This document discusses various techniques for reconstructing soft tissue defects of the thumb. It begins with an overview of thumb anatomy and blood supply. Various local flap options are then described for small to moderate sized defects, including V-Y flaps, Moberg flaps, cross-finger flaps, and digital perforator flaps based on the radial or ulnar palmar arteries. Larger defects may be covered with pedicled flaps such as neurovascular island flaps or first dorsal metacarpal artery flaps. The document concludes by describing free flaps for thumb reconstruction, such as bipedicle flaps from the index finger or chimeric flaps based on the groin vasculature.
The objective in the management of soft-tissue injuries of the hand is to achieve primary wound healing.
The choice of treatment of fingertip is based on the
mechanism of injury ,
the size of the defect,
location and status of the wound
injuries to other parts of the hand
other factors(patient’s age, sex, general health, and occupation)
Compiled by Dr S Selvaganesh
Hand Surgery Fellow KTPH
Triceps to axillary nerve transfer is used in partial plexus injuries where the C5/6 component is damaged and the C7/8 and T1 are intact. The typical indication is in the C5 or C5/6 avulsion injury but it may also be used in cases of C5/6 rupture where presentation is delayed, grafting of the upper trunk has not been successful or in continuity lesions of the upper trunk that failed to reinnervate. It may also be used to salvage the axillary nerve rupture at the quadrilateral space associated with high energy shoulder dislocation or the rare non-recovering isolated lesion in continuity of the axillary nerve following a low energy shoulder dislocation.
The objective in the management of soft-tissue injuries of the hand is to achieve primary wound healing.
The choice of treatment of fingertip is based on the
mechanism of injury ,
the size of the defect,
location and status of the wound
injuries to other parts of the hand
other factors(patient’s age, sex, general health, and occupation)
Compiled by Dr S Selvaganesh
Hand Surgery Fellow KTPH
Triceps to axillary nerve transfer is used in partial plexus injuries where the C5/6 component is damaged and the C7/8 and T1 are intact. The typical indication is in the C5 or C5/6 avulsion injury but it may also be used in cases of C5/6 rupture where presentation is delayed, grafting of the upper trunk has not been successful or in continuity lesions of the upper trunk that failed to reinnervate. It may also be used to salvage the axillary nerve rupture at the quadrilateral space associated with high energy shoulder dislocation or the rare non-recovering isolated lesion in continuity of the axillary nerve following a low energy shoulder dislocation.
ACKNOWLEDGE PUBLICATION - IJSCR ACKNOWLEDGEMENT - Dr. RAHUL VC TIWARI, SIBAR INSTITUTE OF DENTAL SCIENCES, GUNTUR, ANDHRA PRADESH, INDIA. PUBLISHED LITERATURE
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
6. Blood supply of thumb
SPA: superficial palmar arch
DPA: deep palmar arch
UA: ulnar artery
RA: radial artery
UPDAT: ulnopalmar digital
artery of the thumb
UDDAT: ulnodorsal digital
artery of the thumb
RPDAT: radiopalmar digital
artery of the thumb
RDDAT: radiodorsal
digital artery of the thumb
FPMA: first palmar
metacarpal artery
FDMA: first dorsal
metacarpal artery
SPBRA: superficial palmar
branch of radial arteryArterial Supply of the Thumb – Systemic Review
Miletin J, Sukop A, Baca V, Kachlik D
doi: 10.1002/ca.22973
7. Blood supply of thumb
Arterial Supply of the Thumb – Systemic Review
Miletin J, Sukop A, Baca V, Kachlik D
doi: 10.1002/ca.22973
8. Blood supply of thumb
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
Branches, distributions and anastomosis
of right thumb dorsal artery.
(a) Radial view, (b) Dorsal view.
1. Radial palmar thumb
artery
2. ulnar palmar thumb artery,
3. thumb dorsal artery,
4. dorsal perforator,
5. tendon of extensor pollicis longus,
6. tendon of extensor pollicis brevis,
7. tendon of abductor pollicis longus,
8. cutaneous nerve of radial dorsal thumb
9. Thumb softissue defects
• Amputations
• Dorsal defects
• Palmar tip defects
• Glove injury
• Absence of thumb = 40% disability of hand as a whole
http://www.wheelessonline.com/ortho/management_of_thumb_soft_tissue_defects_amputations
10. Full-thickness skin grap
• Defects up to 1.5 cm in diameter with no bone exposure can
be effectively treated with dressing changes. Daily dressing
changes with petroleum or bismuth-impregnated gauze are
relatively easy for patients.
• Defects > 1,5 cm with a stable base, however, require skin grafting.
Full-thickness grafts are usually preferred, as they are more durable
and stable, especially in the contact areas subject to pressure and
shear. Small full-thickness skin grafts can be harvested from the
hypothenar eminence or the volar wrist crease. Larger skin grafts,
however, are best harvested from the upper inner arm or groin
crease.
