The document provides updates on infectious diseases from Clostridium difficile infection to new vaccines and antimicrobial agents. It discusses the increasing severity and prevalence of C. difficile, new diagnostic tests and treatment options including fidaxomicin and stool transplants. New antimicrobial agents for gram-positive infections like daptomycin, linezolid and ceftaroline are mentioned. Vaccine recommendations are updated for herpes zoster, pertussis and pneumococcus.