1) RNAi is a mechanism for gene silencing that has been used to improve the nutritional value of crops. It works by degrading mRNA or inhibiting translation through small RNA molecules like siRNAs and miRNAs. 2) Examples of nutritional improvements include producing gluten-free rice, increasing grain amylose content in wheat, and enhancing beta-carotene levels in potato. RNAi has also been used to reduce anti-nutritional compounds like caffeine in coffee and BOAA in Lathyrus sativus. 3) Going forward, RNAi can help address malnutrition by facilitating production of crops with customized nutritional profiles, vaccines delivered through plants, and other advances to improve global food security.