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Transaortic aortic valve
implantation with Sapien
     Gian Luca Martinelli MD
           CV Surgery Dept.
   S Anna Hospital – Catanzaro - Italy
VASCULAR ACCESS
                         Transsubclavian



Transaortic
                              Transapical




               Transfemoral
TF-
TF-AVI SURGICAL EXPOSURE
TA - AVI
ALTERNATIVE APPROACHES

• Transsubclavian (generally left)
• Transaortic: two options


Minimal anterior thoracotomy   Upper ministernotomy
CLINICAL PRESENTATION
81 yo female
NYHA III
Good EF, severe aortic stenosis
Chronic pulmonary disease in medical
  treatment, cerebral and peripherical vascular
  disease
LogisticEuroScore 28%, EuroScore II 6%, STS
  score 7%
ECHOCARDIOGRAM

EF 45%, functional area 0,75 cm2, mean
gradient 40 mmhg, peak velocity > 4 m/sec
ECHOCARDIOGRAM
MSCT SCAN
CHOICE OF MINISTERNOTOMY
Conventional approach, TF-
  AVI or TA-AVI, was not
  desirable AND the
  ascending aorta was
  deemed suitable for
  conventional cannulation
STEP BY STEP PROCEDURE
A 5 cm J-shaped upper ministernotomy;
A 8-Fr sheath insertion through a double
   pledgets reinforced purse string
   sutures with the Seldinger technique;
Crossing aortic valve with a straight wire
   supported by a right Judkins catheter;
Insertion of a pre-shaping super stiff
   guide wire in left ventricle;
Finally the Ascendra 2 transapical
   delivery system is introduced through
   the aorta and kept in its upper part.
IDEAL STAIGHT LINE FOR OPTIMAL
           VALVE RELEASE
• A non-calcified area on the
  ascending aorta was identified
  which would allow direction of
  the sheath in a STRAIGHT
  LINE to deploy the device,
  leaving enough space
  between the Ascendra system
  and the device itself.
BALOON AORTIC
VALVULOPLASTY
VALVE RELEASE
AORTIC ANGIOGRAM AND
ECHOCARDIOGRAM CONTROL
THE DAY AFTER

       • RX TORACE
LESSON LEARNED
• Procedural success: adequate technical placement,
  normal bioproshesis performance and recovery;
• Advantage: overcoming challenging aorto-ileo –
  femoral-vascular disease, avoid arch crossing and
  new left ventricular scar;
• The proximity between the puncture site and the
  native aortic valve allows easier manipulation and
  delivery of the device, with an IDEAL straight line.
CONCLUSIONS
• Upper ministernotomy represent an additional option
  for patients who are NOT candidates for TF-AVI and in
  whom an apical approach may represent a less
  desirable option (low EF, severe pulmonary
  disfunction);
• Access to arterial brachiocephalic trunk is also avaible
  through this incision;
• Controindication for transaortic TAo-AVI approach:
  porcelain aorta.

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Trans aortic tavi

  • 1. Transaortic aortic valve implantation with Sapien Gian Luca Martinelli MD CV Surgery Dept. S Anna Hospital – Catanzaro - Italy
  • 2. VASCULAR ACCESS Transsubclavian Transaortic Transapical Transfemoral
  • 4.
  • 6. ALTERNATIVE APPROACHES • Transsubclavian (generally left) • Transaortic: two options Minimal anterior thoracotomy Upper ministernotomy
  • 7. CLINICAL PRESENTATION 81 yo female NYHA III Good EF, severe aortic stenosis Chronic pulmonary disease in medical treatment, cerebral and peripherical vascular disease LogisticEuroScore 28%, EuroScore II 6%, STS score 7%
  • 8. ECHOCARDIOGRAM EF 45%, functional area 0,75 cm2, mean gradient 40 mmhg, peak velocity > 4 m/sec
  • 11. CHOICE OF MINISTERNOTOMY Conventional approach, TF- AVI or TA-AVI, was not desirable AND the ascending aorta was deemed suitable for conventional cannulation
  • 12. STEP BY STEP PROCEDURE A 5 cm J-shaped upper ministernotomy; A 8-Fr sheath insertion through a double pledgets reinforced purse string sutures with the Seldinger technique; Crossing aortic valve with a straight wire supported by a right Judkins catheter; Insertion of a pre-shaping super stiff guide wire in left ventricle; Finally the Ascendra 2 transapical delivery system is introduced through the aorta and kept in its upper part.
  • 13. IDEAL STAIGHT LINE FOR OPTIMAL VALVE RELEASE • A non-calcified area on the ascending aorta was identified which would allow direction of the sheath in a STRAIGHT LINE to deploy the device, leaving enough space between the Ascendra system and the device itself.
  • 17. THE DAY AFTER • RX TORACE
  • 18. LESSON LEARNED • Procedural success: adequate technical placement, normal bioproshesis performance and recovery; • Advantage: overcoming challenging aorto-ileo – femoral-vascular disease, avoid arch crossing and new left ventricular scar; • The proximity between the puncture site and the native aortic valve allows easier manipulation and delivery of the device, with an IDEAL straight line.
  • 19. CONCLUSIONS • Upper ministernotomy represent an additional option for patients who are NOT candidates for TF-AVI and in whom an apical approach may represent a less desirable option (low EF, severe pulmonary disfunction); • Access to arterial brachiocephalic trunk is also avaible through this incision; • Controindication for transaortic TAo-AVI approach: porcelain aorta.