There are several key land use challenges in Africa including increased agricultural land decreasing forest cover, sharply increased degraded lands, and competition for land resources. Research is needed to manage tradeoffs between food and cash crops, improve food production while preserving the environment, and clarify land planning decisions in the context of decentralization. Harmonizing land use monitoring and establishing an ecosystem land use information base can help mainstream information to support decision making across scales. Research must connect the spaces of productive land use systems and sustainability to have impact on the main challenges of Future Earth.