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Microbiology  Chapter 1
Part I  Introduction to Microbiology
Scope of Microbiology  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prokaryotic vs. Eukaryotic
Assigning Characteristics  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Assign common characteristics to each group
(Top) Coccidioidomycosis Arthrospores  (Bottom) Development of Arthrospores  Into spherule in lung tissue Fungal Infection of the lung Schistosoma (worms) at  two different stages of  development – liver  Disease and other symptoms  Staphylococcus Aureus Gram positive bacteria Staph infections and MRSA Trypanosoma  Eukaryotic pathogen African Sleeping Sickness Treponema pallidum Bacterial spirochete Causes syphilis Mycobacterium tuberculosis.  Acid fast bacteria (shown in pink) like this causes TB and leprosy.  Light blue is Staph epi, a common bacteria cocci which inhabits the Skin.  Not a common pathogen  Herpes Virus
Size Comparisons
What Do  Microbes Do? Photosynthesis Decomposition Soil Fertility &  Microbial  Ecology  Microbial  Physiology &  Fermentation of Cheese Wine Bread Genetics,  Gene  Regulation  &  Biotechnology  Bioremediation  Oil Eating  Bacteria &  Fungi Water  Purification  Infectious  Disease &  Immunology Ch 4, 7, & 26 Ch 8 & 27 Ch 9 & 10 Ch 27 Briefly  Need an  Environmental  & Applied  Micro  Course  Ch 14 – 16 &  Ch 18 - 25
Part II  Historical Figures in Microbiology
Superstition of Microbiology  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
First Look at Microbes  ,[object Object],[object Object],[object Object],[object Object]
Abiogenesis vs. Biogenesis ,[object Object],[object Object]
Abiogenesis vs. Biogenesis ,[object Object],[object Object],[object Object],[object Object]
Proving that Microbes Are Present in Dust Particles  ,[object Object],[object Object]
Proving that Microbes Are Present in Dust Particles ,[object Object],[object Object],[object Object],[object Object]
[object Object],Proving that Microbes Are Present in Dust Particles
Pasteurization ,[object Object]
Lister’s Work ,[object Object],[object Object],[object Object],[object Object]
Koch’s Postulates ,[object Object],[object Object]
Koch’s Postulates Mouse dies with sores Take scraping and plate on agar A heterogeneous population of bacteria Grow – which one is the causative agent Isolate all different strains and types and  inject into healthy mice and see which mice develop similar phenotype and symptoms Take a sample again from mice which died of same symptoms and isolate the  causative agent again
Koch’s Postulates A sequence of experimental steps to relate a specific microbe to a specific disease
Koch’s Postulates Used to prove the  specific causative  agent of an infectious  disease
Jenner’s Work ,[object Object],[object Object],[object Object],[object Object],[object Object]
Alexander Fleming’s Work ,[object Object],[object Object],[object Object],[object Object]
Germ Theory of Disease ,[object Object],[object Object],[object Object]
Part III  Introduction to Disease
Chronic vs. Infectious Disease  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conquering Infectious Disease  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conquering Infectious Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
All Diseases  Old Standards Syphilis Measles Staph Infections Chicken Pox Emerging Avia Flu Antigenic shift event HIV in the 80’s West Nile in US in 2001 Continental travel  Reemerging Tuberculosis - TB New drug  resistant strains  Immunocompromised  patients
Top Causes of Death * Stands for lower respiratory disease Infectious Diseases are shown in  red 1.19 x 10 6 10. Accidents  33,865 10.Septicemia  1.27 x 10 6 9.  Malaria 40,970 9. Kidney problems 1.57 x 10 6 8.  Tuberculosis 58,870 8. Alzheimer disease 1.80 x 10 6 7.  Diarrheal disease 65,680 7. Flu & Pneumonia 2.75 x 10 6 6.  Chronic LRD* 73,250 6. Diabetes 2.78 x 10 6 5.  HIV/AIDS 106,740 5. Accidents 3.33 x 10 6 4.  Cancer 124,800 4. Chronic LRD* 3.88 x 10 6 3.  Res infection   162,670 3. Stroke 5.51 x 10 6 2.  Stroke 557,270 2. Cancer 8.12 x 10 6 1.  Heart Disease 696,950 1. Heart Disease Deaths Worldwide Deaths United States
Infectious  Disease  Statistics
Part IV Taxonomy & Biological Classification
Organizing Life ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Taxonomy  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Taxonomy
Nomenclature  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Nomenclature  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Evolution & Phylogeny  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Whittaker’s  System
Whittaker’s System  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Solution to Whittaker’s Tree ,[object Object],[object Object],[object Object],[object Object],[object Object]
Three Domain System

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Microbiology ch 1

  • 2. Part I Introduction to Microbiology
  • 3.