11. V-Y flap, Moberg flap
• When phalangeal
bone is exposed
at the thumb tip
• This flap can
easily cover a
defect of 1–2 cm2
CHAPTER 13 • Thumb reconstruction: Non-microsurgical techniques
Plastic Surgery - Hand and Upper Extremity - Volume Six- Edition 4th
Chang J
12. Moberg flap
a Intraoperative picture of thumb-tip amputation
with Moberg advancement flap (MAF) elevation
in progress.
b Flexed thumb IP joint with MAF inset to cover
thumb-tip amputation.
cThumb appearance at 3 months with early
healing.
d Thumb appearance at 3 weeks showing
maintained first web space.
e Full IP joint extension 4 months following MAF
coverage.
f Satisfactory IP joint flexion 4 months following
MAF coverage
https://musculoskeletalkey.com/reconstruction-of-the-thumb-tip/
13. Cross-finger flap
• The cross-fnger flap from the index
fnger is an excellent
reconstructive technique for larger
volar and tip defects of the thumb,
up to 2–3 cm2
• A full-thickness skin graft is then
sutured to the dorsum of the index
fnger. A bulky thumb splint is
applied.
• At 2 or 3 weeks, the flap is divided
and the inset to the thumb is
completed After division,
aggressive
range-of-motion therapy for both
the thumb and index fnger should
begin.CHAPTER 13 • Thumb reconstruction: Non-microsurgical techniques
Plastic Surgery - Hand and Upper Extremity - Volume Six- Edition 4th
Chang J
14. Cross-finger flap
CHAPTER 13 • Thumb reconstruction: Non-microsurgical techniques
Plastic Surgery - Hand and Upper Extremity - Volume Six- Edition 4th
Chang J
15. Digital dorsal perforator flap
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
16. Thumb radialis palmar artery perforator flap
Detect and select the appropriate perforators at proximal
end of thumb metacarpophalangeal joint of the hand and radial
edge using Doppler ultrasound, expose the vessels and nerve tract
on the radial thumb, and then further identify the radial palmar
artery perforator. Skin graft in full-thickness from inner forearm to
repair the donor site by free transplantation.
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
17. Thumb radialis palmar artery perforator flap
Displaced thumb radialis palmar artery perforator flap in
repairing defects of thumb pulp skin and soft tissues
(surgical photos provided by Xiao Zhou). (a) Defect
wound, (b) design of the flap, (c) flap dissociation and
vessel pedicle exposure, (d) repair fnished, (e) thumb
appearance 2 months after operation, (f) thumb function
2 months after operation
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
18. Thumb radialis palmar artery perforator flap
Displaced thumb radialis palmar
artery dorsal perforator flap in
repairing defects of the skin and
soft tissue on thumb pulp (surgical
photos provided by Zengbing Xia).
(a) Soft tissue defect and flap design
(b) exposure of dorsal vessel branch
(c) resection of the flap
(d) after flap transposition surgery
(e) appearance of donor site 5 days
after operation
(f) appearance of flap 5 days after
operation
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and
Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
19. Thumb ulnar palmar artery perforator flap
Displaced thumb ulnar palmar artery perforator
flap in
repairing thumb nail bed defect (surgical photos
provided by Xiao Zhou).
(a) Defect of left thumb nail bed and flap design,
(b) Flap dissection and vessel pedicle exposure,
(c) Repair fnished,
(d) Flap appearance 6 months after operation
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
20. Thumb ulnar palmar artery perforator flap
Displaced dorsal thumb ulnar palmar artery perforator
flap for repairing defect wound of thumb tip (surgical
photos provided by Zengbing Xia).
(a) Right thumb tip defect accompanied by bone exposure,
(b) Design of flap
(c) Vessel exposure
(d) Resection of flap
(e) Appearance 16 days after flap transposition surgery
(f) Conditions of donor site and recipient area 16 days
after operation
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction and
Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
21. Thumb ulnar palmar artery perforator flap
Displaced dorsal thumb ulnar palmar artery
flap for repairing thumb pulp defect
(surgical photos provided by Jian Lin).
(a) Defect of left thumb pulp
(b) Design of the flap
(c) Flap resection and vessel pedicle
exposure
(d) Flap survived completely 10 days after
operation
Atlas of Perforator Flap and Wound Healing_ Microsurgical Reconstruction
and Cases-Springer Singapore (2019)
He-Ping Zheng, Jian Lin, Yong-Qing Xu, De-Qing Hu
22. Neurovascular island flap
• It is rarely used as a primary
coverage flap, although it is
certainly possible to use it in that
manner. Rather, its most
common use is for the
restoration of sensation to the
thumb pulp following
reconstruction.
