Mesh analysis is a technique for analyzing electrical circuits using loops or meshes. It involves assigning a mesh current to each loop and writing Kirchhoff's voltage law equations for each mesh. The mesh equations take the form of a matrix equation that can be solved for the unknown mesh currents. Key aspects of mesh analysis include defining mesh currents, writing KVL equations clockwise around each mesh, identifying common resistance terms between meshes, and handling circuits with current sources by removing the source and including it as a constraint.