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Derivatives
Front onasal
Forehead,
Bridge of nose,
Medial nasal (P) Philt rum of upper lip,
Crest & t ip of nose
Lat eral nasal (P) Alae of nose
www.indiandentalacademy.com
Cheeks,
lat eral port ion of upper lip &
UPPER J AW
Lower lip & LOWER J AW
Maxillary process
Mandibular process
www.indiandentalacademy.com
Formation of Face
www.indiandentalacademy.com
Anomalies of face
Def ect s of rhomboencephalic organizing cent er,
account f or dysmorphology of middle & lower 3rd
of
f ace.
Facial clefts
www.indiandentalacademy.com
Development of palate
www.indiandentalacademy.com
Prenatal development
Palate
Format ion of primary and secondary palat e
Elevat ion of palat al shelves
Fusion of palat al shelves
www.indiandentalacademy.com
Intermaxillary segment
Formed by mer ging of t he 2 medial nasal
pr ocesses
I t is composed of –
a) Labial component - f orms PHI LTRUM
b) Upper j aw component - carries 4 MAX.I NCI SORS
c) Palat al component - f orms PRI MARY PALATE
www.indiandentalacademy.com
Primary palate
Front onasal process
Medial nasal
Mesenchyme
Wedge shaped mass
bet ween int ernal
surf ace of maxillar y
prominence
Primary palat e
www.indiandentalacademy.com
Secondary palate
6th
week– 2 lat eral palat al shelves develops
Secondary nasal sept um grows
7th
week– palat al shelves grow & lie vert ically
www.indiandentalacademy.com
8th
week IUL
St omodeum enlarges
Tongue drops
Vert ically inclined palat al shelves -horizont al
Shelves cont act each ot her in midline
By 12th
week, f usion of palat al processes is complet e
www.indiandentalacademy.com
To summarize…
Maxillary prominence
2 horizont al mesenchymal proj ect ions
6t h
week Lat eral palat ine process
Fuse-
Wit h each ot her -12t h
week
Primary palat e
Nasal sept um
Secondary palat e
www.indiandentalacademy.com
www.indiandentalacademy.com
Elevation of palatal shelves-8th
Elevat ion of palat al shelves
Muscular
movement
Pressure
dif f erences
Biomechanical
t ransf ormat ion of
connect ive t issue
mat rix
I nt rinsic
shelf f orce
Dif f erent ial
mit ot ic growt h
Wit hdrawal of
embryo’s f ace
Vascular
changes
I ncrease in t issue
Tur ger
www.indiandentalacademy.com
Theories of palatal shelf elevation
EXTRINSIC FORCES
 Descent of t ongue
 Myoneural act ivit y wit h in t ongue
 Shelves pushed up by t ongue
 Mout h opening ref lexes
www.indiandentalacademy.com
Theories of palatal shelf elevation
INTRINSICFORCES
Hydr at ion and polymerisat ion of int ercellular subst ance
Dif f erent ial growt h on one side of palat al shelf
Turgor produced by build up of HYALURONI C ACI D
SEROTONI N release f r om neural t issue.
Mesenchymal cell biosynt het ic act ivit y
Changing amount s of GLYCOSAMI NOGLYCANS(GAG)
www.indiandentalacademy.com
Palatal Fusion
(occlusal view)
www.indiandentalacademy.com
Palatal Fusion
(Frontal view)
www.indiandentalacademy.com
Ossification of palate
8t h
wk
10t h
wk
Childhood
12- 14
years
Premaxillary cent res
Primary ossif icat ion cent res of each palat ine bone
Y shaped midpalat al sut ure
T shaped midpalat al sut ure
No ossif icat ion at t he sof t palat e region
Mid palat ine sut ure ossif ies
www.indiandentalacademy.com
Growth in dimensions-palate
Pre nat al lif e (apposit ional growt h in t he
alveolar margin)
lengt h > widt h
At birt h (apposit ional growt h in t he maxillary
t uberosit y)
lengt h = widt h
Post nat al lif e
widt h > lengt h
www.indiandentalacademy.com
Growth in dimensions-palate
Lengt h increases - 7-18 weeks I UL
Widt h increases - 4th
mont h onwards
height
widt h
lengt h
Arched palat e
Lat eral alveolar process t oget her wit h a concave
f loor produced by t ongue – palat al t unnel t o
receive a nipple
Thumb and f inger sucking- accent uat ed palat al
f urrow
www.indiandentalacademy.com
Anomalies of palate
www.indiandentalacademy.com
Anomalies of palate
28t h – 38t h day – Primary palat e  Clef t lip
&/ or palat e and ot her Facial Clef t s
42nd -55t h day – Secondary palat e  Clef t
palat e
Shelf elevat ion and f usion begins earlier in
males- account ing sex dif f erences in incidence.