  • 5.
  • 6. (Top) Coccidioidomycosis Arthrospores (Bottom) Development of Arthrospores Into spherule in lung tissue Fungal Infection of the lung Schistosoma (worms) at two different stages of development – liver Disease and other symptoms Staphylococcus Aureus Gram positive bacteria Staph infections and MRSA Trypanosoma Eukaryotic pathogen African Sleeping Sickness Treponema pallidum Bacterial spirochete Causes syphilis Mycobacterium tuberculosis. Acid fast bacteria (shown in pink) like this causes TB and leprosy. Light blue is Staph epi, a common bacteria cocci which inhabits the Skin. Not a common pathogen Herpes Virus
  • 8. What Do Microbes Do? Photosynthesis Decomposition Soil Fertility & Microbial Ecology Microbial Physiology & Fermentation of Cheese Wine Bread Genetics, Gene Regulation & Biotechnology Bioremediation Oil Eating Bacteria & Fungi Water Purification Infectious Disease & Immunology Ch 4, 7, & 26 Ch 8 & 27 Ch 9 & 10 Ch 27 Briefly Need an Environmental & Applied Micro Course Ch 14 – 16 & Ch 18 - 25
  • 9. Part II Historical Figures in Microbiology
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20. Koch’s Postulates Mouse dies with sores Take scraping and plate on agar A heterogeneous population of bacteria Grow – which one is the causative agent Isolate all different strains and types and inject into healthy mice and see which mice develop similar phenotype and symptoms Take a sample again from mice which died of same symptoms and isolate the causative agent again
  • 21. Koch’s Postulates A sequence of experimental steps to relate a specific microbe to a specific disease
  • 22. Koch’s Postulates Used to prove the specific causative agent of an infectious disease
  • 23.
  • 24.
  • 25.
  • 26. Part III Introduction to Disease
  • 27.
  • 28.
  • 29.
  • 30. All Diseases Old Standards Syphilis Measles Staph Infections Chicken Pox Emerging Avia Flu Antigenic shift event HIV in the 80’s West Nile in US in 2001 Continental travel Reemerging Tuberculosis - TB New drug resistant strains Immunocompromised patients
  • 31. Top Causes of Death * Stands for lower respiratory disease Infectious Diseases are shown in red 1.19 x 10 6 10. Accidents 33,865 10.Septicemia 1.27 x 10 6 9. Malaria 40,970 9. Kidney problems 1.57 x 10 6 8. Tuberculosis 58,870 8. Alzheimer disease 1.80 x 10 6 7. Diarrheal disease 65,680 7. Flu & Pneumonia 2.75 x 10 6 6. Chronic LRD* 73,250 6. Diabetes 2.78 x 10 6 5. HIV/AIDS 106,740 5. Accidents 3.33 x 10 6 4. Cancer 124,800 4. Chronic LRD* 3.88 x 10 6 3. Res infection 162,670 3. Stroke 5.51 x 10 6 2. Stroke 557,270 2. Cancer 8.12 x 10 6 1. Heart Disease 696,950 1. Heart Disease Deaths Worldwide Deaths United States
  • 32. Infectious Disease Statistics
  • 33. Part IV Taxonomy & Biological Classification
  • 34.
  • 35.
  • 37.
  • 38.
  • 39.
  • 41.
  • 42.