This document analyzes the water quality assessment in Hyderabad, India in terms of the Water Quality Index (WQI) using remote sensing and GIS techniques. Water samples were collected from various locations and analyzed for physio-chemical parameters to generate an attribute database. The WQI was calculated based on parameters like pH, hardness, TDS, chlorides, sulfates, nitrates, carbonates, and bicarbonates. Spatial distribution maps of WQI were generated for pre- and post-monsoon periods from 2006 to 2011. The WQI analysis helped classify water samples as excellent, good, poor, very poor, or unfit. The spatial maps can aid long-term water resource monitoring.