This document provides references to 42 scientific papers related to viruses and vaccines. Many of the papers discuss research on orthopoxviruses like vaccinia virus and variola virus (which causes smallpox), as well as other viruses. The papers investigate topics like viral replication, inhibition of viruses, immune responses to vaccines, and evaluation of vaccine candidates. Many of the authors are affiliated with the Institut Pasteur.

1. 1. Simple technique for in field samples collection in the cases of skin rash illness and
subsequent PCR detection of orthopoxviruses and varicella zoster virus. Dumont C,
Irenge LM, Magazani EK, Garin D, Muyembe JJ, Bentahir M, Gala JL. PLoS One.
2014 May 19;9(5):e96930. doi: 10.1371/journal.pone.0096930. eCollection 2014.
PMID: 24841633 Free PMC Article
2. NYVAC immunization induces polyfunctional HIV-specific T-cell responses in
chronically-infected, ART-treated HIV patients. Harari A, Rozot V, Cavassini M,
Bellutti Enders F, Vigano S, Tapia G, Castro E, Burnet S, Lange J, Moog C, Garin D,
Costagliola D, Autran B, Pantaleo G, Bart PA. Eur J Immunol. 2012
Nov;42(11):3038-48. doi: 10.1002/eji.201242696. Epub 2012 Oct 1. PMID: 22930439
3. Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus
give different drug-susceptibility profiles in vaccinia virus. Duraffour S, Andrei G,
Topalis D, Krečmerová M, Crance JM, Garin D, Snoeck R. J Virol. 2012
Jul;86(13):7310-25. doi: 10.1128/JVI.00355-12. Epub 2012 Apr 24. PMID: 22532673
Free PMC Article
4. Deletion of major nonessential genomic regions in the vaccinia virus Lister strain
enhances attenuation without altering vaccine efficacy in mice. Dimier J, Ferrier-
Rembert A, Pradeau-Aubreton K, Hebben M, Spehner D, Favier AL, Gratier D, Garin
D, Crance JM, Drillien R. J Virol. 2011 May;85(10):5016-26. doi:
10.1128/JVI.02359-10. Epub 2011 Mar 2. PMID: 21367889 Free PMC Article
5. Lung surfactant DPPG phospholipid inhibits vaccinia virus infection. Perino J,
Crouzier D, Spehner D, Debouzy JC, Garin D, Crance JM, Favier AL. Antiviral Res.
2011 Jan;89(1):89-97. doi: 10.1016/j.antiviral.2010.11.009. Epub 2010 Nov 21.
6. Control of vaccinia virus skin lesions by long-term-maintained IFN-gamma+TNF-
alpha+ effector/memory CD4+ lymphocytes in humans. Puissant-Lubrano B, Bossi P,
Gay F, Crance JM, Bonduelle O, Garin D, Bricaire F, Autran B, Combadière B. J
Clin Invest. 2010 May;120(5):1636-44. doi: 10.1172/JCI38506. Epub 2010 Apr 1.
PMID: 20364089 Free PMC Article
7. [Viral biosafety, biosecurity, and bioterrorism]. Garin D. Med Trop (Mars). 2010
Feb;70(1):28-32. French. PMID: 20337111
8. Differential activation profiles of Crimean-Congo hemorrhagic fever virus- and Dugbe
virus-infected antigen-presenting cells. Peyrefitte CN, Perret M, Garcia S, Rodrigues
R, Bagnaud A, Lacote S, Crance JM, Vernet G, Garin D, Bouloy M, Paranhos-
Baccalà G. J Gen Virol. 2010 Jan;91(Pt 1):189-98. doi: 10.1099/vir.0.015701-0. Epub
2009 Oct 7. PMID: 19812268 Free Article
9. Inhibition of vaccinia virus replication by peptide aptamers. Saccucci L, Crance JM,
Colas P, Bickle M, Garin D, Iseni F. Antiviral Res. 2009 Jun;82(3):134-40. doi:
10.1016/j.antiviral.2009.02.191. Epub 2009 Feb 27. PMID: 19428604
10. Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R
and G7L genes and their synergistic combination with cidofovir. Vigne S, Duraffour
S, Andrei G, Snoeck R, Garin D, Crance JM. Antimicrob Agents Chemother. 2009
Jun;53(6):2579-88. doi: 10.1128/AAC.01626-08. Epub 2009 Mar 23. PMID:
19307376 Free PMC Article
11. Specific targeting of the F13L protein by ST-246 affects orthopoxvirus production
differently. Duraffour S, Vigne S, Vermeire K, Garcel A, Vanstreels E, Daelemans D,
Yang G, Jordan R, Hruby DE, Crance JM, Garin D, Andrei G, Snoeck R. Antivir
Ther. 2008;13(8):977-90.
