Otic preparations are pharmaceutical products used to treat conditions of the external and inner ear. They are applied inside, outside, or around the ear to exert therapeutic effects. Common conditions treated include bacterial infections, ear wax impaction, swimmer's ear, and skin disorders of the ear. Otic preparations contain various active ingredients like antibiotics, solvents, corticosteroids, and analgesics depending on the specific condition being treated.

1. OTIC PREPARATIONS
COMPOUNDING & MANUFACTURING
II
Presentation of
Luisabel Novelo

2. Otic Preparation
• From Greek ōtikos;
• Of, relating to, or located near the ear;
auricular.
• Otic preparations are pharmaceutical products
(drugs) that are used inside, outsides, or
around the ears to exert therapeutic effect.
• In general, otic preparation are products
applied to or in the ear to treat conditions of
the external and middle ear.

3. Ear Physiology
• The auricle is the opening to the ear;
• The ear lobe surrounds the auricle;
• The external auditory canal starts at the
auricle and ends at the tympanic membrane

4. Ear Wax
• The waxy material of the ear is called
cerumen, or commonly known as ear wax.
• Cerumen is formed from the combination of
the oily secretions from the exocrine glands
with fatty fluid from the apocrine glands in the
external auditory canal.

5. • Cerumen contains lysosomes, and enzyme
that inhibits bacterial growth.
• The cerumen helps in the
lubrication of the ear canal.
• Cerumen traps dust and other
materials from reaching the inner ear.
• Cerumen can also decreasing auditory sounds,
thus requiring removal.

6. Otic Preparations
• Otic preparations are used to treat conditions
of the external and inner ear.
• Bacterial growth in the external auditory canal
are treated with solvents containing glycerine,
vegetable oils, mineral oil, and PEG 300.
• Antibiotics are also used in
combination with other
solvents.

7. • Ear wax impaction of the external auditory
canal is usually treated with solvents
containing carbamide peroxide, glycerin,
hydrogen peroxide, and olive oil.

8. • Swimmer’s ear is a condition whereby water
has become trapped between the cerumen
impaction and the tympanic membrane.
• Treatment involves isopropyl alcohol, glycerin,
boric acid, hydrocortisone, ethyl alcohol,
acetic acid, and aminoglycosides antibiotics.

9. • Skin disorders of the ear are usually treated
with a variety of dermatological preparations.
• Contact dermatitis is treated with 2.5%
aluminum acetate.
• Itching of the ear can be treated using topical
hydrocortisone, triamcinolone, or
dexamethasone.
• Otic ointments are usually best for skin
conditions of the ear.
• Analgesic are used for ear pain while other
treatments target underlying conditions.

10. Using Ear Drops
• Before using ear drops to treat conditions of
the ear patient should be reminded of the
purpose of the preparation, the duration of
administration, and prevention techniques to
avoid recurrence.