AMINO ACID AND LIPID METABOLISM BY VANA JAGAN MOHAN RAO

1. BY
VANA JAGAN MOHAN RAO M.S.Pharm, MED.CHEM
NIPER-KOLKATA
Asst.Professor, MIPER-KURNOOL
Email: jaganvana6@gmail.com

2. CONTENTS
PROTEIN METABOLISM
CLASSIFICATION AND FUNCTIONS OF PROTEINS
DIGESTION AND ABSORPTION OF PROTEINS
METABOLISM OF AMINOACIDS (TRANSAMINATION &
DEAMINATION)
UREA CYCLE
LIPID METABOLISM
CLASSIFICATION AND FUNCTIONS OF LIPIDS
DIGESTION AND ABSORPTION OF LIPIDS
METABOLISM OF LIPIDS (BETA OXIDATION)
KETONE BODIES
FORMATION (KETOGENESIS)
BREAKDOWN (KETOLYSIS)
BIOSYNTHESIS OF CHOLESTEROL AND STEROID HORMONES

3. PROTEIN METABOLISM
V.JAGAN MOHAN RAO M.S.Pharm., MED.CHEM
NIPER-KOLKATA
Asst.Professor, MIPER-KURNOOL
EMAIL- jaganvana6@gmail.com

4. PROTEINS
Proteins are naturally occurring macromolecules made up of
repeating units of L-amino acids.
There are around 20 different amino acids which are
categorized as essential amino acids and non-essential amino
acids.
Essential amino acids are those which cannot be synthesized
by the body and thus have to be provided from the diet.
Essential amino acids include Valine, Leucine, Isoleucine,
Phenylalanine, Tryptophan, Threonine, Methionine, Arginine,
Lysine and Histidine.
Non-essential amino acids are synthesized by the body.
Non-essential amino acids include Alanine, Arginine,
Asparagine, Aspartic acid, Cysteine, Glutamic acid, Glutamine,
Glycine, Proline, Serine, Tyrosine

5. STRUCTURES OF AMINOACIDS

6. CLASSIFICATION OF PROTEINS

7. CLASSIFICATION OF PROTEINS

8. CLASSIFICATION OF PROTEINS

9. FUNCTIONS OF PROTEINS

10. DIGESTION & ABSORPTION OF PROTEINS

11. DIGESTION & ABSORPTION OF PROTEINS

12. DIGESTION & ABSORPTION OF PROTEINS

13. REACTIONS OF AMINOACIDS
TRANSAMINATION: It is an exchange of functional groups
between any amino acid (except Lysine, Proline, Threonine) and
an α-keto acid.
The amino group is usually transferred to the keto acid to new
amino acid.
Ex: Pyruvate---------------------Alanine
Oxaloacetate --------------- Aspartate
α-Keto glutarate -----------Glutamate

16. REACTIONS OF AMINOACIDS
DEAMINATION: Elimination of amino group from amino
acid with ammonia formation.
TYPES OF DEAMINATION:
OXIDATIVE DEAMINATION
REDUCTIVE DEAMINATION
HYDROLYTIC DEAMINATION
INTRAMOLECULAR DEAMINATION

18. OXIDATIVE DEAMINATION

24. LIPID METABOLISM
V.JAGAN MOHAN RAO M.S.Pharm., MED.CHEM
NIPER-KOLKATA
Asst.Professor, MIPER-KURNOOL
EMAIL- jaganvana6@gmail.com

25. LIPIDS
Lipids are a variety group of biomolecules that contains
hydrophobic portion in its structure.
Lipids play many roles in body, that includes
constituents of cell membrane (Glycerolipids, Sphingolipids, Cholesterol)
Energy storage
Hormones (steroids)
Vitamins (Fat-soluble)
Oxygen/Electron carrier (Heme)

26. CLASSIFICATION OF LIPIDS

27. FUNCTIONS OF LIPIDS

29. DIGESTION & ABSORPTION OF LIPIDS

30. BETA OXIDATION OF FATTYACIDS

47. CONVERSION OF CHOLESTEROL INTO STEROID
HORMONES