12. Demographic and clinical factors associated with response to smallpox vaccine in
preimmunized volunteers. Bossi P, Gay F, Fouzai I, Combadière B, Brousse G,
Lebrun-Vignes B, Crance JM, Autran B, Garin D. PLoS One. 2008;3(12):e4087. doi:

2. 10.1371/journal.pone.0004087. Epub 2008 Dec 31. PMID: 19116649 Free PMC
Article
13. Phenotypic and genetic diversity of the traditional Lister smallpox vaccine. Garcel A,
Perino J, Crance JM, Drillien R, Garin D, Favier AL. Vaccine. 2009 Jan
29;27(5):708-17. doi: 10.1016/j.vaccine.2008.11.063. Epub 2008 Dec 6. PMID:
19059294
14. Specific inhibition of orthopoxvirus replication by a small interfering RNA targeting
the D5R gene. Vigne S, Germi R, Duraffour S, Larrat S, Andrei G, Snoeck R, Garin
D, Crance JM. Antivir Ther. 2008;13(3):357-68. PMID: 18572748
15. [Healthcare response to bioterrorism]. Touze JE, Bricaire F, Garin D. Bull Acad Natl
Med. 2007 Jun;191(6):993-1003. French. PMID: 18402160
16. Short- and long-term immunogenicity and protection induced by non-replicating
smallpox vaccine candidates in mice and comparison with the traditional 1st
generation vaccine. Ferrier-Rembert A, Drillien R, Tournier JN, Garin D, Crance JM.
Vaccine. 2008 Mar 25;26(14):1794-804. doi: 10.1016/j.vaccine.2007.12.059. Epub
2008 Feb 12. PMID: 18336966
17. Activity of the anti-orthopoxvirus compound ST-246 against vaccinia, cowpox and
camelpox viruses in cell monolayers and organotypic raft cultures. Duraffour S,
Snoeck R, de Vos R, van Den Oord JJ, Crance JM, Garin D, Hruby DE, Jordan R, De
Clercq E, Andrei G. Antivir Ther. 2007;12(8):1205-16. PMID: 18240860
18. Safety, immunogenicity and protective efficacy in mice of a new cell-cultured Lister
smallpox vaccine candidate. Ferrier-Rembert A, Drillien R, Meignier B, Garin D,
Crance JM. Vaccine. 2007 Nov 28;25(49):8290-7. Epub 2007 Oct 11. PMID:
17964011
19. Substrate specificity of homogeneous monkeypox virus uracil-DNA glycosylase.
Duraffour S, Ishchenko AA, Saparbaev M, Crance JM, Garin D. Biochemistry. 2007
Oct 23;46(42):11874-81. Epub 2007 Oct 2. PMID: 17910420
20. Activities of several classes of acyclic nucleoside phosphonates against camelpox
virus replication in different cell culture models. Duraffour S, Snoeck R, Krecmerová
M, van Den Oord J, De Vos R, Holy A, Crance JM, Garin D, De Clercq E, Andrei G.
Antimicrob Agents Chemother. 2007 Dec;51(12):4410-9. Epub 2007 Sep 24. PMID:
17893157 Free PMC Article
21. Standardization of needlestick injury and evaluation of a novel virus-inhibiting
protective glove. Krikorian R, Lozach-Perlant A, Ferrier-Rembert A, Hoerner P,
Sonntag P, Garin D, Crance JM. J Hosp Infect. 2007 Aug;66(4):339-45. Epub 2007
Aug 6. PMID: 17688971
22. Genomic sequence of a clonal isolate of the vaccinia virus Lister strain employed for
smallpox vaccination in France and its comparison to other orthopoxviruses. Garcel A,
Crance JM, Drillien R, Garin D, Favier AL. J Gen Virol. 2007 Jul;88(Pt 7):1906-16.
PMID: 17554021 Free Article
23. Intranasal cowpox virus infection of the mouse as a model for preclinical evaluation of
smallpox vaccines. Ferrier-Rembert A, Drillien R, Tournier JN, Garin D, Crance JM.
