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In the Name of Allah , The Most
Gracious , The Most Merciful
Topic
Bioenergetics and
energy produced in
TCA cycle.

By :- Abdul Qahar
Bioenergetics
• Bioenergetics is the subject of a field of
biochemistry that concerns energy flow through
living systems.
Bioenergetics
• It is the part of biochemistry

• Concerned with the energy
• In a living organism, chemical bonds are broken
Bioenergetics
• Living organisms obtain energy
• For example, lithotrophs
Bioenergetics
• Materials generally combined with oxygen.

• Can also be oxidized an aerobically.
Bioenergetics
• Living organism produce ATP.
• The energy got through the hydrolysis of ATP is
used as a battery.
Exergonic
• Exergonic

releases energy.

• It is thermodynamically favored.
• The release of energy is negative and equal to
- ΔG.
Endergonic
• Endergonic

consumes energy.

• It has a positive ΔG
Cotransport
• In August 1960, Robert K.
• Discovery of the sodium-glucose cotransport as
the mechanism for intestinal glucose absorption.
Energy balance

Energy intake

internal heat produced +
external work + storage.
Bio medical importance
• Bioenergetics is the study of the energy changes
accompanying biochemical reactions. Biologic
systems are essentially isothermic and use
chemical energy to power living processes.
• Animal obtains suitable fuel from its food to
provide the energy for metabolism.

•

Death

starvation.
Bio medical importance
• Thyroid hormones control the rate of energy
release and disease results when they
malfunction.
• Excess storage of surplus energy causes
obesity.
Energy Production Through the
Krebs's Cycle

• This cycle is a series of chemical intermediates.
• Each step is catalyzed by a specific enzyme.
Energy Production Through the
Krebs's Cycle
• The cycle starts with oxaloacetate and ends with
oxaloacetate.

• The cycle produces 1 ATP, 3 NADH, and 1
FADH2 per turn.
Thank you

Questions are welcomed

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