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MICI 1100 Health Sciences Microbiology Course Coordinator: Dr David Haldane Rm 326 Mackenzie Building, QE II HSC [email_address] Welcome to
Objectives of the Course ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Milestones in Microbiology ,[object Object],[object Object],[object Object],Edward Jenner (1749 - 1823) Anthon van Leeuwenhoek (1632-1723)
Milestones (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Milestones in Microbiology (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Koch's postulates - to establish if an organism is the cause of a disease ,[object Object],[object Object],[object Object],[object Object]
Organisms - Morphology (shapes) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Staphylococci Streptococci Rods Vibrio Bacterial Morphology
Spirochaetes Cocco-bacilli Branching Filaments Branching Rods More Bacterial Morphology
Structures of Bacteria ,[object Object],[object Object],[object Object],[object Object]
Appendages - project from the cell ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Flagella - Arrangements
Appendages - project from the cell (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Appendages to Bacterial Cells
Surface and Cell Wall ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Surface and Cell Wall (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Surface and Cell Wall (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Surface and Cell Wall (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Surface and Cell Wall (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other Structures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bacterial Taxonomy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Bacterial Taxonomy (cont’d) ,[object Object]
 
 
Bacterial Taxonomy ( cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
General Groupings used in Taxonomy ,[object Object],[object Object],[object Object],[object Object]
Staining Organisms ,[object Object],[object Object],[object Object],[object Object],[object Object]
Complex Stains ,[object Object],[object Object]
The Gram Stain ,[object Object],[object Object],[object Object],[object Object]
Method for Gram Stain ,[object Object],[object Object],[object Object],[object Object],[object Object]
a
Acid Fast Stain ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bacterial Growth Requirements and Metabolism
Requirements for Bacterial Growth ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Requirements for Bacterial Growth (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Requirements for Bacterial Growth (cont'd) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Requirements for Bacterial Growth (cont'd) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Requirements for Bacterial Growth (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Growth of Bacteria ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Phases of Growth of Microbial Populations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phases of Growth of Microbial Populations (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phases of Bacterial Growth
Metabolism ,[object Object],[object Object],[object Object],[object Object],[object Object],ATP
Metabolism (cont'd) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Starch
Importation of Nutrients ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Importation of Nutrients (cont’d) ,[object Object],[object Object],[object Object]
[object Object],Glycolysis
[object Object],[object Object],[object Object],[object Object],Respiration
Catabolism ,[object Object],[object Object]
[object Object],[object Object]
 
 
Other Catabolism ,[object Object],[object Object]
 
 
Sterilization and Disinfection
Disinfection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Disinfection (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Examples of Disinfectants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Examples of Disinfectants (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Examples of Disinfectants (cont’d) ,[object Object],[object Object]
“High Level Disinfectants” ,[object Object],[object Object],[object Object],[object Object]
Sterilization ,[object Object],[object Object]
Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Autoclaving ,[object Object],[object Object],[object Object]
Gas ,[object Object],[object Object]
Radiation ,[object Object]
Bacterial Pathogenicity Virulence Factors and Genetics
Microbial Ecology ,[object Object],[object Object],[object Object],[object Object]
Microbial Ecology (cont’d) ,[object Object],[object Object]
Transmission of Infection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transmission of Infection (cont’d) ,[object Object],[object Object],[object Object]
Virulence Factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Virulence Factors (cont’d) ,[object Object],[object Object],[object Object],[object Object]
Virulence Factors (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Virulence Factor (cont’d) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Virulence Factors (cont’d) ,[object Object],[object Object],[object Object],[object Object]
Bacterial Genetics ,[object Object],[object Object],[object Object]
Bacterial Genetics (cont’d) ,[object Object],[object Object]
DNA Transfer ,[object Object],[object Object],[object Object],[object Object]
DNA Transfer (cont’d) ,[object Object],[object Object],[object Object]

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