Vaccine. 2007 Jun 15;25(25):4809-17. Epub 2007 Apr 24. PMID: 17499401
24. CD4+ T cells play a pivotal role in the control of cowpox virus infection in mice.
Ferrier-Rembert A, Tournier JN, Drillien R, Garin D, Crance JM. Viral Immunol.
2007 Spring;20(1):214-20. No abstract available. PMID: 17425436
25. Real-time PCR to identify variola virus or other human pathogenic orthopox viruses.
Scaramozzino N, Ferrier-Rembert A, Favier AL, Rothlisberger C, Richard S, Crance
JM, Meyer H, Garin D. Clin Chem. 2007 Apr;53(4):606-13. Epub 2007 Mar 1.
PMID: 17332145 Free Article

3. 26. [Evaluation of residual immune response against human pox virus before and after
revaccination in healthy volunteers]. Bricaire F, Combadière B, Rouleau E, Bossi P,
Garin D, Lebrun-Vignes B, Autran B. Bull Acad Natl Med. 2006 Apr-May;190(4-
5):1035-46; discussion 1046-9. French. PMID: 17195626
27. Bioterrorism: management of major biological agents. Bossi P, Garin D, Guihot A,
Gay F, Crance JM, Debord T, Autran B, Bricaire F. Cell Mol Life Sci. 2006
Oct;63(19-20):2196-212. Review. PMID: 16964582
28. Viral suppressors of RNA interference impair RNA silencing induced by a Semliki
Forest virus replicon in tick cells. Garcia S, Billecocq A, Crance JM, Prins M, Garin
D, Bouloy M. J Gen Virol. 2006 Jul;87(Pt 7):1985-9. PMID: 16760400 Free Article
29. Deadly "paleoviruses": a bioweapon Pandora's box? Tournier JN, Garin D. Lancet
Infect Dis. 2006 May;6(5):254-5. PMID: 16631539
30. Establishment of a national network of validated and qualified laboratories for
neutralizing anti-vaccinia antibodies titration. Poirier B, Leparc-Goffart I, Crance JM,
Fleury H, Garin D, Gut JP, Tissier MH, Fuchs F. Biologicals. 2005 Dec;33(4):277-
82. Epub 2005 Sep 21. PMID: 16181788
31. Evaluation of a Crimean-Congo hemorrhagic fever virus recombinant antigen
expressed by Semliki Forest suicide virus for IgM and IgG antibody detection in
human and animal sera collected in Iran. Garcia S, Chinikar S, Coudrier D, Billecocq
A, Hooshmand B, Crance JM, Garin D, Bouloy M. J Clin Virol. 2006 Feb;35(2):154-
9. Epub 2005 Aug 8. PMID: 16087395
32. DNA probe array for the simultaneous identification of herpesviruses, enteroviruses,
and flaviviruses. Korimbocus J, Scaramozzino N, Lacroix B, Crance JM, Garin D,
Vernet G. J Clin Microbiol. 2005 Aug;43(8):3779-87. PMID: 16081910 Free PMC
Article
33. Nairovirus RNA sequences expressed by a Semliki Forest virus replicon induce RNA
interference in tick cells. Garcia S, Billecocq A, Crance JM, Munderloh U, Garin D,
Bouloy M. J Virol. 2005 Jul;79(14):8942-7. PMID: 15994788 Free PMC Article
34. Nonhuman primates are relevant models for research in hematology, immunology and
virology. Hérodin F, Thullier P, Garin D, Drouet M. Eur Cytokine Netw. 2005
Jun;16(2):104-16. Review. PMID: 15941681
35. [Risk of smallpox, vaccination, bioterrorism]. Bossi P, Garin D, Combadière B,
Rouleau E, Rigaudeau S, LebrunVignes B, Martinez V, Autran B, Bricaire F. Presse
Med. 2005 Jan 29;34(2 Pt 2):177-184. Review. French. PMID:15706726
36. [Viruses considered for a third generation anti-smallpox vaccine]. Drillien R, Spehner
D, Garin D. Med Mal Infect. 2004 Jun;34 Suppl 1:S51-4. French. PMID:15676248
37. [Use of vaccinia immune globulin in the prophylaxis and the treatment of
Orthopoxvirus infections]. Crance JM, Ferrier-Rembert A, Scaramozzino N, Favier
AL, Garin D. Med Mal Infect. 2004 Jun;34 Suppl 1:S46-7. French. PMID: 15676246
38. [Update on smallpox vaccines]. Garin D, Crance JM, Fuchs F, Autran B, Drillien R.
