Lymphogranuloma venereum is caused by Chlamydia trachomatis and has an incubation period of 3-30 days, presenting initially with a painless ulcer and swollen inguinal nodes. Complications include vulval elephantiasis and rectal stricture, while diagnosis is made through culture and isolation. Treatment options include doxycycline or azithromycin over a specified duration.

1. Lymphogranuloma Venereum
Dr. Yashika

2. • Causative agent : Chlamydia trachomatis
• Incubation period: 3-30 days

3. Clinical features :
Initial phase:
• Painless papule, pustule or ulcer in vulva, urethra,
rectum or cervix.
• Involved inguinal nodes feels rubbery.
• Acute lumphangitis and lymphadenitis.
• Necrosed glands and abscess formation.
• Rupture of abscess occurs within 7-15 days.
• Sinus and fistula formation.
• Intense fibrosis with lymphatic drainage.

4. Secondary phase : Painful adenopathy.
Classical clinical sign:
• Groove sign
A depression between the groups of inflammed nodes.

5. Complication:
• Vulval elephantiasis
• Perineal scarring
• Rectal stricture
• Sinus and fistula formation.

6. Diagnosis
• Culture and isolation
• Detection of LGV

7. Treatment:
Doxycycline 100 mg BID x 21days.
Azithromycin 1 gm PO weekly x 3 weeks
Abscess aspiration