A gastrografin enema is an x-ray examination of the colon and rectum where a water-soluble contrast agent called gastrografin is used to fill the bowels. During the procedure, which takes about 25 minutes, a soft tube is inserted and gastrografin is injected while x-rays are taken to assess for any leaks outside the bowel. The contrast agent is then drained out and the patient can use the restroom. Possible discomfort from tube insertion may occur but is usually minor. Results are analyzed by a radiologist and reported to the requesting doctor.