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Dr.Medhat Ibrahim. MD.
A 3- years-old child with : 
-A mass on right side of neck. 
-Swelling first noticed by mother when child 
was 7 months old. 
The infant is eating well, 
thriving, and otherwise healthy
A 4-mm cystic mass noted along the anterior 
border of the left sternocleidomastoid muscle. 
Mass is not red or tender, and is freely movable 
beneath the skin.
A branchial cleft cyst results from persistence 
of the cervical sinus of His
Branchial cleft anomalies may present as : 
a cyst, 80% 
sinus, 
fistula, 
cartilaginous remnant. 
Approximately 80% of branchial cleft anomalies 
present as a cyst. 
About 95% are formed from the region of the 
second branchial arch. 
The remaining 5% arise from the regions of the 
first, third, or fourth arches.1,5
A branchial cleft cyst typically presents: 
As a painless, 
Mobile, 
Fluctuant mass. 
Located along the anterior border of the 
sternocleidomastoid muscle, 
Usually just above the clavicle. 
Approximately 97% to 98% of the lesions are 
unilateral, 
83% to 97% are on the left side--presumably 
consequent to asymmetrical vascular 
development.
Although branchial cleft cysts are congenital 
and might be noted at birth, 
most are not detected until the first or second 
decade of life. 
Some are detected when they become more 
prominent in late childhood. 
Other cases become apparent during inter 
current upper respiratory tract infections or 
when the cyst becomes infected!!!
The diagnosis is established by physical examination. 
Ultrasonography can help delineate the cystic nature 
of the lesion if the diagnosis is in doubt. 
The differential diagnosis includes : 
 Cervical lymphadenopathy, 
 Fibrous dysplasia of the sternocleidomastoid muscle 
(fibromatosis coli), 
 Dermoid cyst, 
 Cystic hygroma. 
 A thyroglossal duct cyst is a midline structure, and should be 
easily differentiated
Secondary bacterial infection is a possible 
complication. 
Change to fistulae 
Squamous cell carcinoma is reported in 
adulthood
A branchial cleft cyst is lined by: 
Squamous 
Columnar epithelium. 
The cyst usually contains either 
 Clear fluid 
 Toothpaste-like material 
 Cholesterol crystals. 
So it is tubulo dermoid 
What is other tubulo- dermoid structures?
Cyst, and other remnants: 
 Complete surgical excision with careful attention to 
identifying deeper components is the treatment of choice. 
 Aspiration, or incision and drainage, is associated with 
an increased risk of recurrence and of such complications 
as wound infection or hemorrhage. 
 Secondary infection requires systemic antibiotic therapy 
Fistula 
 Complete surgical excision with careful attention to identifying 
deeper components is the treatment of choice.
Opening of the fistula 
At anterior boarder of sternoclidoastid 
Just above the clavicle 
Saliva come out though the opening
Methylen blue injection: 
Multiple channels 
Remnant from the original infected cyst
Micro channels 
Main fistula
Anterior boarder of the 
sterno-mastid 
The fistula hooking around it 
The micro-channels become 
fine
Deep structure 
The fistula go deep 
to the 
sternomastoid, 
It become one 
channel 
Passing between 
the internal and 
external carotid 
artery 
Just behind the 
superior thyroid 
artery and nerve 
accompanied
Thyroglosal fistula
Thyroglosal fistula

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Thyroglosal fistula

  • 2. A 3- years-old child with : -A mass on right side of neck. -Swelling first noticed by mother when child was 7 months old. The infant is eating well, thriving, and otherwise healthy
  • 3. A 4-mm cystic mass noted along the anterior border of the left sternocleidomastoid muscle. Mass is not red or tender, and is freely movable beneath the skin.
  • 4. A branchial cleft cyst results from persistence of the cervical sinus of His
  • 5.
  • 6. Branchial cleft anomalies may present as : a cyst, 80% sinus, fistula, cartilaginous remnant. Approximately 80% of branchial cleft anomalies present as a cyst. About 95% are formed from the region of the second branchial arch. The remaining 5% arise from the regions of the first, third, or fourth arches.1,5
  • 7. A branchial cleft cyst typically presents: As a painless, Mobile, Fluctuant mass. Located along the anterior border of the sternocleidomastoid muscle, Usually just above the clavicle. Approximately 97% to 98% of the lesions are unilateral, 83% to 97% are on the left side--presumably consequent to asymmetrical vascular development.
  • 8. Although branchial cleft cysts are congenital and might be noted at birth, most are not detected until the first or second decade of life. Some are detected when they become more prominent in late childhood. Other cases become apparent during inter current upper respiratory tract infections or when the cyst becomes infected!!!
  • 9. The diagnosis is established by physical examination. Ultrasonography can help delineate the cystic nature of the lesion if the diagnosis is in doubt. The differential diagnosis includes :  Cervical lymphadenopathy,  Fibrous dysplasia of the sternocleidomastoid muscle (fibromatosis coli),  Dermoid cyst,  Cystic hygroma.  A thyroglossal duct cyst is a midline structure, and should be easily differentiated
  • 10. Secondary bacterial infection is a possible complication. Change to fistulae Squamous cell carcinoma is reported in adulthood
  • 11. A branchial cleft cyst is lined by: Squamous Columnar epithelium. The cyst usually contains either  Clear fluid  Toothpaste-like material  Cholesterol crystals. So it is tubulo dermoid What is other tubulo- dermoid structures?
  • 12. Cyst, and other remnants:  Complete surgical excision with careful attention to identifying deeper components is the treatment of choice.  Aspiration, or incision and drainage, is associated with an increased risk of recurrence and of such complications as wound infection or hemorrhage.  Secondary infection requires systemic antibiotic therapy Fistula  Complete surgical excision with careful attention to identifying deeper components is the treatment of choice.
  • 13. Opening of the fistula At anterior boarder of sternoclidoastid Just above the clavicle Saliva come out though the opening
  • 14. Methylen blue injection: Multiple channels Remnant from the original infected cyst
  • 16.
  • 17. Anterior boarder of the sterno-mastid The fistula hooking around it The micro-channels become fine
  • 18. Deep structure The fistula go deep to the sternomastoid, It become one channel Passing between the internal and external carotid artery Just behind the superior thyroid artery and nerve accompanied