The circulatory system, also known as the cardiovascular system, is made up of the heart and blood vessels. It is responsible for transporting blood, nutrients, oxygen, water, and waste products throughout the entire body in mammals. The heart pumps around 1.5 gallons of blood per minute through a network of arteries, veins, and capillaries, ensuring all cells receive nutrients and oxygen and remove waste. Blockages in the coronary arteries, which supply the heart, can lead to coronary heart disease over many years as plaque builds up in the arteries.