Snake bite should always be considered as a medical emergency. Snake venoms are categorised based on different types of toxic components present in it. Venomous snake bite can affect nervous system as well as normal hemostasis . The most important thing to do for a snake bite is to get emergency medical help as soon as possible. The goals of pharmacotherapy are to neutralize the toxin, to reduce morbidity, and to prevent complications. Blessy Rachal Boban | Cillamol K. J | Elena Cheruvil | Sheffin Thomas | Tony Abraham ""Snake Envenomation - Case Report"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-4 , June 2019, URL: https://www.ijtsrd.com/papers/ijtsrd24037.pdf
Paper URL: https://www.ijtsrd.com/medicine/other/24037/snake-envenomation---case-report/blessy-rachal-boban
Snake bite should always be considered as a medical emergency. Snake venoms are categorised based on different types of toxic components present in it. Venomous snake bite can affect nervous system as well as normal hemostasis . The most important thing to do for a snake bite is to get emergency medical help as soon as possible. The goals of pharmacotherapy are to neutralize the toxin, to reduce morbidity, and to prevent complications. Blessy Rachal Boban | Cillamol K. J | Elena Cheruvil | Sheffin Thomas | Tony Abraham ""Snake Envenomation - Case Report"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-4 , June 2019, URL: https://www.ijtsrd.com/papers/ijtsrd24037.pdf
Paper URL: https://www.ijtsrd.com/medicine/other/24037/snake-envenomation---case-report/blessy-rachal-boban
Title-deterioration of vitiligo and de novo onset of Halo Naevi in two patie...VR Foundation
THIVI MARUTHAPPU
Introduction:
Anti-TNF drugs are widely prescribe by dermatologists as well as other specialists. With their use comes increasing awareness of potential adverse effects. Patient 1 had a 20 year history of stable vitiligo however 3 months after starting adalimumab for ankylosing spondylitis he developed rapid deterioration in his vitilgo which started to affect his face, hands and axillae in a symmetrical distribution. Adalimumab was stopped and he improved with potent topical steroids. Case 2 developed multiple halo naevi after commencing adalimumab. These were not dysplastic and he has remained on treatment.
The potential pathophysiological mechanism for developing immune mediated dermatoses with anti-tnf treatment are discussed.
Q1. Which of the following have not been described following use of anti-TNF drugs
1. Irreversible alopecia areata
2. Erythema elevatum diutunum
3. Systemic lupus erythematosus.
Q2. Which of the following is false
1.vitilgo can be cured with with anti-TNF
2. Vitiligo can improve with anti-TNF
3.vitiligo can deteriorate with anti-TNF
- Disclaimer-
This PPT is loaded as student material "as is", from the VRF Vitiligo Master Class Barcelona November 2011; VRF does not endorse or otherwise approve it.
Vitamin D deficiency ( plasma 25(OH)D levels
<50 nmol/L)(20 ng/ml) was ubiquitous in patients with ARDS and
present in the vast majority of patients at risk of
developing ARDS following oesophagectomy.
Presented by Jane Dematte, MD at the Scleroderma Patient Education Conference hosted by the Scleroderma Foundation on Saturday, October 12, 2019 in Chicago, IL
SLE is systemic autoimmune disease affecting mainly females in their reproductive age.
It has different presentations & autoantibodies that have to be followed by specialists in Rheumatology & Immunology.
It is wise to revise our Knowlege regularly to pickup the recent updates.
Title-deterioration of vitiligo and de novo onset of Halo Naevi in two patie...VR Foundation
THIVI MARUTHAPPU
Introduction:
Anti-TNF drugs are widely prescribe by dermatologists as well as other specialists. With their use comes increasing awareness of potential adverse effects. Patient 1 had a 20 year history of stable vitiligo however 3 months after starting adalimumab for ankylosing spondylitis he developed rapid deterioration in his vitilgo which started to affect his face, hands and axillae in a symmetrical distribution. Adalimumab was stopped and he improved with potent topical steroids. Case 2 developed multiple halo naevi after commencing adalimumab. These were not dysplastic and he has remained on treatment.
The potential pathophysiological mechanism for developing immune mediated dermatoses with anti-tnf treatment are discussed.
Q1. Which of the following have not been described following use of anti-TNF drugs
1. Irreversible alopecia areata
2. Erythema elevatum diutunum
3. Systemic lupus erythematosus.
Q2. Which of the following is false
1.vitilgo can be cured with with anti-TNF
2. Vitiligo can improve with anti-TNF
3.vitiligo can deteriorate with anti-TNF
- Disclaimer-
This PPT is loaded as student material "as is", from the VRF Vitiligo Master Class Barcelona November 2011; VRF does not endorse or otherwise approve it.
Vitamin D deficiency ( plasma 25(OH)D levels
<50 nmol/L)(20 ng/ml) was ubiquitous in patients with ARDS and
present in the vast majority of patients at risk of
developing ARDS following oesophagectomy.
Presented by Jane Dematte, MD at the Scleroderma Patient Education Conference hosted by the Scleroderma Foundation on Saturday, October 12, 2019 in Chicago, IL
SLE is systemic autoimmune disease affecting mainly females in their reproductive age.
It has different presentations & autoantibodies that have to be followed by specialists in Rheumatology & Immunology.
It is wise to revise our Knowlege regularly to pickup the recent updates.
With improvement in the care available for HIV patients since the mid 1990s most HIV patients are living longer. Patients with HIV are now being afflicted with conditions associated with aging including atheroscerotic heart disease. This presentation reviews the current data on coronary artery disease in HIV patients and discusses the management and prevention of these conditions in this population.
