bond Description Hydrogen Bonds  Electronegativity  The partial positive charge on hydrogen atoms that is bonded in an electronegative atom allows the hydrogen to be attracted to different electronegative atoms nearby  Hydrogen bonds maybe intramolecular or intermolecular
  • 14. Atomic Bonding Atomic Bond Description Van der Waals Forces  Weaker than hydrogen bonds  Occur over a very short distance  When many of these interactions occur simultaneously, they can be powerful
  • 15. Inorganic Compounds  Also known as Inorganic Biological Molecules or Micromolecules  These are compounds which are those without carbon
  • 17. Water  Versatile solvent  Dissolves an enormous variety of solutes necessary for living  Results from the polarity of its molecules  When water is in liquid form, its hydrogen bonds are very weak. The hydrogen bonds form, break and reform with great frequency
  • 18. Characteristics and Functions of Water  Biological Solvent Ability to dissolve many substances including essential molecules in the body  High Specific Heat Large amount of heat is needed to increase its temperature, thus it helps in maintaining the constant body temperature
  • 19. Characteristics and Functions of Water  High Heat of Vaporization  Conversion of water from liquid to gaseous state which helps an organism in preventing dehydration  High Heat of Fusion  Helps an organism to maintain constant body temperature at low temperature  Medium for Chemical and Physical Process  Can serve as a place for gas and nutrient exchange and elimination of wastes  Means of transport
  • 20. Acids  A substance that increases the hydrogen ion concentration of a solution  When an acid dissolves in a solution, it donates hydrogen ions
  • 21. Weak vs Strong Acids
  • 22. Base  A substance that decreases the hydrogen ion concentration of a solution  When an acid dissolves in a solution, it accepts hydrogen ions
  • 24. Property Acid Base pH Less than 7 Greater than 7 Litmus paper Blue to red Red to blue Taste Sour Bitter Odor Burning sensation Often no odor Texture Sticky Slippery Reactivity Reacts with metal to produce hydrogen gas Reacts with several fats and oils
  • 25. Electrolytes or Salts  Produced when an acid is combined with a base  Conducts electricity within the body Na+OH- + H+Cl- Na+Cl- + H+OH-
  • 26. Carbon Dioxide  Essential for plants to perform photosynthesis  Waste product from the breakdown of glucose
  • 27. Organic Compounds  Compounds containing carbon bonded to hydrogen (hydrocarbon)  Carbon atom is the backbone of all macromolecules
  • 28. How to Illustrate Organic Compounds?  Molecular Formula
  • 29. How to Illustrate Organic Compounds?  Structural Formula
  • 30. Macromolecule  Macromolecules are large molecules necessary for life that are built from different combinations of smaller organic molecules  Polymers built from monomers such as:  CHO  CHON  CHONP  CHONPS
  • 31. Macromolecule Polymer A long molecule consisting of many similar or identical building blocks linked by covalent bonds. Monomer The repeating units that serves as a building blocks of a polymer
  • 32. Monomer Monosaccharide - Monomer of Carbohydrates Amino Acids - Monomer of Proteins Nucleotides - Monomer of Nucleic Acids
  • 34. Dehydration Synthesis Monomers combine with each other using covalent bond to form polymers
  • 35. Hydrolysis Polymers are broken down into monomers