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PHARMACOLOGY AND
TOXICOLOGICAL SCREENING
METHODS
Presentation on: TOXICOLOGY AND TYPES
UNDER GUIDANCE BY : DONE BY:
Dr.E.TAMILJOTHI G.SADHANA
Professor 1st M.Pharm
DEPARTMENT OF PHARMACOLOGY DEPARTMENT OF PHARMACOLOGY
Arulmigu kalasalingam college of pharmacy
TOXICOLOGY:
Toxicology is the scientific study of adverse effects that occur in living
organisms due to chemicals.
TYPES OF TOXICOLOGY
● Analytical toxicology
● Applied toxicology
● Clinical toxicology
● Veterinary toxicology
● Forensic toxicology
● Environment toxicology
● Industrial toxicology
ANALYTICAL TOXICOLOGY:
It is the branch of toxicology which deals with the study of detection
And assay of poisonous chemicals including their metabolites that
Could affect the biological system.
APPLIED TOXICOLOGY:
It is the absorption of new and modern methods (or) technologies
For early detection of toxicants in the field of setting (or) practice
Area.
CLINICAL TOXICOLOGY
It is mainly involved in the study of diagnosis &
Treatment of poisoning that can occur in humans
FORENSIC TOXICOLOGY
It is use of toxicology & discipline such as analytical
Chemistry, pharmacology & clinical Chemistry to
Aid medical or legal investigation of death,poisoning
And drug.
ENVIRONMENTAL TOXICOLOGY
It is the branch of toxicology in which study of presence of
Different toxicants including metabolites and degradation
Products in environment & effects on humans & animals.
INDUSTRIAL TOXICOLOGY
It is the study of harmful effects of chemicals, biological
agents/ physical agents encountered in workplace.
VETERINARY TOXICOLOGY
Veterinary toxicology focus in the study
Of diagnosis and treatment of animal
Poisoning including the transmission of
Toxin from animals to humans via (milk,meat,fish,food stuff)
GENERAL TOXICOLOGY
GENERAL TOXICOLOGY
General toxicology studies explore potential of chemical to cause adverse health effects
After single or repeated exposure.
MECHANISTIC TOXICOLOGY
● Mechanistic toxicology is the study of chemicals (or) physical agents
Interact with living organisms to cause toxicity.
● Aim of mechanistic toxicology is to identify that xenobiotics enter
An organism and how these are distributed metabolize in the body.
Mechanism of toxicity of substance enhances the ability to prevent toxicity and design more desirable chemical
Example: organophosphate pesticides inhibit ACE
REGULATORY TOXICOLOGY
Regulatory toxicology is the branch of toxicology
(Study of adverse effects of chemicals) that uses
Scientific knowledge to develop regulations and
Other strategies for reducing and controlling exposure
To dangerous chemicals.
Example:
● Food and drug administration (FDA)
● Environmental protection agency(EPA)
● Occupational safety & health administration (OSHA)
DESCRIPTIVE TOXICOLOGY
Descriptive toxicology is concerned directly with
Toxicity testing,which provides information for
Safety evaluation and regulatory requirements.
● Hazard identification
● Dose response assessment
● Exposure assessment
● Risk characterization
Thank you

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TOXICOLOGY AND ITS TYPES

  • 1. PHARMACOLOGY AND TOXICOLOGICAL SCREENING METHODS Presentation on: TOXICOLOGY AND TYPES UNDER GUIDANCE BY : DONE BY: Dr.E.TAMILJOTHI G.SADHANA Professor 1st M.Pharm DEPARTMENT OF PHARMACOLOGY DEPARTMENT OF PHARMACOLOGY Arulmigu kalasalingam college of pharmacy
  • 2. TOXICOLOGY: Toxicology is the scientific study of adverse effects that occur in living organisms due to chemicals. TYPES OF TOXICOLOGY ● Analytical toxicology ● Applied toxicology ● Clinical toxicology ● Veterinary toxicology ● Forensic toxicology ● Environment toxicology ● Industrial toxicology
  • 3. ANALYTICAL TOXICOLOGY: It is the branch of toxicology which deals with the study of detection And assay of poisonous chemicals including their metabolites that Could affect the biological system. APPLIED TOXICOLOGY: It is the absorption of new and modern methods (or) technologies For early detection of toxicants in the field of setting (or) practice Area.
  • 4. CLINICAL TOXICOLOGY It is mainly involved in the study of diagnosis & Treatment of poisoning that can occur in humans FORENSIC TOXICOLOGY It is use of toxicology & discipline such as analytical Chemistry, pharmacology & clinical Chemistry to Aid medical or legal investigation of death,poisoning And drug.
  • 5. ENVIRONMENTAL TOXICOLOGY It is the branch of toxicology in which study of presence of Different toxicants including metabolites and degradation Products in environment & effects on humans & animals. INDUSTRIAL TOXICOLOGY It is the study of harmful effects of chemicals, biological agents/ physical agents encountered in workplace.
  • 6. VETERINARY TOXICOLOGY Veterinary toxicology focus in the study Of diagnosis and treatment of animal Poisoning including the transmission of Toxin from animals to humans via (milk,meat,fish,food stuff) GENERAL TOXICOLOGY
  • 7. GENERAL TOXICOLOGY General toxicology studies explore potential of chemical to cause adverse health effects After single or repeated exposure. MECHANISTIC TOXICOLOGY ● Mechanistic toxicology is the study of chemicals (or) physical agents Interact with living organisms to cause toxicity. ● Aim of mechanistic toxicology is to identify that xenobiotics enter An organism and how these are distributed metabolize in the body. Mechanism of toxicity of substance enhances the ability to prevent toxicity and design more desirable chemical Example: organophosphate pesticides inhibit ACE
  • 8. REGULATORY TOXICOLOGY Regulatory toxicology is the branch of toxicology (Study of adverse effects of chemicals) that uses Scientific knowledge to develop regulations and Other strategies for reducing and controlling exposure To dangerous chemicals. Example: ● Food and drug administration (FDA) ● Environmental protection agency(EPA) ● Occupational safety & health administration (OSHA)
  • 9. DESCRIPTIVE TOXICOLOGY Descriptive toxicology is concerned directly with Toxicity testing,which provides information for Safety evaluation and regulatory requirements. ● Hazard identification ● Dose response assessment ● Exposure assessment ● Risk characterization