Human Genome Project is a worldwide scientific achievement. It was a thirteen-year project initiated in 1990 and completed in 2003. Human Genome Project helped a lot in the identification of diseased genes as DNA is very significant for understanding the diseased gene and their functions. It helped in the identification of disease loci for many diseases and presented their treatment through preventive measures. It identified the gene loci for many diseases like cancer, asthma, high blood pressure, diabetes type 2, obesity, Alzheimer's disease, Down's syndrome, Turner's syndrome, depression and many types of heart diseases including cardiovascular disease and coronary artery disease. This project does not directly treat the diseases but it helps in the identification of disease gene loci and then allows the treatment of disease through its preventive measures before the appearance of symptoms or at the initial stages of the disease through many techniques like gene therapy, pharmacogenomics, and targeted drug therapy. These are the helpful techniques in the diagnoses of the human disease gene locus.
International Journal of Engineering Research and Applications (IJERA) is an open access online peer reviewed international journal that publishes research and review articles in the fields of Computer Science, Neural Networks, Electrical Engineering, Software Engineering, Information Technology, Mechanical Engineering, Chemical Engineering, Plastic Engineering, Food Technology, Textile Engineering, Nano Technology & science, Power Electronics, Electronics & Communication Engineering, Computational mathematics, Image processing, Civil Engineering, Structural Engineering, Environmental Engineering, VLSI Testing & Low Power VLSI Design etc.
To date, the Registry has epidemiology and quality-of-life data from 11,180 self-registered patients with 4,196
well-characterized samples of DNA, lymphoblast lines, and sera for future research studies.
Isolated central nervous system tuberculosis is uncommon in immunocompetent patients. It resembles a pyogenic brain abscess
clinically and radiologically and poses a problem in diagnosis and treatment. Here we described a case of recurrent frontal lobe
abscess, which was diagnosed as a tubercular abscess. There was no clinical or radiological evidence of active tuberculosis
elsewhere in the body. The diagnosis of tubercular abscess was confirmed by Mycobacterium tuberculosis by Polymerase Chain
Reaction (TB-PCR) in the abscess material aspirated via a burr hole.
study of hematological paremeter in sepsis patients and its prognostic implic...RahulGupta1687
The current study was a cross-sectional study with a sample size of 117 patients with sepsis. Various hematological parameters of all the patients were obtained on day of admission (day 1) and seventh day (day 7) using hemogram reports and the difference of their statistical mean and standard deviation was estimated.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Is a medical, neurological and sometimes neurosurgical
emergency that requires a multi-disciplinary approach
Most common types are bacterial, viral and Tuberculous
Meningitis (TBM)
If the diagnosis and treatment of TBM is delayed it can result
in permanent neurological damage in 25% of patients
Gupta BK, Bharat A, Debapriya B, Baruah H. Adenosine Deaminase Levels in CSF of Tuberculous Meningitis Patients. J Clin Med Res. 2010;2(5):220–224. doi:10.4021/jocmr429w
Agarwal AK, Bansal S, Nand V. A Hospital Based Study on Estimation of Adenosine deaminase Activity (ADA) in Cerebrospinal Fluid in Various Types of Meningitis. J Clin Diagn Res. 2014;8(2):73–76.doi:10.7860/JCDR/2014/7154.4012
3. Is an enzyme which is involved in purine metabolism in which
it is responsible for conversation of adenosine and
deoxyadenosine to inosine and deoxyinosine respectively
resulting in release of ammonia
In TBM tubercle bacilli results in cell mediated immune
response which causes release of ADA by T cells
Simple, cost-effective, less time consuming
Habib A, Amin ZA, Raza SH, Aamir S. Diagnostic accuracy of cerebrospinal fluid adenosine deaminase in detecting Tuberculous Meningitis. Pakistan journal of medical sciences. 2018 Sep;34(5):1215.
Agarwal AK, Bansal S, Nand V. A Hospital Based Study on Estimation of Adenosine deaminase Activity (ADA) in Cerebrospinal Fluid in Various Types of Meningitis. J Clin Diagn Res. 2014;8(2):73–76.doi:10.7860/JCDR/2014/7154.4012
4. Bradford KL, Moretti FA, Carbonaro-Sarracino DA, Gaspar HB, Kohn DB. Adenosine deaminase (ADA)-deficient severe combined immune deficiency (SCID): molecular pathogenesis and clinical manifestations. Journal of clinical
immunology. 2017 Oct 1;37(7):626-37.
5. Trajman A, Pai M, Dheda K, van Zyl Smit R, Zwerling AA, Joshi R, Kalantri S, Daley P, Menzies D. Novel tests for diagnosing tuberculous pleural effusion: what works and what does not?. European Respiratory Journal. 2008 May
1;31(5):1098-106.
6. Sensitivity (%) 84.21
Specificity (%) 95.45
Positive Predictive Value (%) 98.97
Negative Predictive Value (%) 53.85
Diagnostic Accuracy (%) 71.32
Clinical Efficacy of CSF ADA level (u/l).
Habib A, Amin ZA, Raza SH, Aamir S. Diagnostic accuracy of cerebrospinal fluid adenosine deaminase in detecting Tuberculous Meningitis. Pakistan journal of medical sciences. 2018 Sep;34(5):1215.
7. Diagnostic accuracy of CSF ADA in detecting TBM is high
(71.32%)
Simple, cost-effective, less time consuming