• The flap is based on the ulnar
neurovascular bundle of either
the middle or ring fnger. The
ulnar side
of the digit is chosen because its
loss will have minimal effect on
grip and pinch activities.CHAPTER 13 • Thumb reconstruction: Non-microsurgical techniques
Plastic Surgery - Hand and Upper Extremity - Volume Six- Edition 4th
Chang J
23. First dorsal metacarpal artery flap
Sensate First Dorsal Metacarpal Artery Flap for Resurfacing Extensive Pulp Defects of the Thumb
Shun-Cheng Chang, MD, Shao-Liang Chen, MD, Tim-Mo Chen, MD, Chia-Jueng Chuang, MD, Tian-Yeu Cheng, MD, and Hsian-Jenn Wang, MD
DOI https://doi.org/10.1055/s-0038-1675369
• The artery runs over the fascial layer of
the first dorsal interosseous muscle and
divides into the radial branch to the
thumb, the intermediate branch to the
first web space, and the ulnar branch to
the index finger
• The ulnar branch usually courses distally
within the musculo-osseous groove,
between the ulnar head of the first
dorsal interosseous muscle and the radial
shaft of the second metacarpal bone,
until it reaches the metacarpophalangeal
(MP) joint
24. First dorsal metacarpal artery flap
• Dorsal defects
• Anatomical snuffbox: princeps pollices artery (radially) & FDMA
(unarly)
• From index-finger dorsum
• Must include subcutaneous fat and interossious muscle fascia with
the pedicle
• Thick fatty tissue with venea comitantes of artery (venous outflow)
• Flap tranpositioned via tunnering or direct incision
• Dornal site grafting
25.
26. Differentiated three different vascular patterns
for the terminal fascial branches of the FDMA
• Type I was the most frequent (11 out of 18 specimens), with three
vessels, ulnar, intermediate, and radial originating from a common
trunk that arose from the radial artery.
• Type II was far less frequent (3 out of 18 specimens) it involved two
vessels originating from a common trunk, and one separate vessel
issuing from the radial artery.
• Type III (4 out of 18 specimens), three arteries originated directly
from the radial artery
27. Treatment of thumb soft-tissue defects using a bipedicle island flap of the index finger: anatomical basis and clinical application
Hong-lue Tan • De-yan Tan • Jin-kun Zhao DOI 10.1007/s00402-013-1704-y
• The size of the soft-tissue defects ranged from
2.2 cm x 1.6 cm to 3.5 cm x 2.2 cm (mean, 3.07
cm x 2.0 cm).
• The size of the flaps ranged from 2.5 cm x 1.8
cm to 3.7 cm x 2.5 cm (mean, 3.3 cm 9 2.2 cm).
• The mean length of the dorsal and palmar
pedicle were 7.1 cm (6.8–7.4 cm) and 5.0 cm
(4.8–5.2 cm)
28. Sensitive branches
• The terminal sensitive branches of the radial nerve
are present at the dorsum of the index finger, at the
area of the proximal phalanx, lying just beneath the
skin.
• In their dissections they always found a dorsal
branch of the digital nerve, which was deeper than
the radial nerve branches, lying just over the
extensor apparatus, and ending as three terminal
branches on the area of the middle phalanx.
• This dorsal nerve branch can be sacrificed to add
innervation to the flap if necessary.
Sensate First Dorsal Metacarpal Artery Flap for Resurfacing Extensive Pulp
Defects of the Thumb
Shun-Cheng Chang, MD, Shao-Liang Chen, MD, Tim-Mo Chen, MD, Chia-Jueng Chuang, MD, Tian-Yeu Cheng, MD,
and Hsian-Jenn Wang, MD
DOI https://doi.org/10.1055/s-0038-1675369
29. Treatment of thumb soft-tissue defects using a bipedicle island flap of the index finger: anatomical basis and clinical application
Hong-lue Tan • De-yan Tan • Jin-kun Zhao . DOI 10.1007/s00402-013-1704-y
30. Treatment of thumb soft-tissue defects using a bipedicle island flap of the index finger: anatomical basis and clinical application
Hong-lue Tan • De-yan Tan • Jin-kun Zhao DOI 10.1007/s00402-013-1704-y
35. Goin flap
Postoperatively, both flaps were divided after 4 weeks
The Split Pedicle Groin Flap: New Refinement in Groin Flap Application and
Technique for Combined Thumb and Dorsal Hand Defects
Dr. Miranda DOI: 10.1097/PRS.0b013e31823af1e5
38. Sumary
Defect Flap
Tip 1-2cm2 no bone exposure Full-thickness skin graft
Tip 1-2cm2 bone exposure V-Y flap, Moberg flap, cross finger flap,
neurovascular island flap
Tip 2-3cm2 no bone exposure Full-thickness skin graft
Tip 2-3cm2 bone exposure Cross finger flap, digital dorsal perforator flap,
first dorsal metacarpal artery flap,
neurovascular island flap
Dorsal no bone, tendon exposure Full-thickness skin grap
Dorasal bone, tendon exposure Digital dorsal perforator flap. First dorsal
metacarpal artery flap
Larger, complex defect, alvusion
injury
Goin flap