1. Three major West African kingdoms dominated the region from around 300 CE to 1600 CE. Ghana rose first through the gold-salt trade with North Africa, but declined after attacks in the 11th century. 2. Mali then grew to become the largest of the three kingdoms under Mansa Musa's rule in the 14th century. His pilgrimage to Mecca demonstrated Mali's vast wealth. However, internal divisions later weakened Mali. 3. The Songhai Empire subsequently controlled the region from the 1400s-1500s through strong leadership and naval power on the Niger River. But it fell in 1591 when its army was defeated by Moroccan forces using advanced gunpow