Med Mal Infect. 2004 Jan;34(1):20-7. Review. French. PMID:15617322
39. Standardization of a neutralizing anti-vaccinia antibodies titration method: an essential
step for titration of vaccinia immunoglobulins and smallpox vaccines evaluation.
Leparc-Goffart I, Poirier B, Garin D, Tissier MH, Fuchs F, Crance JM. J Clin Virol.
2005 Jan;32(1):47-52. PMID: 15572006
40. Rapid inactivation of vaccinia virus in suspension and dried on surfaces. Ferrier A,
Garin D, Crance JM. J Hosp Infect. 2004 May;57(1):73-9. PMID: 15142719
41. In vitro inhibition of Chikungunya and Semliki Forest viruses replication by antiviral
compounds: synergistic effect of interferon-alpha and ribavirin combination. Briolant

4. S, Garin D, Scaramozzino N, Jouan A, Crance JM. Antiviral Res. 2004
Feb;61(2):111-7. PMID: 14670584
42. Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-
DNA glycosylase. Scaramozzino N, Sanz G, Crance JM, Saparbaev M, Drillien R,
Laval J, Kavli B, Garin D. Nucleic Acids Res. 2003 Aug 15;31(16):4950-7. PMID:
12907738 Free PMC Article
43. Interferon, ribavirin, 6-azauridine and glycyrrhizin: antiviral compounds active against
pathogenic flaviviruses. Crance JM, Scaramozzino N, Jouan A, Garin D. Antiviral
Res. 2003 Mar;58(1):73-9. PMID: 12719009
44. Cellular glycosaminoglycans and low density lipoprotein receptor are involved in
hepatitis C virus adsorption. Germi R, Crance JM, Garin D, Guimet J, Lortat-Jacob
H, Ruigrok RW, Zarski JP, Drouet E. J Med Virol. 2002 Oct;68(2):206-15. PMID:
12210409
45. NS3 protease of Langat tick-borne flavivirus cleaves serine protease substrates.
Scaramozzino N, Crance JM, Drouet C, Roebuck JP, Drouet E, Jouan A, Garin D.
Biochem Biophys Res Commun. 2002 May 31;294(1):16-22. PMID: 12054734
46. [Cutaneous manifestations of bioterrorism]. Carsuzaa F, Debord T, Boye T, Cavallo
JD, Pierre C, Vidal D, Jouan A, Garin D. Ann Dermatol Venereol. 2002 Jan;129(1 Pt
1):81-4. Review. French. PMID: 11937944
47. Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever
virus. Germi R, Crance JM, Garin D, Guimet J, Lortat-Jacob H, Ruigrok RW, Zarski
JP, Drouet E. Virology. 2002 Jan 5;292(1):162-8. PMID: 11878919
48. [Receptors for hepatitis C virus: update data]. Germi R, Crance JM, Garin D, Zarski
JP, Drouet E. Gastroenterol Clin Biol. 2001 Nov;25(11):1011-5. Review. French.
PMID: 11845056 Free Article
49. Quantitative real-time PCR detection of Rift Valley fever virus and its application to
evaluation of antiviral compounds. Garcia S, Crance JM, Billecocq A, Peinnequin A,
Jouan A, Bouloy M, Garin D. J Clin Microbiol. 2001 Dec;39(12):4456-61. PMID:
11724861 Free PMC Article
50. Quantitative real-time RT-PCR to study hepatitis C virus binding onto mammalian
cells. Germi R, Crance JM, Garin D, Guimet J, Zarski JP, Drouet E. Am Clin Lab.
