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Cellular Transport
          ‘07 Biology
2 Types:
Active        Passive
Energy!       No energy!
Passive Transport
Substances are allowed to cross the cell
 membrane without any input of energy
Remember: The cell membrane is
 “selectively permeable”



                      QuickTimeª and a
           TIFF (Uncompressed) decompressor
              are needed to see this picture.
Types of Passive Transport
Diffusion
Facilitated Diffusion
Osmosis
Diffusion
Movement of molecules from areas of
 high concentration to low
How does it work?
“Kinetic energy” (energy in motion)
Concentration gradient- caused by a
 difference in concentration
Diffusion results in equilibrium  (all
 molecules occupy the same amount of
 space)
Facilitated Diffusion
Some molecules are helped across the
 cell membrane by carrier proteins
No energy is required in this process



                         QuickTimeª and a
              TIFF (Uncompressed) decompressor
                 are needed to see this picture.
Osmosis
The diffusion of water across the
 cell membrane
The direction of osmosis depends
 on the concentration of solutes
 inside and outside the cell
Osmosis (continued)
Hypotonic- concentration of solutes
 outside the cell is lower than the
 concentration inside
Hypertonic- concentration outside is
 higher than inside
Isotonic- concentrations inside and out
 are equal
Direction of Osmosis



              QuickTimeª and a
   TIFF (Uncompressed) decompressor
      are needed to see this picture.
Active Transport
Sometimes cells must move molecules
 against the concentration gradient
This process requires energy (ATP)
 and special protein “pumps”
Sodium-Potassium Pump
Special proteins within the membrane
 that transport Na+ and K- ions
Some cells must have a higher
 concentration of Na+ ions outside of
 the cell and a higher concentration of
 K- ions inside the cell
2 Potassiums are brought in for every 3
 Sodiums removed
Sodium-Potassium Pump




                 QuickTimeª and a
      TIFF (Uncompressed) decompressor
         are needed to see this picture.
Movement In Vesicles
Some molecules are too big to be
 transported across the cell membrane
 by passive and active transport
Endocytosis- “cell eating”
Exocytosis- “cell pooping”
Endocytosis
Process by which cells ingest
 macromolecules, fluids, large particles
 and even other cells
These molecules are enclose in a
 bubble of membrane (vesicle) that
 pinches away from the cell membrane
Endocytosis (continued)
Pinocytosis- ingestion of small
 particles and fluid
Phagocytosis- ingestion of large
 molecules or other cells


                             QuickTimeª and a
                  TIFF (Uncompressed) decompressor
                     are needed to see this picture.
Exocytosis
Process by which waste and large
 particles are released from the cell
A vesicle will fuse with the membrane,
 releasing its contents into the extra
 cellular environment
Endocytosis/Exocytosis



                 QuickTimeª and a
      TIFF (Uncompressed) decompressor
         are needed to see this picture.

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Passivetransport 090810143312-phpapp01

  • 1. Cellular Transport ‘07 Biology
  • 2. 2 Types: Active Passive Energy! No energy!
  • 3. Passive Transport Substances are allowed to cross the cell membrane without any input of energy Remember: The cell membrane is “selectively permeable” QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture.
  • 4. Types of Passive Transport Diffusion Facilitated Diffusion Osmosis
  • 5. Diffusion Movement of molecules from areas of high concentration to low How does it work? “Kinetic energy” (energy in motion) Concentration gradient- caused by a difference in concentration Diffusion results in equilibrium (all molecules occupy the same amount of space)
  • 6. Facilitated Diffusion Some molecules are helped across the cell membrane by carrier proteins No energy is required in this process QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture.
  • 7. Osmosis The diffusion of water across the cell membrane The direction of osmosis depends on the concentration of solutes inside and outside the cell
  • 8. Osmosis (continued) Hypotonic- concentration of solutes outside the cell is lower than the concentration inside Hypertonic- concentration outside is higher than inside Isotonic- concentrations inside and out are equal
  • 9. Direction of Osmosis QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture.
  • 10. Active Transport Sometimes cells must move molecules against the concentration gradient This process requires energy (ATP) and special protein “pumps”
  • 11. Sodium-Potassium Pump Special proteins within the membrane that transport Na+ and K- ions Some cells must have a higher concentration of Na+ ions outside of the cell and a higher concentration of K- ions inside the cell 2 Potassiums are brought in for every 3 Sodiums removed
  • 12. Sodium-Potassium Pump QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture.
  • 13. Movement In Vesicles Some molecules are too big to be transported across the cell membrane by passive and active transport Endocytosis- “cell eating” Exocytosis- “cell pooping”
  • 14. Endocytosis Process by which cells ingest macromolecules, fluids, large particles and even other cells These molecules are enclose in a bubble of membrane (vesicle) that pinches away from the cell membrane
  • 15. Endocytosis (continued) Pinocytosis- ingestion of small particles and fluid Phagocytosis- ingestion of large molecules or other cells QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture.
  • 16. Exocytosis Process by which waste and large particles are released from the cell A vesicle will fuse with the membrane, releasing its contents into the extra cellular environment
  • 17. Endocytosis/Exocytosis QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture.

Editor's Notes

  1. What is meant by the word transport? Moving substances across the cell membrane
  2. What is the cell membrane made of? Lipids make it polar--> oxygen and co2 can readily pass through Small molecules can pass through protein pores
  3. Spray aerosol into the corner of the classroom Kinetic energy --> Particles are constantly moving and bumping into each other Start a mosh pit in the corner of the classroom In the absence of outside influence diffusion will continue until equilibrium is reached
  4. Molecules may be too large or not soluble in lipids --> glucose
  5. Hypotonic solutions are good Cells adapt by pumping water or solutes out of the cytosol (contractile vacuoles or solute pumps) Plants love hypotonic environments --> turgor pressure Hypertonic solutions are bad…emkay Results in the loss of water --> plasmolysis Some cells cannot adjust to changes in environment (rbc’s) --> cytolysis or “cell bursting “ may result
  6. Macromolecules, nutrients, large quantities of small molecules
  7. The vesicles then fuse with other membrane bound organelles within the cell
  8. Phagocytosis can be used to ingest bacteria or viruses that invade the body! Pic --> white blood cell ingestng bacteria