This presentation is all about the Lymphogranuloma

1. LYMPHOGRANULOMA VENEREUM
Chlamydia Trachomatis
Trachomatis is an obligate intracellular parasite
that lack a cell Serotypes D to K are associated
with non-gonococcal urethritis, cervicitis and
PID,
while Serotypes, L1, L2, L3 anre associated with
lymphogranuloma venereum.

2. MODES OF TRANSMISSION
Transmission is primarily through sexual contact.
CLINICAL FINDINGS
a. Urogenital tract infection
-Most are asymptomatic.If symptomatic it manifest
cervicitis endometritis urethritis salpingitis
bartholinitis perihepatitis, andmucopurulent
discharge.

3. b.Lymphogranuloma venereum
-A primary lesion appears at the site plof
infection.The lesion is either a papule or ulcer,
which is small, painless and rapidly. The second
stage is
manifested by enlarged lymph nodes that are
painful(called buboes) and ruptures forming
draining fistulas

4. Enlarged painful lymph nodes (buboes) that
rupture and chain with pus (arrow) are
characteristics of LGV by Chlamydia
Trachomatis.

5. LABORATORY DIAGNOSIS
1.Giemsa-stained cell scrapings
2.Culture most specific diagnostic method
TREATMENT AND PREVENTION
Azithromycin or doxycycline or
erythromycin
CHANCROID
HAEMOPHILUS DUCREYI
The etiologic agent is a Grain-negative coccobacillus unlike H
influenza,
it requires only the factor growth,but not the V factor.

6. MODES OF TRANSMISSION
Chancroid is transmitted through sexual contact
LABORATORY DIAGNOSIS
Microscopy and culture
TREATMENT AND PREVENTION
Antibiotics like Cephalosporins or azithromycin
GENITAL HERPES
-HERPES SIMPLEX VIRUS
The etiologic agent is a DNA virus under the family of human
Herpesviruses.There are two types of HSV (HVS-1 and HSV-
2).The virus is capable of latency in the neurons hence recurrent infections
occurs.

7. -MODES OF TRANSMISSION
The man mode of transmission is through sexual contact.
-CLINICAL FINDINGS
Genital herpes is caused by both HSV types 1&2, but majority of
cases are caused by types 2.Most primary infections are
symptomatic.The lesion are vesicular, which later on ruptures,
resulting in ulcer, and are painful with inguinal
lymphadenopathy.The lesion are seen in the vulva,vagina, cervix
or
perianal area and are accompanied by pruritus and mucoid
vaginal discharge.

8. Characteristics lesions in
chandroid.

9. LABORATORY DIAGNOSIS
Tzanck smear to demonstrate the characteristics inclusion
bodies known as
low dry types A inclusion.
TREATMENT AND PREVENTION
The drug choices is acyclovir, but itdoes not prevent recurrences
the
prevention is the same as the othersexually transmitted
diseases.

10. (a) Herpes genitalis due to herpes simplex
virus types 2 and genital warts (b)
Condyloma acuminate caused by human
papilloma virus

11. NDYLOMATA ACUMINATA
UMAN PAPILLOMA VIRUS
e etiologic agent is a DNA virus under the family of
povaviruses .HPV is capable of immortalizing or
nsforming infected cell, leading to malignancy.
ODES OF TRANSMISSION
ual contact
INICAL FINDINGS
nital warts (or condylomata acuminata) occur most
commonly in the genital or perianal areas.

12. ACQUIRED IMMUNODEFICIENCY SYNDROME
(AIDS)
Human Immunodeficiency Virus (HIV), its
mechanism
of infection (integrate its RNA genome into the host
cell's DNA), and its interaction with
CD4+ T cells via glycoproteins gp120 and gp41

13. MODES OF TRANSMISSION
Several transmission routes, including sexual contact,
sharing needles, perinatal transmission (from mother to
child), and blood transfusions. High-risk groups
mentioned include sexually active individuals,
intravenous drug users, homosexuals, and overseas
contract workers

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