2001 Aug;20(7):26-8. No abstract available. PMID: 11570271
51. Garin D, Peyrefitte C, Crance JM, Le Faou A, Jouan A, Bouloy M. Microbes Infect.
2001 Jul;3(9):739-45. PMID: 11489422
52. [Hepatitis C virus culture systems]. Germi R, Crance JM, Garin D, Zarski JP, Drouet
E. Pathol Biol (Paris). 2001 Apr;49(3):255-61. Review. French. PMID: 11367561
53. Comparison of flavivirus universal primer pairs and development of a rapid, highly
sensitive heminested reverse transcription-PCR assay for detection of flaviviruses
targeted to a conserved region of the NS5 gene sequences. Scaramozzino N, Crance
JM, Jouan A, DeBriel DA, Stoll F, Garin D. J Clin Microbiol. 2001 May;39(5):1922-
7. PMID: 11326014 Free PMC Article
54. Mosquito cells bind and replicate hepatitis C virus. Germi R, Crance JM, Garin D,
Guimet J, Thelu MA, Jouan A, Zarski JP, Drouet E. J Med Virol. 2001 May;64(1):6-
12. PMID: 11285562
55. Value of enterobacterial repetitive intergenic consensus PCR for study of Pasteurella
multocida strains isolated from mouths of dogs. Loubinoux J, Lozniewski A, Lion C,
Garin D, Weber M, Le Faou AE. J Clin Microbiol. 1999 Aug;37(8):2488-92. PMID:
10405390 Free PMC Article

5. 56. [Acute autochtonus hepatitis E in Lorraine]. Böhme P, Hadjadj S, Buisson Y, Garin
D, Talarmin F. Gastroenterol Clin Biol. 1998 Feb;22(2):245-6. French. PMID:
9762200 Free Article
57. Good immunogenicity of GBM strain inactivated hepatitis A vaccine in healthy male
adults. Garin D, Vidor E, Wallon M, Fanget B, Brasseur P, Delolme H, Caron F,
Mojon M, Gravey A, Humbert G, et al. Vaccine. 1995 Feb;13(2):220-4. PMID:
7625120
58. Exposure to enteroviruses and hepatitis A virus among divers in environmental waters
in France, first biological and serological survey of a controlled cohort. Garin D,
Fuchs F, Crance JM, Rouby Y, Chapalain JC, Lamarque D, Gounot AM, Aymard M.
Epidemiol Infect. 1994 Dec;113(3):541-9. PMID: 7995363 Free PMC Article
59. Transient adult T-cell leukemia/lymphoma picture during varicella infection in an
HTLV-1 carrier. D'Incan M, Combemale P, Verrier B, Garin D, Audoly G, Brunot J,
Desgranges C, Fléchaire A. Leukemia. 1994 Apr;8(4):682-7. PMID: 8152266
60. Use of cRNA digoxigenin-labelled probes for detection of enteroviruses in humans
and in the environment. Fuchs F, Leparc I, Kopecka H, Garin D, Aymard M. J Virol
Methods. 1993 May;42(2-3):217-26. PMID: 8390472
61. Efficacy of chloroquine-proguanil chemoprophylaxis against malaria in the Central
African Republic. Garin D, Lamarque D, Ringwald P, Dupuy O, Chaulet JF,
Chapalain JC, Flechaire A. Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):304-5.
PMID: 8236400
62. [Incidence of nosocomial infections in a military hospital]. Lamarque D, Garin D,
Fléchaire AO, Martignago C, Chapalain JC, Bartoli M. Presse Med. 1992 Jun
27;21(24):1110-3. French. PMID: 1387950
63. [Malaria: chloroquine resistance]. Garin D, Chaulet JF, Robet Y, Chapalain JC,
Lamarque D, Peyron F. Med Trop (Mars). 1991 Jan-Mar;51(1):29-35. French. PMID:
2072846
64. [Focus on Schistosoma intercalatum]. Garin D, Chapalain JC, Thierry J, Perrier Gros
Claude JD, Peyron F, Courtois D. Med Trop (Mars). 1990 Oct-Dec;50(4):433-40.
Review. French. PMID: 2077322
65. [Epidemiologic aspects of malaria in Gabon]. Merlin M, Dupont A, Josse R, Delaporte
E, Cheringou H, Garin D, Abandja J, Hamono B, Hengy C, Lebras J, et al. Med Trop
(Mars). 1990 Jan-Mar;50(1):39-46. French. PMID: 2195284
66. Seroepidemiology of human retroviruses in Gabon. Winkler E, Holten I, Meyer A,
Rehle T, Garin D, Mefane C, Parry JV, Schmitz H. AIDS. 1989 Feb;3(2):106-7. No
abstract available. PMID: 2496718
67. Gendrel D, Garin D, Dutailly C, Engohan E, Gendrel C, Moussavou A, Hamono B.
Pediatr Infect Dis J. 1988 Jul;7(7):523-5. PMID:3405656