5 TH
week
I UL
12 TH
week I UL6 9
CRITICALPERIOD
www.indiandentalacademy.com
Palatal clefts
Def ect ive f usion of various component s of palat e
Causes:
Def ect ive shelf f usion
Failure of shelves t o elevat e
Failure of t ongue t o drop f rom b/ w shelves
Smallness of shelves
I nhibit ion of f usion process it self
Delayed elevat ion of shelves
Failure of medial edge epit helial cell deat h
www.indiandentalacademy.com
Palatal clefts
www.indiandentalacademy.com

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Growth and development

  • 1. Derivatives Front onasal Forehead, Bridge of nose, Medial nasal (P) Philt rum of upper lip, Crest & t ip of nose Lat eral nasal (P) Alae of nose www.indiandentalacademy.com
  • 2. Cheeks, lat eral port ion of upper lip & UPPER J AW Lower lip & LOWER J AW Maxillary process Mandibular process www.indiandentalacademy.com
  • 4. Anomalies of face Def ect s of rhomboencephalic organizing cent er, account f or dysmorphology of middle & lower 3rd of f ace. Facial clefts www.indiandentalacademy.com
  • 6. Prenatal development Palate Format ion of primary and secondary palat e Elevat ion of palat al shelves Fusion of palat al shelves www.indiandentalacademy.com
  • 7. Intermaxillary segment Formed by mer ging of t he 2 medial nasal pr ocesses I t is composed of – a) Labial component - f orms PHI LTRUM b) Upper j aw component - carries 4 MAX.I NCI SORS c) Palat al component - f orms PRI MARY PALATE www.indiandentalacademy.com
  • 8. Primary palate Front onasal process Medial nasal Mesenchyme Wedge shaped mass bet ween int ernal surf ace of maxillar y prominence Primary palat e www.indiandentalacademy.com
  • 9. Secondary palate 6th week– 2 lat eral palat al shelves develops Secondary nasal sept um grows 7th week– palat al shelves grow & lie vert ically www.indiandentalacademy.com
  • 10. 8th week IUL St omodeum enlarges Tongue drops Vert ically inclined palat al shelves -horizont al Shelves cont act each ot her in midline By 12th week, f usion of palat al processes is complet e www.indiandentalacademy.com
  • 11. To summarize… Maxillary prominence 2 horizont al mesenchymal proj ect ions 6t h week Lat eral palat ine process Fuse- Wit h each ot her -12t h week Primary palat e Nasal sept um Secondary palat e www.indiandentalacademy.com
  • 13. Elevation of palatal shelves-8th Elevat ion of palat al shelves Muscular movement Pressure dif f erences Biomechanical t ransf ormat ion of connect ive t issue mat rix I nt rinsic shelf f orce Dif f erent ial mit ot ic growt h Wit hdrawal of embryo’s f ace Vascular changes I ncrease in t issue Tur ger www.indiandentalacademy.com
  • 14. Theories of palatal shelf elevation EXTRINSIC FORCES  Descent of t ongue  Myoneural act ivit y wit h in t ongue  Shelves pushed up by t ongue  Mout h opening ref lexes www.indiandentalacademy.com
  • 15. Theories of palatal shelf elevation INTRINSICFORCES Hydr at ion and polymerisat ion of int ercellular subst ance Dif f erent ial growt h on one side of palat al shelf Turgor produced by build up of HYALURONI C ACI D SEROTONI N release f r om neural t issue. Mesenchymal cell biosynt het ic act ivit y Changing amount s of GLYCOSAMI NOGLYCANS(GAG) www.indiandentalacademy.com
  • 18. Ossification of palate 8t h wk 10t h wk Childhood 12- 14 years Premaxillary cent res Primary ossif icat ion cent res of each palat ine bone Y shaped midpalat al sut ure T shaped midpalat al sut ure No ossif icat ion at t he sof t palat e region Mid palat ine sut ure ossif ies www.indiandentalacademy.com
  • 19. Growth in dimensions-palate Pre nat al lif e (apposit ional growt h in t he alveolar margin) lengt h > widt h At birt h (apposit ional growt h in t he maxillary t uberosit y) lengt h = widt h Post nat al lif e widt h > lengt h www.indiandentalacademy.com
  • 20. Growth in dimensions-palate Lengt h increases - 7-18 weeks I UL Widt h increases - 4th mont h onwards height widt h lengt h Arched palat e Lat eral alveolar process t oget her wit h a concave f loor produced by t ongue – palat al t unnel t o receive a nipple Thumb and f inger sucking- accent uat ed palat al f urrow www.indiandentalacademy.com
  • 22. Anomalies of palate 28t h – 38t h day – Primary palat e  Clef t lip &/ or palat e and ot her Facial Clef t s 42nd -55t h day – Secondary palat e  Clef t palat e Shelf elevat ion and f usion begins earlier in males- account ing sex dif f erences in incidence. 5 TH week I UL 12 TH week I UL6 9 CRITICALPERIOD www.indiandentalacademy.com
  • 23. Palatal clefts Def ect ive f usion of various component s of palat e Causes: Def ect ive shelf f usion Failure of shelves t o elevat e Failure of t ongue t o drop f rom b/ w shelves Smallness of shelves I nhibit ion of f usion process it self Delayed elevat ion of shelves Failure of medial edge epit helial cell deat h www.indiandentalacademy.com